γδ T Cells Are Needed for Ocular Immune Privilege and Corneal Graft Survival

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

Immunologically Privileged Sites

1978 • 815 citations

Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor.

1991 • 470 citations

CD95-Induced Apoptosis of Lymphocytes in an Immune Privileged Site Induces Immunological Tolerance

1996 • 394 citations

Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site

1999 • 360 citations

Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function.

1989 • 356 citations

Aerosol Insulin Induces Regulatory CD8 γδ T Cells That Prevent Murine Insulin-dependent Diabetes

1996 • 315 citations

Studies on the induction of anterior chamber‐associated immune deviation (ACAID) III. Induction of ACAID depends upon intraocular transforming growth factor‐β

1992 • 250 citations

Cutting Edge: Role of Macrophage Migration Inhibitory Factor in Inhibiting NK Cell Activity and Preserving Immune Privilege

1998 • 249 citations

A novel role for TGF-beta and IL-10 in the induction of immune privilege.

1998 • 241 citations

Aqueous humor contains transforming growth factor-beta and a small (less than 3500 daltons) inhibitor of thymocyte proliferation.

1990 • 234 citations

CD1.1 Expression by Mouse Antigen-Presenting Cells and Marginal Zone B Cells

1998 • 230 citations

Gamma delta T lymphocytes regulate the induction and maintenance of oral tolerance.

1997 • 227 citations

Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments

1993 • 216 citations

Studies on the induction of anterior chamber-associated immune deviation (ACAID). 1. Evidence that an antigen-specific, ACAID-inducing, cell-associated signal exists in the peripheral blood.

1991 • 179 citations

A Novel Role for TGF-β and IL-10 in the Induction of Immune Privilege

1998 • 178 citations

Characterization of suppressor cells in anterior chamber-associated immune deviation (ACAID) induced by soluble antigen. Evidence of two functionally and phenotypically distinct T-suppressor cell populations.

1990 • 172 citations

The distribution of HLA antigens on human corneal tissue.

1984 • 157 citations

Studies on the induction of anterior chamber-associated immune deviation (ACAID). II. Eye-derived cells participate in generating blood-borne signals that induce ACAID.

1991 • 144 citations

Depletion of IL-10- and TGF-beta-producing regulatory gamma delta T cells by administering a daunomycin-conjugated specific monoclonal antibody in early tumor lesions augments the activity of CTLs and NK cells.

1999 • 144 citations

The Expression of HLA Antigens by Cells in the Human Cornea

1984 • 124 citations

Depletion of IL-10- and TGF-β-Producing Regulatory γδ T Cells by Administering a Daunomycin-Conjugated Specific Monoclonal Antibody in Early Tumor Lesions Augments the Activity of CTLs and NK Cells

1999 • 123 citations

Characterization of gamma delta T lymphocytes at the maternal-fetal interface.

1992 • 122 citations

Anti-γδ T cell antibody blocks the induction and maintenance of oral tolerance to ovalbumin in mice

1995 • 118 citations

Crosstalk between alpha/beta T cells and gamma/delta T cells in vivo: activation of alpha/beta T-cell responses after gamma/delta T-cell modulation with the monoclonal antibody GL3.

1993 • 118 citations

Anterior chamber-associated immune deviation promotes corneal allograft survival.

1996 • 115 citations

Bacterial infection of the testis leading to autoaggressive immunity triggers apparently opposed responses of alpha beta and gamma delta T cells.

1995 • 112 citations

Detection of HLA Class I and II Antigens in Rejected Human Corneal Allografts

1985 • 107 citations

Isolation and characterization of a unique natural killer cell inhibitory factor present in the anterior chamber of the eye.

1996 • 107 citations

Splenic B cells are required for tolerogenic antigen presentation in the induction of anterior chamber‐associated immune deviation (ACAID)

1998 • 93 citations

Role of Th1 and Th2 cells in anterior chamber‐associated immune deviation

1996 • 78 citations

Analysis of an in vitro-generated signal that induces systemic immune deviation similar to that elicited by antigen injected into the anterior chamber of the eye

1992 • 77 citations

Orally induced, peptide‐specific γ/δ TCR⁺ cells suppress experimental autoimmune uveitis

1996 • 72 citations

Immunosuppressive activity of cloned natural killer (NK1.1+) T cells established from murine tumor-infiltrating lymphocytes.

1997 • 70 citations

Expression of HLA-A/B/C and -DR Locus Antigens on Epithelial, Stromal, and Endothelial Cells of the Human Cornea

1982 • 70 citations

γδ T Cells from Tolerized αβ T Cell Receptor (TCR)–deficient Mice Inhibit Contact Sensitivity-Effector T Cells In Vivo, and Their Interferon-γ Production In Vitro

1996 • 69 citations

Alterations in cytokine production following intraocular injection of soluble protein antigen: impairment in IFN-gamma and induction of TGF-beta and IL-4 production.

1998 • 68 citations

A Method for Performing Full-Thickness, Orthotopic, Penetrating Keratoplasty in the Mouse

1990 • 62 citations

Depletion of Donor-Derived Langerhans Cells Promotes Corneal Allograft Survival

1996 • 61 citations

Analysis of an in vitro-generated signal that induces systemic immune deviation similar to that elicited by antigen injected into the anterior chamber of the eye.

1992 • 55 citations

EXPRESSION OF A NONCLASSICAL MHC CLASS Ib MOLECULE IN THE EYE1

1999 • 53 citations

Role of donor-specific cytotoxic T cells in rejection of corneal allografts in normal and high-risk eyes

1996 • 51 citations

Alterations in Cytokine Production Following Intraocular Injection of Soluble Protein Antigen: Impairment in IFN-γ and Induction of TGF-β and IL-4 Production

1998 • 48 citations

Down-regulation of tumoricidal NK and NK T cell activities by MHC Kb molecules expressed on Th2-type gammadelta T and alphabeta T cells coinfiltrating in early B16 melanoma lesions.

1998 • 48 citations

Down-Regulation of Tumoricidal NK and NK T Cell Activities by MHC Kb Molecules Expressed on Th2-Type γδ T and αβ T Cells Coinfiltrating in Early B16 Melanoma Lesions

1998 • 40 citations

Induction of anterior chamber-associated immune deviation by corneal allografts placed in the anterior chamber.

1997 • 39 citations

Role of splenic B cells in the immune privilege of the anterior chamber of the eye

1995 • 38 citations

Anterior chamber-associated immune deviation induced by soluble antigens.

1989 • 35 citations

Suppressed cellular immunity in mice harboring intraocular melanomas.

1984 • 32 citations

Suppression of cytotoxic T lymphocyte activity by ?/? T cells in tumor-bearing mice

1995 • 30 citations

Local production of IFN-gamma abrogates the intraocular immune privilege in transgenic mice and prevents the induction of ACAID.

1994 • 27 citations

Blood-borne signals that induce anterior chamber-associated immune deviation after intracameral injection of antigen.

1997 • 25 citations

Correlation of anterior chamber-associated immune deviation with suppression of corneal epithelial rejection in mice.

1997 • 22 citations

The nature of antigen in the eye has a profound effect on the cytokine milieu and resultant immune response

1998 • 17 citations

Immune privilege in the anterior chamber of the eye: alloantigens and tumour-specific antigens presented into the anterior chamber simultaneously induce suppression and activation of delayed hypersensitivity to the respective antigens.

1992 • 14 citations