Functional significance of human trp1 and trp3 in store-operated Ca²⁺entry in HEK-293 cells

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

Calcium signaling

1995 • 1,905 citations

Depletion of intracellular calcium stores activates a calcium current in mast cells

1992 • 1,748 citations

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

1999 • 1,456 citations

Store depletion and calcium influx

1997 • 1,422 citations

Molecular characterization of the drosophila trp locus: A putative integral membrane protein required for phototransduction

1989 • 1,119 citations

Inositol Trisphosphate and Calcium Signaling

1995 • 1,036 citations

PCR primer: a laboratory manual.

2003 • 743 citations

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors

1992 • 732 citations

Calcium release‐activated calcium current in rat mast cells.

1993 • 729 citations

trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry

1996 • 688 citations

TRPC1, a human homolog of a Drosophila store-operated channel.

1995 • 623 citations

Functional interaction between InsP3 receptors and store-operated Htrp3 channels

1998 • 620 citations

Regulation of calcium influx by second messengers in rat mast cells

1988 • 506 citations

Calcium signalling and cell proliferation

1995 • 501 citations

Receptor-activated Ca2+ influx: how many mechanisms for how many channels?

1994 • 403 citations

Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells.

1989 • 402 citations

Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL

1999 • 400 citations

Cloning and Functional Expression of a Human Ca2+-Permeable Cation Channel Activated by Calcium Store Depletion

1996 • 391 citations

On the molecular basis and regulation of cellular capacitative calcium entry: Roles for Trp proteins

1996 • 378 citations

Molecular cloning of a widely expressed human homologue for the Drosophila trp gene

1995 • 351 citations

Receptor-activated Ca2+ Influx via Human Trp3 Stably Expressed in Human Embryonic Kidney (HEK)293 Cells

1998 • 338 citations

Cloning and Expression of a Novel Mammalian Homolog ofDrosophila Transient Receptor Potential (Trp) Involved in Calcium Entry Secondary to Activation of Receptors Coupled by the Gq Class of G Protein

1997 • 337 citations

Coassembly of TRP and TRPL Produces a Distinct Store-Operated Conductance

1997 • 310 citations

A novel capacitative calcium entry channel expressed in excitable cells

1998 • 308 citations

Receptor-activated Ca2+ inflow in animal cells: a variety of pathways tailored to meet different intracellular Ca2+ signalling requirements

1999 • 295 citations

Molecular Cloning and Functional Characterization of a Novel Receptor-activated TRP Ca2+ Channel from Mouse Brain

1998 • 294 citations

A mammalian capacitative calcium entry channel homologous to Drosophila TRP and TRPL.

1996 • 286 citations

Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca ²⁺ entry channel

1999 • 278 citations

Expression of TRPC3 in Chinese Hamster Ovary Cells Results in Calcium-activated Cation Currents Not Related to Store Depletion

1997 • 259 citations

Molecular Cloning of a Novel Putative Ca2+Channel Protein (TRPC7) Highly Expressed in Brain

1998 • 255 citations

Activation of recombinant trp by thapsigargin in Sf9 insect cells

1994 • 226 citations

Inhibition of bradykinin- and thapsigargin-induced Ca2+ entry by tyrosine kinase inhibitors

1993 • 206 citations

Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues

1995 • 193 citations

Trp proteins form store‐operated cation channels in human vascular endothelial cells

1998 • 162 citations

Differential Expression of MammalianTRPHomologues across Tissues and Cell Lines

1997 • 153 citations

Reflections on Ca2+-channel diversity, 1988–1994

1995 • 149 citations

Store-operated calcium entry promotes shape change in pulmonary endothelial cells expressing Trp1

1998 • 135 citations

Ion Channels and Signal Transduction in Lymphocytes

1990 • 116 citations

Characterization of a Ca2+ Release-activated Nonselective Cation Current Regulating Membrane Potential and [Ca2+] Oscillations in Transgenically Derived β-Cells

1998 • 110 citations

Functional expression of TrpC1: a human homologue of the Drosophila Trp channel

1998 • 109 citations

Coexpression of Drosophila TRP and TRP-like proteins in Xenopus oocytes reconstitutes capacitative Ca ²⁺ entry

1996 • 105 citations

Depletion of Intracellular Calcium Stores Activates a Calcium Conducting Nonselective Cation Current in Mouse Pancreatic Acinar Cells

1996 • 104 citations

Chromosomal Localization and Genomic Characterization of the Mouse Melastatin Gene (Mlsn1)

1998 • 104 citations

Pharmacological and functional properties of voltagemi independent Ca2+ channels

1996 • 97 citations

Identification of four trp 1 gene variants murine pancreatic beta-cells

1997 • 91 citations

Bradykinin-induced Ca2+ entry, release, and refilling of intracellular Ca2+ stores. Relationships revealed by image analysis of individual human fibroblasts.

1992 • 87 citations

Molecular cloning and characterization of rat trp homologues from brain

1999 • 76 citations

The Role of pp60c- in the Regulation of Calcium Entry via Store-operated Calcium Channels

1997 • 66 citations

The COOH-terminal Domain of Drosophila TRP Channels Confers Thapsigargin Sensitivity

1996 • 65 citations

Intracellular Ca2+ store-operated influx of Ca2+ through TRP-R, a rat homolog of TRP, expressed in Xenopus oocytes

1998 • 48 citations

Calcium signals in growth factor signal transduction

1992 • 37 citations

Expression and Characterization of atrplHomolog from Rat

1997 • 36 citations

Cloning and expression localization of cDNA for rat homolog of TRP protein, a possible store-operated calcium (Ca2+) channel

1996 • 36 citations

Cell-to-cell variation in store-operated calcium entry in HEK-293 cells and its impact on the interpretation of data from stable clones expressing exogenous calcium channels

2000 • 15 citations

Identification and assignment of the human transient receptor potential channel 6 gene TRPC6 to chromosome 11q21→q22

1998 • 12 citations