Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

1998 • 2,570 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

Calcineurin: Form and Function

2000 • 1,336 citations

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type

1998 • 998 citations

Generic Signals and Specific Outcomes

1999 • 732 citations

IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1

1999 • 651 citations

Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition

1998 • 467 citations

DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

2000 • 459 citations

MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type

2000 • 455 citations

Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway

1999 • 450 citations

A Protein Encoded within the Down Syndrome Critical Region Is Enriched in Striated Muscles and Inhibits Calcineurin Signaling

2000 • 414 citations

Independent Signals Control Expression of the Calcineurin Inhibitory Proteins MCIP1 and MCIP2 in Striated Muscles

2000 • 354 citations

Isolation and characterization of the mouse cardiac myosin heavy chain genes

1991 • 331 citations

Cardiac Hypertrophy Is Not a Required Compensatory Response to Short-Term Pressure Overload

2000 • 308 citations

A conserved family of calcineurin regulators

2000 • 300 citations

Calcineurin Signaling and Muscle Remodeling

2000 • 290 citations

Cabin 1, A Negative Regulator for Calcineurin Signaling in T Lymphocytes

1998 • 235 citations

Cain, A Novel Physiologic Protein Inhibitor of Calcineurin

1998 • 232 citations

Calcineurin Activity Is Required for the Initiation of Skeletal Muscle Differentiation

2000 • 231 citations

Expression profiling reveals distinct sets of genes altered during induction and regression of cardiac hypertrophy

2000 • 209 citations

Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo

2001 • 202 citations

Genomic Organization, Alternative Splicing, and Expression Patterns of theDSCR1(Down Syndrome Candidate Region 1) Gene

1997 • 184 citations

Cyclosporine Attenuates Pressure-Overload Hypertrophy in Mice While Enhancing Susceptibility to Decompensation and Heart Failure

1999 • 180 citations

Pressure Overload Induces Severe Hypertrophy in Mice Treated With Cyclosporine, an Inhibitor of Calcineurin

1999 • 158 citations

Calcineurin Plays a Critical Role in Pressure Overload–Induced Cardiac Hypertrophy

1999 • 147 citations

Failure of Calcineurin Inhibitors to Prevent Pressure-Overload Left Ventricular Hypertrophy in Rats

1999 • 142 citations

AKAP79 Inhibits Calcineurin through a Site Distinct from the Immunophilin-binding Region

1998 • 90 citations

A New Gene Family Including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: Characterization from Yeast to Human and Identification of DSCR1-like 2, a Novel Human Member (DSCR1L2)

2000 • 81 citations

Calcineurin Is Activated in Rat Hearts With Physiological Left Ventricular Hypertrophy Induced by Voluntary Exercise Training

2000 • 77 citations

Reversal of Cardiac Hypertrophy in Transgenic Disease Models by Calcineurin Inhibition

2000 • 76 citations

Calcineurin Blockade Prevents Cardiac Mitogen-activated Protein Kinase Activation and Hypertrophy in Renovascular Hypertension

2000 • 63 citations