The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance

Seven-transmembrane receptors

2002 • 2,571 citations

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

1981 • 1,582 citations

Molecular tinkering of G protein-coupled receptors: an evolutionary success

1999 • 1,479 citations

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.

1991 • 1,358 citations

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1991 • 1,074 citations

Ocular immune privilege: therapeutic opportunities from an experiment of nature

2003 • 744 citations

Freshly Isolated Peyer's Patch, but Not Spleen, Dendritic Cells Produce Interleukin 10 and Induce the Differentiation of T Helper Type 2 Cells

1999 • 656 citations

Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor.

1991 • 470 citations

Overexpression of Natural Killer T Cells Protects Vα14-Jα281 Transgenic Nonobese Diabetic Mice against Diabetes

1998 • 390 citations

Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site

1999 • 360 citations

The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF).

1996 • 343 citations

Epidermal growth factor-like modules

1993 • 343 citations

Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice.

1996 • 290 citations

Studies on the induction of anterior chamber‐associated immune deviation (ACAID) III. Induction of ACAID depends upon intraocular transforming growth factor‐β

1992 • 250 citations

The mannose receptor and other macrophage lectins

1992 • 248 citations

The role of the macrophage in immune regulation

1998 • 243 citations

Aqueous humor contains transforming growth factor-beta and a small (less than 3500 daltons) inhibitor of thymocyte proliferation.

1990 • 234 citations

Surface properties of bacillus Calmette-Guérin-activated mouse macrophages. Reduced expression of mannose-specific endocytosis, Fc receptors, and antigen F4/80 accompanies induction of Ia.

1981 • 232 citations

Molecular Cloning of F4/80, a Murine Macrophage-restricted Cell Surface Glycoprotein with Homology to the G-protein-linked Transmembrane 7 Hormone Receptor Family

1996 • 230 citations

Induction of oral tolerance to myelin basic protein in CD8-depleted mice: both CD4+ and CD8+ cells mediate active suppression.

1995 • 222 citations

ANTERIOR CHAMBER ASSOCIATED IMMUNE DEVIATION (ACAID): REGULATION, BIOLOGICAL RELEVANCE, AND IMPLICATIONS FOR THERAPY

2002 • 210 citations

The epidermal growth factor–like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans

2003 • 201 citations

Antigen Markers of Macrophage Differentiation in Murine Tissues

1992 • 193 citations

Macrophages in haemopoietic and other tissues of the developing mouse detected by the monoclonal antibody F4/80

1991 • 188 citations

Studies on the induction of anterior chamber-associated immune deviation (ACAID). 1. Evidence that an antigen-specific, ACAID-inducing, cell-associated signal exists in the peripheral blood.

1991 • 179 citations

MIP-2 Recruits NKT Cells to the Spleen During Tolerance Induction

2001 • 177 citations

Characterization of suppressor cells in anterior chamber-associated immune deviation (ACAID) induced by soluble antigen. Evidence of two functionally and phenotypically distinct T-suppressor cell populations.

1990 • 172 citations

Peptide growth factors in the intestine

2001 • 169 citations

Fc chimeric protein containing the cysteine-rich domain of the murine mannose receptor binds to macrophages from splenic marginal zone and lymph node subcapsular sinus and to germinal centers.

1996 • 156 citations

The EGF-TM7 family: unusual structures at the leukocyte surface

1998 • 149 citations

Studies on the induction of anterior chamber-associated immune deviation (ACAID). II. Eye-derived cells participate in generating blood-borne signals that induce ACAID.

1991 • 144 citations

CD4+ NKT Cells, But Not Conventional CD4+ T Cells, Are Required to Generate Efferent CD8+ T Regulatory Cells Following Antigen Inoculation in an Immune-Privileged Site

2003 • 124 citations

Characterization of the suppressor cell(s) responsible for anterior chamber-associated immune deviation (ACAID) induced in BALB/c mice by P815 cells.

1985 • 118 citations

The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation

2003 • 111 citations

Down-regulation of mannosyl receptor-mediated endocytosis and antigen F4/80 in bacillus calmette-guerin-activated mouse macrophages. Role of T lymphocytes and lymphokines

1982 • 104 citations

Human Epidermal Growth Factor (EGF) Module-containing Mucin-like Hormone Receptor 3 Is a New Member of the EGF-TM7 Family That Recognizes a Ligand on Human Macrophages and Activated Neutrophils

2001 • 98 citations

Inactivation of the F4/80 Glycoprotein in the Mouse Germ Line

2002 • 96 citations

EMR4, a Novel Epidermal Growth Factor (EGF)-TM7 Molecule Up-regulated in Activated Mouse Macrophages, Binds to a Putative Cellular Ligand on B Lymphoma Cell Line A20

2002 • 93 citations

I. Mucosal dendritic cells: their specialized role in initiating T cell responses

1999 • 92 citations

Oral tolerance in disease

1999 • 88 citations

Growth factors and the gastrointestinal tract

1998 • 88 citations

EGF-TM7: a novel subfamily of seven-transmembrane-region leukocyte cell-surface molecules

1996 • 84 citations

Control of intestinal inflammation by regulatory T cells

2001 • 84 citations

Analysis of an in vitro-generated signal that induces systemic immune deviation similar to that elicited by antigen injected into the anterior chamber of the eye

1992 • 77 citations

Blood mononuclear cells induce regulatory NK T thymocytes in anterior chamber-associated immune deviation

2001 • 72 citations

Oral Tolerance

2000 • 58 citations

Analysis of an in vitro-generated signal that induces systemic immune deviation similar to that elicited by antigen injected into the anterior chamber of the eye.

1992 • 55 citations

Role of T-lymphocytes and lymphokines

1992 • 55 citations

Class A scavenger receptors and the phagocytosis of apoptotic cells

1999 • 54 citations

Differential immunocompetence of macrophages derived using macrophage or granulocyte-macrophage colony-stimulating factor

1992 • 51 citations

Localization and Function of Tissue Macrophages

1986 • 47 citations

Identification and Characterization of a Seven Transmembrane Hormone Receptor Using Differential Display

1997 • 46 citations

A Monoclonal Antibody Directed Against the Murine Macrophage Surface Molecule F4/80 Modulates Natural Immune Response toListeria monocytogenes

1999 • 40 citations

Role of splenic B cells in the immune privilege of the anterior chamber of the eye

1995 • 38 citations

Getting to the guts of immune regulation

2002 • 32 citations

CD1-Dependent Natural Killer (NK1.1+) T Cells Are Required for Oral and Portal Venous Tolerance Induction

2002 • 24 citations

Phenotype and Function of Murine Discrete Peyer's Patch Macrophage Derived-Dendritic Cells

2003 • 9 citations

Deleted Work

1955 • 0 citations