Cellular Action of Calcium Channel Blocking Drugs

Cerebral Arterial Spasm – A Controlled Trial of Nimodipine in Patients with Subarachnoid Hemorrhage

1983 • 1,148 citations

Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels

1983 • 1,010 citations

Calcium Channel Blocking Agents in the Treatment of Cardiovascular Disorders. Part II: Hemodynamic Effects and Clinical Applications

1980 • 551 citations

Calcium channels: direct identification with radioligand binding studies

1982 • 302 citations

Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.

1983 • 292 citations

[3H]nitrendipine-labeled calcium channels discriminate inorganic calcium agonists and antagonists.

1982 • 265 citations

Calcium depletion in frog muscle tubules: the decline of calcium current under maintained depolarization.

1981 • 256 citations

Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane?

1982 • 254 citations

Is Variant Angina the Coronary Manifestation of a Generalized Vasospastic Disorder?

1981 • 247 citations

Controlled Double-Blind Trial of Nifedipine in the Treatment of Raynaud's Phenomenon

1983 • 245 citations

The binding of [3H]nitrendipine to receptors for calcium channel antagonists in the heart, cerebral cortex, and ileum of rats

1982 • 227 citations

Sites of action of Ca2+ channel inhibitors

1983 • 224 citations

Clinical and manometric effects of nifedipine in patients with esophageal achalasia

1981 • 217 citations

A unitary mechanism of calcium antagonist drug action.

1983 • 214 citations

Calcium antagonists receptor sites labeled with [3H]nitrendipine

1982 • 193 citations

Interaction of calcium antagonists with cyclic AMP phosphodiesterases and calmodulin

1982 • 163 citations

Specific binding of [3H]nitrendipine to membranes from coronary arteries and heart in relation to pharmacological effects. Paradoxical stimulation by diltiazem

1982 • 158 citations

Dihydropyridine receptor in rat brain labeled with [3H]nimodipine.

1983 • 153 citations

Selective inhibition of Na+-induced Ca2+ release from heart mitochondria by diltiazem and certain other Ca2+ antagonist drugs.

1982 • 150 citations

The mechanism of inhibitory action of diltiazem on vascular smooth muscle contractility.

1981 • 149 citations

Slow inward calcium currents have no obvious role in muscle excitation–contraction coupling

1982 • 147 citations

Recent developments in vascular smooth muscle pharmacology: the post-synaptic α2-adrenoceptor

1982 • 137 citations

Evidence for multiple receptor sites within the putative calcium channel

1982 • 134 citations

Calcium antagonist and the peripheral circulation: differences and similarities between PY 108–068, nicardipine, verapamil and diltiazem

1983 • 133 citations

[3H]-Nitrendipine, a potent calcium antagonist, binds with high affinity to cardiac membranes.

1981 • 129 citations

Reflex chronotropic and inotropic effects of calcium channel-blocking agents in conscious dogs. Diltiazem, verapamil, and nifedipine compared.

1983 • 128 citations

Calcium antagonists High-affinity binding and inhibition of calcium transport in a clonal cell line.

1982 • 125 citations

Solubilization of the calcium antagonist receptor from rat brain.

1983 • 115 citations

Nisoldipine: a new, more selective calcium current blocker in cardiac Purkinje fibers.

1982 • 115 citations

Effects of Nifedipine on the Smooth Muscle of the Human Urinary Tract in Vitro and in Vivo

1978 • 112 citations

Calcium channel block and recovery from block in mammalian ventricular muscle treated with organic channel inhibitors

1982 • 112 citations

Purification of the putative calcium channel from skeletal muscle with the aid of [3H]-nimodipine binding

1983 • 98 citations

Diltiazem enhancement of [3H]nitrendipine binding to calcium channel associated drug receptor sites in rat brain synaptosomes

1982 • 97 citations

Primary pulmonary hypertension: Beneficial therapy with diltiazem

1981 • 89 citations

Calcium, Calcium Translocation, and Specific Calcium Antagonists

1978 • 81 citations

Direct inhibitory effects of some ‘calcium‐antagonists’ and trifluoperazine on the contractile proteins in smooth muscle

1983 • 78 citations

Determination of the molecular size of the nitrendipine-sensitive Ca2+ channel by radiation inactivation

1983 • 69 citations

Calcium, the Control of Smooth Muscle Function and Bronchial Hyperreactivity

1983 • 69 citations

Effects of Ca Channel Blockers on Ca Transport and Ca ATPase in Skeletal and Cardiac Sarcoplasmic Reticulum Vesicles

1982 • 65 citations

Regulation of contraction by myosin phosphorylation

1980 • 61 citations

Binding of the calcium channel blocker nitrendipine to its receptor in purified sarcolemma from canine cardiac ventricle

1983 • 57 citations

Calcium Antagonists Clinical Use in the Treatment of Angina

1983 • 54 citations

The action of D600 on frog skeletal muscle: Facilitation of excitation-contraction coupling

1977 • 48 citations

Biochemical Basis for Contraction of Vascular Smooth Muscle

1980 • 46 citations

Haemodynamic effects of nifedipine and propranolol in patients with hypertrophic obstructive cardiomyopathy.

1982 • 44 citations

Calcium‐channel gating in frog skeletal muscle membrane: effect of temperature.

1983 • 41 citations

[3H]Nimodipine specific binding to cardiac myocytes and subcellular fractions

1983 • 36 citations

The heterogeneity of the slow channel blockers (calcium antagonists)

1983 • 26 citations

Protein phosphorylation in cardiac and vascular smooth muscle

1981 • 25 citations

Effect of diltiazem on calcium transport and development of tension in heart muscle.

1982 • 22 citations

Differences Between the Effects of Calcium Antagonists in the Pithed Rat Preparation

1982 • 22 citations

Pharmacological Inhibition of Uterine Activity

1982 • 20 citations

The Regulation of Cardiac-Muscle Contraction by Troponin

1982 • 7 citations