Role of Neutrophil NADPH Oxidase in the Mechanism of Tumor Necrosis Factor-α-induced NF-κB Activation and Intercellular Adhesion Molecule-1 Expression in Endothelial Cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Leukocyte-endothelial adhesion molecules

1994 • 2,567 citations

Oxidative stress as a mediator of apoptosis

1994 • 2,210 citations

NADPH Oxidase: An Update

1999 • 2,134 citations

TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways

1996 • 1,976 citations

Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death

1996 • 1,962 citations

Leukocyte-endothelial adhesion molecules

1994 • 1,884 citations

Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)

1992 • 1,421 citations

MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

1997 • 1,294 citations

TNF-Dependent Recruitment of the Protein Kinase RIP to the TNF Receptor-1 Signaling Complex

1996 • 1,154 citations

Signal transduction through NF-κB

1998 • 1,103 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

1995 • 920 citations

Oxidative stress and nuclear factor-κB activation

2000 • 865 citations

Resveratrol Suppresses TNF-Induced Activation of Nuclear Transcription Factors NF-κB, Activator Protein-1, and Apoptosis: Potential Role of Reactive Oxygen Intermediates and Lipid Peroxidation

2000 • 865 citations

Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62

1992 • 825 citations

Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation

1991 • 796 citations

NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules.

1997 • 576 citations

Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades

2000 • 571 citations

Transcriptional Regulation of the Intercellular Adhesion Molecule-1 Gene by Inflammatory Cytokines in Human Endothelial Cells

1995 • 540 citations

Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin

1993 • 490 citations

The p47phox mouse knock-out model of chronic granulomatous disease.

1995 • 487 citations

NADPH oxidase–derived free radicals are key oxidants in alcohol-induced liver disease

2000 • 476 citations

NF-κB as a Frequent Target for Immunosuppressive and Anti-Inflammatory Molecules**This article was accepted for publication on 27 September 1996.

1997 • 472 citations

Oxidation-Reduction and the Molecular Mechanism of a Regulatory RNA-Protein Interaction

1989 • 387 citations

A one-hour minipreparation technique for extraction of DNA-binding proteins from animal tissues.

1994 • 341 citations

Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1, and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobulin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase.

1993 • 275 citations

Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1.

1994 • 217 citations

Cytokine-induced Activation of Nuclear Factor-κB Is Inhibited by Hydrogen Peroxide through Oxidative Inactivation of IκB Kinase

2001 • 189 citations

Surfactant Protein D Regulates NF-κB and Matrix Metalloproteinase Production in Alveolar Macrophages via Oxidant-Sensitive Pathways

2001 • 162 citations

Effects of TNF- α on Expression of ICAM-1 in Human Airway Epithelial CellsIn Vitro

2000 • 145 citations

Pycnogenol inhibits tumor necrosis factor- ? -induced nuclear factor kappa B activation and adhesion molecule expression in human vascular endothelial cells

2000 • 93 citations

Mechanisms of stimulation of the respiratory burst by TNF in nonadherent neutrophils: its independence of lipidic transmembrane signaling and dependence on protein tyrosine phosphorylation and cytoskeleton.

1996 • 74 citations

Protein kinase C-activated oxidant generation in endothelial cells signals intercellular adhesion molecule-1 gene transcription.

1999 • 72 citations

NADPH oxidase subunits and superoxide production in porcine pulmonary artery endothelial cells

2000 • 58 citations

Thioredoxin Inhibits Tumor Necrosis Factor- or Interleukin-1-Induced NF-κB Activation at a Level Upstream of NF-κB-Inducing Kinase

2000 • 50 citations

Flanking Sequences for the Human Intercellular Adhesion Molecule-1 NF-κB Response Element Are Necessary for Tumor Necrosis Factor α-Induced Gene Expression

1997 • 40 citations

Refilling the inositol 1,4,5-trisphosphate-sensitive Ca2+ store in neuroblastoma x glioma hybrid NG108-15 cells

1993 • 40 citations

Tumor necrosis factor-alpha and FMLP receptors are functionally linked during FMLP-stimulated activation of adherent human neutrophils

1996 • 29 citations

The separation of the granulocytes from different rat strains A comparative study

1994 • 24 citations

Activation of NADPH-Oxidase and Its Associated Whole-cell H+ Current in Human Neutrophils by Recombinant Human Tumor Necrosis Factor α and Formyl-Methionyl-Leucyl-Phenylalanine

1995 • 15 citations