Anterior Chamber-Associated Immune Deviation

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

1981 • 1,582 citations

Regulatory T cells mediate maternal tolerance to the fetus

2004 • 1,568 citations

Natural killer cells and pregnancy

2002 • 1,216 citations

Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye.

1948 • 1,042 citations

Helminth parasites – masters of regulation

2004 • 855 citations

Ocular immune privilege: therapeutic opportunities from an experiment of nature

2003 • 744 citations

NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway

2000 • 690 citations

Professional Antigen-Presentation Function by Human γδ T Cells

2005 • 668 citations

Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice.

1998 • 536 citations

Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor.

1991 • 470 citations

The testis in immune privilege

2006 • 416 citations

CD95-Induced Apoptosis of Lymphocytes in an Immune Privileged Site Induces Immunological Tolerance

1996 • 394 citations

Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site

1999 • 360 citations

The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance

2005 • 354 citations

γδ T Cells Link Innate and Adaptive Immune Responses

2005 • 284 citations

Induction of anterior chamber-associated immune deviation requires an intact, functional spleen.

1981 • 255 citations

Transforming growth factor β—a mediator of immune deviation in seminal plasma

2002 • 253 citations

Studies on the induction of anterior chamber‐associated immune deviation (ACAID) III. Induction of ACAID depends upon intraocular transforming growth factor‐β

1992 • 250 citations

NK T Cell-Derived IL-10 Is Essential for the Differentiation of Antigen-Specific T Regulatory Cells in Systemic Tolerance

2001 • 244 citations

A novel role for TGF-beta and IL-10 in the induction of immune privilege.

1998 • 241 citations

ANTERIOR CHAMBER ASSOCIATED IMMUNE DEVIATION (ACAID): REGULATION, BIOLOGICAL RELEVANCE, AND IMPLICATIONS FOR THERAPY

2002 • 210 citations

Fluids from immune privileged sites endow macrophages with the capacity to induce antigen‐specific immune deviation via a mechanism involving transforming growth factor‐β

1992 • 206 citations

Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells

2003 • 202 citations

Antigen Markers of Macrophage Differentiation in Murine Tissues

1992 • 193 citations

Studies on the induction of anterior chamber-associated immune deviation (ACAID). 1. Evidence that an antigen-specific, ACAID-inducing, cell-associated signal exists in the peripheral blood.

1991 • 179 citations

A Novel Role for TGF-β and IL-10 in the Induction of Immune Privilege

1998 • 178 citations

MIP-2 Recruits NKT Cells to the Spleen During Tolerance Induction

2001 • 177 citations

Characterization of suppressor cells in anterior chamber-associated immune deviation (ACAID) induced by soluble antigen. Evidence of two functionally and phenotypically distinct T-suppressor cell populations.

1990 • 172 citations

Sympathetic neural modulation of the immune system

1989 • 161 citations

Impaired cell-mediated immunity in mice bearing healthy orthotopic corneal allografts.

1993 • 155 citations

The EGF-TM7 family: unusual structures at the leukocyte surface

1998 • 149 citations

Immune Privilege in the Anterior Chamber of the Eye

2002 • 145 citations

Studies on the induction of anterior chamber-associated immune deviation (ACAID). II. Eye-derived cells participate in generating blood-borne signals that induce ACAID.

1991 • 144 citations

Regulatory T cells and tolerogenic dendritic cells: from basic biology to clinical applications

2004 • 143 citations

Neuropeptide Innervation of Lymphoid Organsa

1990 • 143 citations

The Ly-49 Family: Regulation of Cytotoxicity and Cytokine Production in Murine CD3+ Cells

1998 • 137 citations

CD1d on antigen-transporting APC and splenic marginal zone B cells promotes NKT cell-dependent tolerance

2002 • 135 citations

NKT Cell-Derived RANTES Recruits APCs and CD8+ T Cells to the Spleen During the Generation of Regulatory T Cells in Tolerance

2002 • 125 citations

Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection.

1996 • 120 citations

Modulation of Macrophage Cytokine Production by ES-62, a Secreted Product of the Filarial NematodeAcanthocheilonema viteae

2001 • 116 citations

Anterior chamber-associated immune deviation promotes corneal allograft survival.

