Regulation of Fas Ligand-Induced Apoptosis by TNF

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

The Fas Death Factor

1995 • 4,070 citations

Inhibition of death receptor signals by cellular FLIP

1997 • 2,577 citations

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

1995 • 2,436 citations

Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death

1995 • 2,114 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

BCL-2 FAMILY: Regulators of Cell Death

1998 • 1,687 citations

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1997 • 1,305 citations

Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape

1996 • 1,281 citations

Induction of apoptosis in mature T cells by tumour necrosis factor

1995 • 1,139 citations

lnterleukin-2 programs mouse αβ T lymphocytes for apoptosis

1991 • 1,027 citations

A Novel Protein That Interacts with the Death Domain of Fas/APO1 Contains a Sequence Motif Related to the Death Domain

1995 • 1,007 citations

Apoptosis signaling by death receptors

1998 • 976 citations

Immunologically Privileged Sites

1978 • 815 citations

The two different receptors for tumor necrosis factor mediate distinct cellular responses.

1991 • 815 citations

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity.

1993 • 801 citations

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity

1998 • 789 citations

Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

1995 • 706 citations

Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies.

1990 • 678 citations

Biochemical Mechanisms of IL-2–Regulated Fas-Mediated T Cell Apoptosis

1998 • 644 citations

Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor.

1993 • 573 citations

Requirement for Casper (c-FLIP) in Regulation of Death Receptor–Induced Apoptosis and Embryonic Development

2000 • 509 citations

Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis

1998 • 496 citations

Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

1997 • 433 citations

The Inhibitor of Death Receptor Signaling, Flice-Inhibitory Protein Defines a New Class of Tumor Progression Factors

1999 • 425 citations

Bcl-2 and Bax function independently to regulate cell death

1997 • 397 citations

Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.

1990 • 396 citations

CD95-Induced Apoptosis of Lymphocytes in an Immune Privileged Site Induces Immunological Tolerance

1996 • 394 citations

Regulation of the Proinflammatory Effects of Fas Ligand (CD95L)

1998 • 391 citations

Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions.

1991 • 341 citations

Immune Escape of Tumors in Vivo by Expression of Cellular Flice-Inhibitory Protein

1999 • 337 citations

CASH, a Novel Caspase Homologue with Death Effector Domains

1997 • 323 citations

Tumor necrosis factor receptor superfamily members and their ligands

1994 • 313 citations

Fas ligand is positioned in mouse uterus and placenta to prevent trafficking of activated leukocytes between the mother and the conceptus.

1997 • 291 citations

The role of FasL-induced apoptosis in immune privilege

1997 • 262 citations

Role of Fas-mediated cell death in the regulation of immune responses

1996 • 243 citations

Enhancement of antigen- and mitogen-induced human T lymphocyte proliferation by tumor necrosis factor-alpha.

1988 • 221 citations

Antiinflammatory Effects of CD95 Ligand (FasL)-induced Apoptosis

1998 • 220 citations

Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses.

1990 • 215 citations

Expression of the types A and B tumor necrosis factor (TNF) receptors is independently regulated, and both receptors mediate activation of the transcription factor NF-kappa B. TNF alpha is not needed for induction of a biological effect via TNF receptors.

1990 • 207 citations

Signaling by the TNF Receptor Superfamily and T Cell Homeostasis

2000 • 194 citations

Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site.

1997 • 183 citations

A vision of cell death: insights into immune privilege

1997 • 177 citations

Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75.

1995 • 163 citations

Cooperation of Both TNF Receptors in Inducing Apoptosis: Involvement of the TNF Receptor-Associated Factor Binding Domain of the TNF Receptor 75

1998 • 150 citations

Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1

1998 • 149 citations

TNF receptors TR60 and TR80 can mediate apoptosis via induction of distinct signal pathways.

1994 • 145 citations

Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis

2000 • 124 citations

Membrane Tumor Necrosis Factor (TNF) Induced Cooperative Signaling of TNFR60 and TNFR80 Favors Induction of Cell Death Rather Than Virus Production in HIV-infected T Cells

1997 • 76 citations

Neuropeptides modulate immune deviation induced via the anterior chamber of the eye.

1995 • 71 citations

TNF Receptor 2-Deficient CD8 T Cells Are Resistant to Fas/Fas Ligand-Induced Cell Death

2000 • 56 citations

Soluble TNF receptor production by activated T lymphocytes: differential effects of acute and chronic exposure to TNF.

1995 • 52 citations

The immune response and the eye. II. The nature of T suppressor cell induction in anterior chamber-associated immune deviation (ACAID).

1987 • 47 citations

The immune response and the eye: a role for TNF alpha in anterior chamber-associated immune deviation.

1994 • 46 citations

The immune response and the eye. III. Anterior chamber-associated immune deviation can be adoptively transferred by serum.

1989 • 41 citations