Hemorrhagic shock-activated neutrophils augment TLR4 signaling-induced TLR2 upregulation in alveolar macrophages: role in hemorrhage-primed lung inflammation

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

Toll-like receptors and innate immunity

2001 • 4,138 citations

The Danger Model: A Renewed Sense of Self

2002 • 4,107 citations

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the Lps Gene Product

1999 • 3,364 citations

Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

1999 • 1,714 citations

Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)

1999 • 1,570 citations

Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein

2004 • 1,533 citations

Inferences, questions and possibilities in Toll-like receptor signalling

2004 • 1,458 citations

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

1999 • 1,381 citations

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1998 • 1,218 citations

Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 2

2000 • 1,173 citations

Differential Expression and Regulation of Toll-Like Receptors (TLR) in Human Leukocytes: Selective Expression of TLR3 in Dendritic Cells

2000 • 1,060 citations

Cutting Edge: TLR2-Deficient and MyD88-Deficient Mice Are Highly Susceptible toStaphylococcus aureusInfection

2000 • 1,046 citations

Toll-like Receptor 2 Functions as a Pattern Recognition Receptor for Diverse Bacterial Products

1999 • 939 citations

Oxidative stress and nuclear factor-κB activation

2000 • 865 citations

Human Toll-Like Receptors Mediate Cellular Activation by Mycobacterium tuberculosis

1999 • 813 citations

Adult Respiratory Distress Syndrome: Risk with Common Predispositions

1983 • 810 citations

Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family.

1993 • 627 citations

Regulation of Toll-Like Receptors in Human Monocytes and Dendritic Cells

2001 • 604 citations

Activation of Toll-Like Receptor-2 by Glycosylphosphatidylinositol Anchors from a Protozoan Parasite

2001 • 593 citations

Evolving Concepts in the Pathogenesis of Postinjury Multiple Organ Failure

1995 • 525 citations

The formation of a structure with the features of synovial lining by subcutaneous injection of air: An in vivo tissue culture system

1981 • 479 citations

SYSTEMIC INFLAMMATORY RESPONSE SYNDROME (SIRS), MULTIPLE ORGAN DYSFUNCTION SYNDROME (MODS), MULTIPLE ORGAN FAILURE (MOF)

1998 • 455 citations

Human Toll-Like Receptor 2 Mediates Monocyte Activation byListeria monocytogenes, But Not by Group B Streptococci or Lipopolysaccharide

2000 • 292 citations

Gene Expressions of Toll-Like Receptor 2, But Not Toll-Like Receptor 4, Is Induced by LPS and Inflammatory Cytokines in Mouse Macrophages

2000 • 279 citations

TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase

2003 • 259 citations

HMGB1 contributes to the development of acute lung injury after hemorrhage

2005 • 252 citations

Postinjury neutrophil priming and activation: An early vulnerable window*

1995 • 249 citations

Differential expression of Toll-like receptor 2 in human cells

2001 • 248 citations

Cutting Edge: Cells That Carry A Null Allele for Toll-Like Receptor 2 Are Capable of Responding to Endotoxin

1999 • 236 citations

Toll-like Receptor-2 Mediates Treponema Glycolipid and Lipoteichoic Acid-induced NF-κB Translocation

2001 • 233 citations

Hemorrhagic Shock Primes for Increased Expression of Cytokine-Induced Neutrophil Chemoattractant in the Lung: Role in Pulmonary Inflammation Following Lipopolysaccharide

1998 • 196 citations

NF-κB and STAT5 Play Important Roles in the Regulation of Mouse Toll-Like Receptor 2 Gene Expression

2001 • 134 citations

Role of Neutrophil NADPH Oxidase in the Mechanism of Tumor Necrosis Factor-α-induced NF-κB Activation and Intercellular Adhesion Molecule-1 Expression in Endothelial Cells

2002 • 131 citations

Regulation of Toll-Like Receptor 4 Expression in the Lung Following Hemorrhagic Shock and Lipopolysaccharide

2002 • 112 citations

A Novel Method for Isolation of Neutrophils from Murine Blood Using Negative Immunomagnetic Separation

2001 • 85 citations

NK Cells and Polymorphonuclear Neutrophils Are Both Critical for IL-2-Induced Pulmonary Vascular Leak Syndrome

2004 • 82 citations

Priming for Enhanced Alveolar Fibrin Deposition after Hemorrhagic Shock

2000 • 68 citations

Methods in laboratory investigation. Exclusion of trypan blue from microcarriers by endothelial cells: an in vitro barrier function test.

1984 • 41 citations