1996 • 115 citations

Cutting Edge: In Vitro-Generated Tolerogenic APC Induce CD8+ T Regulatory Cells That Can Suppress Ongoing Experimental Autoimmune Encephalomyelitis

2004 • 109 citations

γδ T Cells Are Needed for Ocular Immune Privilege and Corneal Graft Survival

2001 • 109 citations

Peptide-specific T cell clonal expansion in vivo following immunization in the eye, an immune-privileged site.

1996 • 106 citations

The eye’s view of antigen presentation

2002 • 106 citations

Immunosuppressive properties of tissues obtained from eyes with experimentally manipulated corneas.

1996 • 103 citations

Nerve‐Driven Immunity: The Direct Effects of Neurotransmitters on T‐Cell Function

2000 • 99 citations

Splenic B cells are required for tolerogenic antigen presentation in the induction of anterior chamber‐associated immune deviation (ACAID)

1998 • 93 citations

A central role for peripheral dendritic cells in the induction of acquired thymic tolerance

2003 • 85 citations

EGF-TM7: a novel subfamily of seven-transmembrane-region leukocyte cell-surface molecules

1996 • 84 citations

Role of Th1 and Th2 cells in anterior chamber‐associated immune deviation

1996 • 78 citations

Analysis of an in vitro-generated signal that induces systemic immune deviation similar to that elicited by antigen injected into the anterior chamber of the eye

1992 • 77 citations

Systemic Immune Deviation in the Brain That Does Not Depend on the Integrity of the Blood-Brain Barrier

2000 • 76 citations

Dendritic Cell Maturation Overrules H-2d–Mediated Natural Killer T (Nkt) Cell Inhibition

2001 • 76 citations

Transplantation immunology of the anterior chamber of the eye. II. Immune response to allogeneic cells.

1975 • 74 citations

Blood mononuclear cells induce regulatory NK T thymocytes in anterior chamber-associated immune deviation

2001 • 72 citations

Ocular Immune Privilege Promoted by the Presentation of Peptide on Tolerogenic B Cells in the Spleen. II. Evidence for Presentation by Qa-1

2001 • 71 citations

Evidence that peritoneal exudate cells cultured with eye-derived fluids are the proximate antigen-presenting cells in immune deviation of the ocular type.

1993 • 71 citations

Direct thymic involvement in anterior chamber-associated immune deviation: evidence for a nondeletional mechanism of centrally induced tolerance to extrathymic antigens in adult mice.

1997 • 70 citations

Alterations in cytokine production following intraocular injection of soluble protein antigen: impairment in IFN-gamma and induction of TGF-beta and IL-4 production.

1998 • 68 citations

CD25⁺, interleukin‐10‐producing CD4⁺ T cells are required for suppressor cell production and immune privilege in the anterior chamber of the eye

2003 • 67 citations

The fate of anterior chamber fluorescein in the monkey eye 1. The anterior chamber outflow pathways

1978 • 66 citations

Using Tolerance Induced Via the Anterior Chamber of the Eye to Inhibit Th2-Dependent Pulmonary Pathology

2002 • 66 citations

B cells are not essential for peripheral T-cell tolerance.

1996 • 65 citations

Regulation of Fas Ligand-Induced Apoptosis by TNF

2001 • 64 citations

Expression of Thrombospondin in TGFβ-Treated APCs and Its Relevance to Their Immune Deviation-Promoting Properties

2002 • 62 citations

Regulation of NKT Cells by Ly49: Analysis of Primary NKT Cells and Generation of NKT Cell Line

2001 • 60 citations

Intracameral inoculation of herpes simplex virus type I induces anterior chamber associated immune deviation

1982 • 60 citations

Analysis of an in vitro-generated signal that induces systemic immune deviation similar to that elicited by antigen injected into the anterior chamber of the eye.

1992 • 55 citations

Chemical sympathectomy increases the innate immune response and decreases the specific immune response in the spleen to infection with Listeria monocytogenes

2001 • 55 citations

EXPRESSION OF A NONCLASSICAL MHC CLASS Ib MOLECULE IN THE EYE1

1999 • 53 citations

Effects of experimental ocular inflammation on ocular immune privilege.

