Four Pharmacologically Distinct Subtypes of α4β2 Nicotinic Acetylcholine Receptor Expressed inXenopus laevisOocytes

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat

1989 • 1,049 citations

Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons

1995 • 1,017 citations

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

1992 • 858 citations

Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors

1991 • 552 citations

Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

1991 • 463 citations

Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors h alpha 2 beta 2, h alpha 2 beta 4, h alpha 3 beta 2, h alpha 3 beta 4, h alpha 4 beta 2, h alpha 4 beta 4 and h alpha 7 expressed in Xenopus oocytes.

1997 • 387 citations

Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure

1991 • 313 citations

Differential Dependence on GluR2 Expression of Three Characteristic Features of AMPA Receptors

1997 • 298 citations

Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor

1989 • 279 citations

The actions of tubocurarine at the frog neuromuscular junction.

1979 • 265 citations

Mutation Causing Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Alters Ca²⁺Permeability, Conductance, and Gating of Human α4β2 Nicotinic Acetylcholine Receptors

1997 • 235 citations

Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine.

1996 • 223 citations

Activation of ion channels in the frog end‐plate by high concentrations of acetylcholine.

1988 • 214 citations

Structural and pharmacological characterization of the major brain nicotinic acetylcholine receptor subtype stably expressed in mouse fibroblasts.

1991 • 196 citations

Single-channel currents of rat neuronal nicotinic acetylcholine receptors expressed in xenopus oocytes

1989 • 192 citations

Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of residues that determine curare selectivity.

1993 • 186 citations

Open-Channel Blockers at the Human α4β2 Neuronal Nicotinic Acetylcholine Receptor

1998 • 181 citations

Activation and blocking of neuronal nicotinic acetylcholine receptor reconstituted in Xenopus oocytes.

1990 • 157 citations

Potentiation and Inhibition of Neuronal Nicotinic Receptors by Atropine: Competitive and Noncompetitive Effects

1997 • 157 citations

Identification of a New Component of the Agonist Binding Site of the Nicotinic α7 Homooligomeric Receptor

1995 • 147 citations

The role of the beta 4‐subunit in determining the kinetic properties of rat neuronal nicotinic acetylcholine alpha 3‐receptors.

1991 • 99 citations

Nicotinic receptor: an allosteric protein specialized for intercellular communication

1995 • 93 citations

Electrophysiology of Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes following Nuclear Injection of Genes or cDNAs

1991 • 91 citations

Pharmacological and kinetic properties of alpha 4 beta 2 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes.

1992 • 48 citations

Functional acetylcholine receptors expressed in Xenopus oocytes after injection of Torpedo beta, gamma, and delta subunit RNAs are a consequence of endogenous oocyte gene expression.

1990 • 39 citations

Properties of neuronal type acetylcholine receptors in voltage clamped mouse neuroblastoma cells

1989 • 32 citations

The beta subunit of neuronal nicotinic acetylcholine receptors is a determinant of the affinity for substance P inhibition.

1994 • 30 citations

Differential modulation of alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors expressed in Xenopus oocytes by flufenamic acid and niflumic acid

1995 • 22 citations

Differential co-expression of nicotinic acetylcholine receptor α4 and β2 subunit genes in various regions of rat brain

1996 • 13 citations