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Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition

Data up to Jan 2025

Published1998
Citations467
References22
Clinical Trials (1)

Total Citations Per Year

Abstract

References (22)

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

1998 • 2,570 citations

Prevalence of Hypertrophic Cardiomyopathy in a General Population of Young Adults

1995 • 2,098 citations

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

1997 • 1,533 citations

Sensitivity of CaM Kinase II to the Frequency of Ca 2+ Oscillations

1998 • 1,263 citations

Actin Mutations in Dilated Cardiomyopathy, a Heritable Form of Heart Failure

1998 • 606 citations

Hypertrophic cardiomyopathy

1997 • 357 citations

The Mechanism of Action of FK‐506 and Cyclosporin A

1993 • 332 citations

Various hypertrophic stimuli induce distinct phenotypes in cardiomyocytes

1997 • 206 citations

Myofibril degeneration caused by tropomodulin overexpression leads to dilated cardiomyopathy in juvenile mice.

1998 • 160 citations

Molecular and Physiological Effects of Overexpressing Striated Muscle β-Tropomyosin in the Adult Murine Heart

1995 • 150 citations

Molecular analysis of the interaction of calcineurin with drug-immunophilin complexes

1994 • 116 citations

Altered Expression of Tropomodulin in Cardiomyocytes Disrupts the Sarcomeric Structure of Myofibrils

1998 • 112 citations

Contractile protein mutations and heart disease

1996 • 109 citations

Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy

1995 • 104 citations

Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice.

1997 • 100 citations

Effect of stretch on contraction and the Ca2+ transient in ferret ventricular muscles during hypoxia and acidosis

1995 • 83 citations

Mechanisms of hypertension in cardiac transplantation and the role of cyclosporine

1997 • 79 citations

Stretch‐induced increase of resting intracellular calcium concentration in single guinea‐pig ventricular myocytes

1991 • 70 citations

Molecular mechanisms regulating the myofilament response to Ca2+: Implications of mutations causal for familial hypertrophic cardiomyopathy

1997 • 47 citations

p53 Transactivation of the HIV-1 Long Terminal Repeat Is Blocked by PD 144795, a Calcineurin-Inhibitor with Anti-HIV Properties

1998 • 36 citations

Cyclosporin A and transplant coronary disease after heart transplantation: facts and fiction.

1994 • 11 citations

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