1999 • 53 citations

In vitro generation of regulatory CD8+ T cells similar to those found in mice with anterior chamber-associated immune deviation.

2000 • 52 citations

Immune privilege persists in eyes with extreme inflammation induced by intravitreal LPS

2001 • 50 citations

Alterations in Cytokine Production Following Intraocular Injection of Soluble Protein Antigen: Impairment in IFN-γ and Induction of TGF-β and IL-4 Production

1998 • 48 citations

Splenic B Cells Act as Antigen Presenting Cells for the Induction of Anterior Chamber-Associated Immune Deviation

2003 • 47 citations

Evidence for Antigen-Specific Immune Deviation in Patients With Acute Retinal Necrosis

2001 • 47 citations

Immunological profiles in patients with acute retinal necrosis

1996 • 47 citations

Intracameral injection of allogeneic lymphocytes enhances corneal graft survival.

1990 • 46 citations

γδ T cells are critical for the induction of anterior chamber‐associated immune deviation

2001 • 44 citations

Transplantation Immunology of the Anterior Chamber of the Eye

1975 • 40 citations

The induction of splenic suppressor T cells through an immune-privileged site requires an intact sympathetic nervous system

2004 • 39 citations

Differential regulation of Ly49 expression on CD4+ and CD4-CD8- (double negative) NK1.1+ T cells

2000 • 34 citations

Tolerogenic APC Generate CD8+ T Regulatory Cells That Modulate Pulmonary Interstitial Fibrosis

2004 • 33 citations

Hapten-Specific Tolerance Promoted by Calcitonin Gene-Related Peptide

2000 • 32 citations

Can nerve damage disrupt neuroendocrine immune homeostasis? Leprosy as a case in point

2002 • 29 citations

Local production of IFN-gamma abrogates the intraocular immune privilege in transgenic mice and prevents the induction of ACAID.

1994 • 27 citations

Anterior chamber inoculation of splenocytes without Fas/Fas‐ligand interaction primes for a delayed‐type hypersensitivity response rather than inducing anterior chamber‐associated immune deviation

1997 • 27 citations

The immune response and the eye. I. The effects of monoclonal antibodies to T suppressor factors in anterior chamber-associated immune deviation (ACAID).

1987 • 25 citations

Blood-borne signals that induce anterior chamber-associated immune deviation after intracameral injection of antigen.

1997 • 25 citations

The immune response and the eye: the ACAID inducing signal is dependent on the nature of the antigen.

1994 • 25 citations

Neural Influences on Induction of Contact Hypersensitivity

1999 • 25 citations

Role of Tumor Necrosis Factor Receptor Expression in Anterior Chamber-Associated Immune Deviation (ACAID) and Corneal Allograft Survival

2004 • 25 citations

Anterior chamber-associated immune deviation induced by TNP-splenocytes (TNP-ACAID). II. Suppressor T-cell networks.

1983 • 23 citations

Gamma-Delta T Cells: Immunoregulatory Functions and Immunoprotection

2001 • 20 citations

Functional analysis of cloned macrophage hybridomas. VI. Differential ability to induce immunity or suppression.

1988 • 18 citations

Impact of Inflammation on Ocular Immune Privilege

2007 • 17 citations

Mechanisms of Peripheral Tolerance following Intracameral Inoculation Are Independent of IL-13 or STAT6

2005 • 16 citations

Immune privilege in the anterior chamber of the eye: alloantigens and tumour-specific antigens presented into the anterior chamber simultaneously induce suppression and activation of delayed hypersensitivity to the respective antigens.

1992 • 14 citations

Analysis of Immune Privilege in Eyes withMycobacteria tuberculosaAdjuvant-Induced Uveitis

2005 • 10 citations

Immune deviation and ocular infections with varicella zoster virus

2004 • 9 citations

Development of F4/80 Positive Cells and CGRP Nerve Terminals in the Mouse Uvea

2003 • 3 citations

Deleted Work

1955 • 0 citations