Calcium Antagonists Clinical Use in the Treatment of Angina

Physiologic basis for assessing critical coronary stenosis

1974 • 1,503 citations

Angina pectoris I. A variant form of angina pectoris

1959 • 1,476 citations

“Variant” angina: One aspect of a continuous spectrum of vasospastic myocardial ischemia

1978 • 935 citations

Control of myocardial oxygen consumption

1971 • 799 citations

Regional Myocardial Function during Acute Coronary Artery Occlusion and Its Modification by Pharmacologic Agents in the Dog

1974 • 711 citations

Studies on the relation of the clinical manifestations of angina pectoris, coronary thrombosis, and myocardial infarction to the pathologic findings

1940 • 568 citations

Circadian variation of exercise capacity in patients with Prinzmetal's variant angina: role of exercise-induced coronary arterial spasm.

1979 • 506 citations

Characteristic electrocardiographic pattern indicating a critical stenosis high in left anterior descending coronary artery in patients admitted because of impending myocardial infarction

1982 • 496 citations

Thallium-201 myocardial perfusion imaging at rest and during exercise. Comparative sensitivity to electrocardiography in coronary artery disease.

1977 • 471 citations

The mechanisms of nitroglycerin action: stenosis vasodilatation as a major component of the drug response.

1981 • 467 citations

Role of Autonomic Nervous System in the Pathogenesis of Prinzmetal's Variant Form of Angina

1974 • 461 citations

Nifedipine Therapy for Coronary-Artery Spasm

1980 • 421 citations

Preinfarctional (Unstable) Angina—A Prospective Study— Ten Year Follow-Up

1973 • 395 citations

Calcium Channel Blocking Agents in the Treatment of Cardiovascular Disorders. Part I: Basic and Clinical Electrophysiologic Effects

1980 • 332 citations

Coronary arterial spasm and Prinzmetal's variant form of angina induced by hyperventilation and Tris-buffer infusion.

1978 • 304 citations

Exacerbation of vasotonic angina pectoris by propranolol.

1982 • 304 citations

Transient transmural reduction of myocardial blood flow demonstrated by thallium-201 scintigraphy, as a cause of variant angina.

1976 • 283 citations

Nifedipine in Unstable Angina

1982 • 237 citations

The influence of verapamil on serum digoxin concentration.

1982 • 207 citations

Failure of Intracoronary Nitroglycerin to Alleviate Pacing-Induced Angina

1972 • 202 citations

Management of unstable angina at rest by verapamil. A double-blind cross-over study in coronary care unit.

1979 • 201 citations

Treatment of variant angina with drugs: a survey of 11 cardiology institutes in Japan.

1981 • 190 citations

Double-blind Evaluation of Verapamil, Propranolol, and Isosorbide Dinitrate against a Placebo in the Treatment of Angina Pectoris

1973 • 188 citations

Dynamic coronary tone in precipitation, exacerbation and relief of angina pectoris

1981 • 187 citations

Circulating platelet products in unstable angina pectoris.

1981 • 183 citations

Long-term prognosis of “variant” angina with medical treatment

1980 • 173 citations

Nifedipine therapy for stable angina pectoris: Preliminary results of effects on angina frequency and treadmill exercise response

1979 • 173 citations

Coronary artery thrombosis in patients with unstable angina.

1981 • 168 citations

A Controlled Trial of Verapamil for Prinzmetal's Variant Angina

1981 • 166 citations

Clinical Syndrome of Variant Angina with Normal Coronary Arteriogram

1976 • 163 citations

Clinical Evaluation of Verapamil in Angina Pectoris

1968 • 152 citations

Nifedipine and propranolol: A beneficial drug interaction

1981 • 149 citations

Efficacy of diltiazem for control of symptoms of coronary arterial spasm

1980 • 143 citations

Nifedipine in the treatment of unstable angina, coronary spasm and myocardial ischemia

1981 • 142 citations

Effect of diltiazem in patients with variant angina: A randomized double-blind trial

1981 • 133 citations

Interim report of multicenter double-blind, placebo-controlled studies of nifedipine in chronic stable angina

1981 • 132 citations

Combined therapy with verapamil and propranolol in chronic stable angina

1982 • 132 citations

Ergonovine testing to detect spontaneous remissions of variant angina during long-term treatment with calcium antagonist drugs

1981 • 120 citations

Unstable angina: Natural history and determinants of prognosis

1981 • 120 citations

Safety and efficacy of diltiazem hydrochloride for the treatment of stable angina pectoris: Report of a cooperative clinical trial

1982 • 113 citations

Provocative testing with ergonovine to assess the efficacy of treatment with nifedipine, diltiazem and verapamil in variant angina

1981 • 111 citations

Pathophysiology and Treatment of Coronary Arterial Spasm

1980 • 107 citations

The hyperventilation test as a method for developing successful therapy in Prinzmetal's angina

1982 • 107 citations

Randomized double-blind comparison of nifedipine and isosorbide dinitrate in patients with coronary arterial spasm

1982 • 106 citations

Antianginal efficiency of nifedipine with and without a beta‐blocker, studied with exercise test. A double‐blind, randomized subacute study

1979 • 104 citations

Exercise testing in patients with variant angina: results, correlation with clinical and angiographic features and prognostic significance.

