TRPC3: a versatile transducer molecule that serves integration and diversification of cellular signals

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

1999 • 1,456 citations

Molecular characterization of the drosophila trp locus: A putative integral membrane protein required for phototransduction

1989 • 1,119 citations

The trp ion channel family

2001 • 1,108 citations

Subunit composition of mammalian transient receptor potential channels in living cells

2002 • 729 citations

trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry

1996 • 688 citations

Functional interaction between InsP3 receptors and store-operated Htrp3 channels

1998 • 620 citations

Formation of Novel TRPC Channels by Complex Subunit Interactions in Embryonic Brain

2003 • 428 citations

Receptor-mediated Regulation of the Nonselective Cation Channels TRPC4 and TRPC5

2000 • 422 citations

Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension

2004 • 414 citations

Assembly of Trp1 in a Signaling Complex Associated with Caveolin-Scaffolding Lipid Raft Domains

2000 • 403 citations

Cloning and Functional Expression of a Human Ca2+-Permeable Cation Channel Activated by Calcium Store Depletion

1996 • 391 citations

On the molecular basis and regulation of cellular capacitative calcium entry: Roles for Trp proteins

1996 • 378 citations

Receptor-activated Ca2+ Influx via Human Trp3 Stably Expressed in Human Embryonic Kidney (HEK)293 Cells

1998 • 338 citations

Selective Association of TRPC Channel Subunits in Rat Brain Synaptosomes

2002 • 314 citations

Coassembly of TRP and TRPL Produces a Distinct Store-Operated Conductance

1997 • 310 citations

A novel capacitative calcium entry channel expressed in excitable cells

1998 • 308 citations

Coassembly of Trp1 and Trp3 Proteins Generates Diacylglycerol- and Ca2+-sensitive Cation Channels

2000 • 299 citations

Identification of Common Binding Sites for Calmodulin and Inositol 1,4,5-Trisphosphate Receptors on the Carboxyl Termini of Trp Channels

2001 • 296 citations

Trp1, a Candidate Protein for the Store-operated Ca2+Influx Mechanism in Salivary Gland Cells

2000 • 276 citations

The N-Terminal Domain of the IP3 Receptor Gates Store-Operated hTrp3 Channels

1999 • 268 citations

Expression of TRPC3 in Chinese Hamster Ovary Cells Results in Calcium-activated Cation Currents Not Related to Store Depletion

1997 • 259 citations

Comparison of Human TRPC3 Channels in Receptor-activated and Store-operated Modes

2002 • 231 citations

Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain

2001 • 219 citations

VAMP2-Dependent Exocytosis Regulates Plasma Membrane Insertion of TRPC3 Channels and Contributes to Agonist-Stimulated Ca2+ Influx

2004 • 197 citations

N-Linked Protein Glycosylation Is a Major Determinant for Basal TRPC3 and TRPC6 Channel Activity

2003 • 188 citations

TRP4 (CCE1) Protein Is Part of Native Calcium Release-activated Ca2+-like Channels in Adrenal Cells

2000 • 186 citations

Ca2+ Signaling by TRPC3 Involves Na+ Entry and Local Coupling to the Na+/Ca2+ Exchanger

2004 • 183 citations

TRPC1 Is Required for Functional Store-operated Ca2+ Channels

2003 • 181 citations

Human Trp3 forms both inositol trisphosphate receptor-dependent and receptor-independent store-operated cation channels in DT40 avian B lymphocytes

2001 • 179 citations

Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells

1999 • 177 citations

Trp proteins form store‐operated cation channels in human vascular endothelial cells

1998 • 162 citations

Signaling Mechanism for Receptor-activated Canonical Transient Receptor Potential 3 (TRPC3) Channels

2003 • 161 citations

A TRPC1/TRPC3-mediated Increase in Store-operated Calcium Entry Is Required for Differentiation of H19-7 Hippocampal Neuronal Cells

2004 • 156 citations

Obligatory Role of Src Kinase in the Signaling Mechanism for TRPC3 Cation Channels

2004 • 151 citations

Expression Level of the Canonical Transient Receptor Potential 3 (TRPC3) Channel Determines Its Mechanism of Activation

2003 • 150 citations

Stabilization of Cortical Actin Induces Internalization of Transient Receptor Potential 3 (Trp3)-associated Caveolar Ca2+ Signaling Complex and Loss of Ca2+ Influx without Disruption of Trp3-Inositol Trisphosphate Receptor Association

2001 • 144 citations

The Membrane Topology of Human Transient Receptor Potential 3 as Inferred from Glycosylation-scanning Mutagenesis and Epitope Immunocytochemistry

1998 • 136 citations

TRPC3 Mediates T-cell Receptor-dependent Calcium Entry in Human T-lymphocytes

2003 • 129 citations

Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion

2004 • 124 citations

Functional significance of human trp1 and trp3 in store-operated Ca²⁺entry in HEK-293 cells

2000 • 120 citations

Cloning and expression of the human transient receptor potential 4 (TRP4) gene: localization and functional expression of human TRP4 and TRP3

2000 • 120 citations

Functional expression of TrpC1: a human homologue of the Drosophila Trp channel

1998 • 109 citations

Ionic currents underlying HTRP3 mediated agonist‐dependent Ca²⁺ influx in stably transfected HEK293 cells

1998 • 106 citations

Functional characterization and physiological relevance of the TRPC3/6/7 subfamily of cation channels

2005 • 99 citations

Reduced Expression of Dentin Sialophosphoprotein Is Associated with Dysplastic Dentin in Mice Overexpressing Transforming Growth Factor-β1 in Teeth

2001 • 90 citations

Role of TRP Channels in Oxidative Stress

2004 • 67 citations

Regulation of Ca2+-release-activated Ca2+ current (Icrac) by ryanodine receptors in inositol 1,4,5-trisphosphate-receptor-deficient DT40 cells

2001 • 62 citations

Regulation of Ca2+-release-activated Ca2+ current (Icrac) by ryanodine receptors in inositol 1,4,5-trisphosphate-receptor-deficient DT40 cells

2001 • 38 citations

Expression of Trp3 Determines Sensitivity of Capacitative Ca2+ Entry to Nitric Oxide and Mitochondrial Ca2+ Handling

2001 • 30 citations

TRPC3‐like protein is involved in the capacitative cation entry induced by 1α,25‐dihydroxy‐vitamin D₃ in ROS 17/2.8 osteoblastic cells

2003 • 20 citations