Changes in collagen metabolism in response to endothelin-1: Evidence for fibroblast heterogeneity

Methods in Enzymology , Vol

1966 • 26,261 citations

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

MODEL SYSTEMS FOR THE STUDY OF SEVEN-TRANSMEMBRANE-SEGMENT RECEPTORS

1991 • 1,357 citations

Endothelin stimulates c‐fos and c‐myc expression and proliferation of vascular smooth muscle cells

1988 • 737 citations

A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts

1989 • 485 citations

Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts.

1987 • 467 citations

The effect of transforming growth factor-beta on cell proliferation and collagen formation by lung fibroblasts.

1987 • 399 citations

Endothelin action on vascular smooth muscle involves inositol trisphosphate and calcium mobilization

1989 • 346 citations

Regulation of Bone Formation

1983 • 339 citations

Growth factor activity of endothelin on vascular smooth muscle

1990 • 325 citations

Distinct tissue distribution and cellular localization of two messenger ribonucleic acids encoding different subtypes of rat endothelin receptors.

1992 • 273 citations

Effects of endothelins on signal transduction and proliferation in human melanocytes.

1991 • 269 citations

Structure/function relationship of proteins belonging to the family of receptors coupled to GTP‐binding proteins

1991 • 241 citations

[1] Collagen: An overview

1982 • 241 citations

Endothelin, an endothelial‐dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action

1991 • 228 citations

Degradation of newly synthesized collagen.

1978 • 217 citations

Regulation of Bone Formation

1983 • 211 citations

Fibroblasts degrade newly synthesised collagen within the cell before secretion

1978 • 201 citations

Effect of cyclic AMP on the intracellular degradation of newly synthesized collagen.

1980 • 178 citations

Distinct subdomains of human endothelin receptors determine their selectivity to endothelinA-selective antagonist and endothelinB-selective agonists.

1993 • 168 citations

The selective endothelin ETA receptor antagonist BQ123 antagonizes endothelin-1-mediated mitogenesis

1992 • 146 citations

Stimulation of normal human fibroblast collagen production and processing by transforming growth factor-β

1986 • 145 citations

Endothelin-1 and Endothelin-3 Induce Chemotaxis and Replication of Pulmonary Artery Fibroblasts

1992 • 145 citations

Distinct tissue distribution and cellular localization of two messenger ribonucleic acids encoding different subtypes of rat endothelin receptors

1992 • 110 citations

Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ET-1

1992 • 100 citations

Endothelin induces potent microvascular constriction

1988 • 98 citations

Pharmacologic Characterization of an EndothelinA (ETA) Receptor Antagonist in Conscious Rats

1992 • 80 citations

Endothelin-1

1989 • 79 citations

The effect of transforming growth factor β on rates of procollagen synthesis and degradation in vitro

1991 • 77 citations

Endothelin-1 actions on resorption, collagen and noncollagen protein synthesis, and phosphatidylinositol turnover in bone organ cultures.

1992 • 75 citations

Characterization of endothelin 1 receptor and signal transduction mechanisms in rat medullary interstitial cells

1991 • 68 citations

Stimulation of the hydrolysis of phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine by endothelin, a complete mitogen for Rat-1 fibroblasts

1990 • 68 citations

Structure and function of G protein coupled receptors

1991 • 64 citations

Application of high-pressure liquid chromatography to studies of collagen production by isolated cells in culture

1990 • 58 citations

The role of vascular endothelium in the pathogenesis of connective tissue disease: endothelial injury, activation, participation and response.

1990 • 46 citations

Effects of prostaglandin E1 on collagen production and degradation in human fetal lung fibroblasts

1988 • 38 citations

Endothelin Peptides: Biological Activities, Cellular Signalling and Clinical Significance

1992 • 38 citations

Analysis of cardiovascular and pulmonary responses to endothelin-1 and endothelin-3 in the anesthetized cat.

1990 • 37 citations

Endothelin-1 actions on resorption, collagen and noncollagen protein synthesis, and phosphatidylinositol turnover in bone organ cultures

1992 • 33 citations

Actions of endothelin-1 on prostaglandin production by gestational tissues

1990 • 32 citations

Cadmium selectively inhibits fibroblast procollagen production and proliferation

1994 • 26 citations

Altered rates of collagen synthesis in in vitro aged human lung fibroblasts

1983 • 20 citations

Endothelin-1-induced prostaglandin E2 production: modulation of contractile response to endothelin-1 in porcine coronary artery

1992 • 19 citations

Endothelin-1 Is a Potent Long-Lasting Vasoconstrictor in Dog Peripheral Vasculature in vivo

1989 • 19 citations

Anomalous tritium loss in the measurement of tissue hydroxy-[5-3H]proline specific activity following chloramine-T oxidation

1982 • 13 citations

The effects of endothelin-1 on human dermal fibroblast growth and synthetic activity

1992 • 13 citations

Endothelin-1 binding sites and inositol-monophosphate formation in kidney medulla from adult and juvenile SHR and WKY rats

1991 • 5 citations