Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells

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Calcium signaling

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Depletion of intracellular calcium stores activates a calcium current in mast cells

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Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

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Store depletion and calcium influx

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Capacitative calcium entry

1995 • 1,112 citations

trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry

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Functional interaction between InsP3 receptors and store-operated Htrp3 channels

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Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells

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Ion‐concentration dependence of the reversal potential and the single channel conductance of ion channels at the frog neuromuscular junction.

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Cloning and Functional Expression of a Human Ca2+-Permeable Cation Channel Activated by Calcium Store Depletion

1996 • 391 citations

On the molecular basis and regulation of cellular capacitative calcium entry: Roles for Trp proteins

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Rapid inactivation of depletion-activated calcium current (ICRAC) due to local calcium feedback.

1995 • 370 citations

Receptor-activated Ca2+ Influx via Human Trp3 Stably Expressed in Human Embryonic Kidney (HEK)293 Cells

1998 • 338 citations

Cloning and Expression of a Novel Mammalian Homolog ofDrosophila Transient Receptor Potential (Trp) Involved in Calcium Entry Secondary to Activation of Receptors Coupled by the Gq Class of G Protein

1997 • 337 citations

Coassembly of TRP and TRPL Produces a Distinct Store-Operated Conductance

1997 • 310 citations

A novel capacitative calcium entry channel expressed in excitable cells

1998 • 308 citations

Molecular Cloning and Functional Characterization of a Novel Receptor-activated TRP Ca2+ Channel from Mouse Brain

1998 • 294 citations

Requirement for the PDZ Domain Protein, INAD, for Localization of the TRP Store-Operated Channel to a Signaling Complex

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A mammalian capacitative calcium entry channel homologous to Drosophila TRP and TRPL.

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Agonist‐stimulated divalent cation entry into single cultured human umbilical vein endothelial cells.

1990 • 280 citations

Expression of TRPC3 in Chinese Hamster Ovary Cells Results in Calcium-activated Cation Currents Not Related to Store Depletion

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Ion Channels in Vascular Endothelium

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Activation of recombinant trp by thapsigargin in Sf9 insect cells

1994 • 226 citations

The transient receptor potential protein (Trp), a putative store-operated Ca2+ channel essential for phosphoinositide-mediated photoreception, forms a signaling complex with NorpA, InaC and InaD.

1996 • 212 citations

Activation of a Cl- current by hypotonic volume increase in human endothelial cells.

1994 • 187 citations

Endothelium as an Endocrine Organ

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Trp proteins form store‐operated cation channels in human vascular endothelial cells

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Calcium‐activated chloride channels in bovine pulmonary artery endothelial cells.

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New Light on TRP and TRPL

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Nitric oxide production in human endothelial cells stimulated by histamine requires Ca2+ influx

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TRP trapped in fly signaling web

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Membrane currents and the resting membrane potential in cultured bovine pulmonary artery endothelial cells.

1996 • 108 citations

Ionic currents underlying HTRP3 mediated agonist‐dependent Ca²⁺ influx in stably transfected HEK293 cells

1998 • 106 citations

Coexpression of Drosophila TRP and TRP-like proteins in Xenopus oocytes reconstitutes capacitative Ca ²⁺ entry

1996 • 105 citations

Thapsigargin discharges intracellular calcium stores and induces transmembrane currents in human endothelial cells

1993 • 102 citations

Store depletion triggers the calcium release-activated calcium current ( I CRAC ) in macrovascular endothelial cells: a comparison with Jurkat and embryonic kidney cell lines

1998 • 101 citations

IP3-activated Ca2+ channels in the plasma membrane of cultured vascular endothelial cells

1995 • 85 citations

Use of a bicistronic GFP-expression vector to characterise ion channels after transfection in mammalian cells

1997 • 72 citations

The COOH-terminal Domain of Drosophila TRP Channels Confers Thapsigargin Sensitivity

1996 • 65 citations

Concomitant and hormonally regulated expression of trp genes in bovine aortic endothelial cells

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Molecular characterization of a novel human PDZ domain protein with homology to INAD from Drosophila melanogaster

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Calcium entry activated by store depletion in human umbilical vein endothelial cells

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Modulation of inwardly rectifying potassium channels in cultured bovine pulmonary artery endothelial cells

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Interpreting power spectra from nonstationary membrane current fluctuations

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Nonselective Cation Channels in Endothelial Cells Derived from Human Umbilical Vein

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Delayed autoregulation of the Ca2+ signals resulting from capacitative Ca2+ entry in bovine pulmonary artery endothelial cells.

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Calcium Signalling: Cracking ICRAC in the eye

1995 • 37 citations

Expression and Characterization of atrplHomolog from Rat

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SK&F 96365 inhibits intracellular Ca2+ pumps and raises cytosolic Ca2+ concentration without production of nitric oxide and von Willebrand factor

1996 • 30 citations

Functional effects of expression of hslo Ca2+ activated K+ channels in cultured macrovascular endothelial cells

1997 • 29 citations

Kinetics of intracellular calcium release by inositol 1, 4, 5-trisphosphate and extracellular ATP in porcine cultured aortic endothelial cells

1992 • 29 citations