1982 • 103 citations

Treatment of angina at rest with nifedipine: A short-term controlled study

1980 • 101 citations

Improved exercise performance in persons with stable angina pectoris receiving diltiazem

1981 • 100 citations

Hemodynamics and Coronary Flow Following Diltiazem Administration in Anesthetized Dogs and in Humans

1980 • 100 citations

[BAY a 1040--a highly potent Ca ++ -antagonistic inhibitor of electro-mechanical coupling processes in mammalian myocardium].

1972 • 100 citations

Variant angina associated with angiographically demonstrated coronary artery spasm and REM sleep

1973 • 96 citations

Ergonovine testing in a coronary care unit

1980 • 93 citations

Verapamil versus placebo in relieving stable angina pectoris.

1982 • 86 citations

Long-term antianginal action of verapamil assessed with quantitated serial treadmill stress testing

1981 • 69 citations

Increased exercise tolerance and reduced electrocardiographic ischemia with diltiazem in patients with stable angina pectoris.

1982 • 68 citations

Clinical characteristics of patients with variant angina complicated by myocardial infarction or death within 1 month

1982 • 64 citations

Superiority of verapamil to propranolol in stable angina pectoris: a double-blind, randomized crossover trail.

1982 • 64 citations

Clinical, electrocardiographic, and haemodynamic effects of long-term use of propranolol in Prinzmetal's variant angina pectoris.

1971 • 61 citations

Prinzmetal's variant angina--response to verapamil.

1978 • 60 citations

Verapamil in stable effort angina: Effects on left ventricular function evaluated with exercise radionuclide ventriculography

1982 • 59 citations

DOUBLE BLIND EVALUATION OF ORALLY ADMINISTERED IPROVERATRIL IN PATIENTS WITH ANGINA PECTORIS

1966 • 59 citations

Significance of exercise-induced ST-segment elevation in patients without myocardial infarction.

1981 • 59 citations

Increased exercise tolerance after oral diltiazem, a calcium antagonist, in angina pectoris

1981 • 58 citations

Long-term efficacy of diltiazem in chronic stable angina associated with atherosclerosis: Effect on treadmill exercise

1982 • 55 citations

Correlation of the location of coronary arterial spasm with the lead distribution of ST segment elevation during variant angina

1980 • 50 citations

Treatment of prinzmetal's variant angina

1981 • 47 citations

Combined acebutolol/nifedipine therapy in patients with chronic coronary artery disease: Additional improvement of ischemia-induced left ventricular dysfunction

1982 • 47 citations

Comparison of verapamil and nifedipine in the treatment of variant angina pectoris: Preliminary observations in 10 patients

1981 • 45 citations

Comparison of metoprolol and verapamil in the treatment of angina pectoris

1982 • 40 citations

Comparative effects of nifedipine, verapamil, isosorbide dinitrate and propranolol on exercise-induced angina pectoris.

1979 • 39 citations

Hemodynamic effects of calcium ion antagonists after acute myocardial infarction.

1980 • 37 citations

Coronary artery spasm during exercise: treatment with verapamil.

1981 • 36 citations

Treatment of Prinzmetal's angina due to coronary artery spasm using verapamil: a report of three cases.

1978 • 32 citations

Comparison of hemodynamic effects between .BETA.-blocking agents and a new antianginal agent, diltiazem hydrochloride.

1979 • 31 citations

Hemodynamic Effects of a Single Oral Dose of Nifedipine following Acute Myocardial Infarction

1980 • 30 citations

Nifedipine blockade of ergonovine-lnduced coronary arterial spasm: Angiographic documentations

1981 • 24 citations

Verapamil therapy in variant angina pectoris refractory to nitrates

1981 • 19 citations

Influence of Different Doses of Adalat on Angina Pectoris Induced by Exercise

1975 • 14 citations

Effect of Intravenous Verapamil on Exercise Tolerance and Left Ventricular Function in Patients with Severe Exertional Angina Pectoris

1981 • 12 citations

Comparison of the antianginal efficacy of four calcium ion antagonists with propranolol

1982 • 9 citations

A prospective randomized study of propranolol versus diltiazem in patients with unstable angina

1982 • 5 citations

[Results of a field trial of the coronary drug Adalat (BAY a 1040)].

1975 • 5 citations

[Clinical application of the alkalosis induction test for coronary artery spasm].

1981 • 4 citations

Comparison of betablockers and calcium antagonists in the treatment of patients with coronary artery spasm

1982 • 3 citations

[Ergometrine test in the evaluation of drugs for spastic angina].

1981 • 1 citations