Interaction of calcium antagonists with cyclic AMP phosphodiesterases and calmodulin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The Determination of Enzyme Dissociation Constants

1934 • 11,865 citations

The determination of enzyme inhibitor constants

1953 • 4,050 citations

Specific Pharmacology of Calcium in Myocardium, Cardiac Pacemakers, and Vascular Smooth Muscle

1977 • 1,745 citations

Verapamil

1978 • 829 citations

Calcium Channel Blocking Agents in the Treatment of Cardiovascular Disorders. Part II: Hemodynamic Effects and Clinical Applications

1980 • 551 citations

Calcium-induced exposure of a hydrophobic surface on calmodulin

1980 • 520 citations

Conformational transition accompanying the binding of calcium(2+) ion to the protein activator of 3',5'-cyclic adenosine monophosphate phosphodiesterase

1977 • 472 citations

Hydrophobic regions function in calmodulin-enzyme(s) interactions.

1980 • 363 citations

New Perspectives on Calcium Antagonists

1982 • 310 citations

Purification of plant calmodulin by fluphenazine-Sepharose affinity chromatography

1979 • 252 citations

Interaction of the antihypertensive drug felodipine with calmodulin

1981 • 251 citations

Cyclic Nucleotide Phosphodiesterases: Properties, Activators, Inhibitors, Structure–Activity Relationships, and Possible Role in Drug Development

1975 • 206 citations

A ¹¹³Cd NMR study of calmodulin and its interaction with calcium, magnesium and trifluoperazine

1980 • 127 citations

Effects of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide and other calmodulin antagonists (calmodulin interacting agents) on calcium-induced contraction of rabbit aortic strips.

1981 • 116 citations

Cyclic adenosine 3':5'-monophosphate phosphodiesterase. Distinct forms in human lymphocytes and monocytes.

1976 • 90 citations

Inhibition of cyclic amp phosphodiesterase by 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)] ethyl ester 5-methyl ester hydrochloride (YC-93), a potent vasodilator

1978 • 83 citations

Purification and characterization of high-affinity cyclic adenosine monophosphate phosphodiesterase from dog kidney

1979 • 81 citations

Stimulation of enzyme activities by fragments of calmodulin

1981 • 75 citations

Selective inhibition of cyclic nucleotide phosphodiesterases by analogs of 1-methyl-3-isobutylxanthine

1977 • 74 citations

REGULATION OF MYOSIN LIGHT CHAIN KINASE BY REVERSIBLE PHOSPHORYLATION AND CALCIUM‐CALMODULIN

1980 • 60 citations

Proceedings of the British Pharmacological Society

1979 • 54 citations

Effects of nifedipine, a potent calcium-antagonistic coronary vasodilator, on atrioventricular conduction and blood flow in the isolated atrioventricular node preparation of the dog

1975 • 32 citations

Increased cyclic nucleotide phosphodiesterase activity associated with proliferation and cancer in human and murine lymphoid cells.

1977 • 32 citations

Dihydro- and tetrahydroisoquinolines as inhibitors of cyclic nucleotide phosphodiesterases from dog heart

1979 • 30 citations

Differential regulation of calcium-dependent and calcium-independent cyclic nucleotide phosphodiesterases from heart by palmitoylcarnitine and palmitoyl coenzyme A

1982 • 15 citations

Calcium Entry Blockers in Cardiologic Therapy

1981 • 10 citations