Motif A of bacteriophage T4 DNA polymerase: role in primer extension and DNA replication fidelity. Isolation of new antimutator and mutator DNA polymerases.

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

1992 • 1,887 citations

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

1985 • 855 citations

An attempt to unify the structure of polymerases

1990 • 640 citations

Compilation, alignment, and phylogenetic relationships of DNA polymerases

1993 • 590 citations

Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA

1993 • 473 citations

Biochemical Basis of DNA Replication Fidelity

1993 • 441 citations

Studies on the Biochemical Basis of Spontaneous Mutation

1972 • 340 citations

Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase.

1990 • 293 citations

Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4.

1990 • 261 citations

Related functional domains in virus DNA polymerases.

1987 • 243 citations

A general structure for DNA-dependent DNA polymerases

1991 • 229 citations

Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins.

1975 • 212 citations

Kinetic characterization of the polymerase and exonuclease activities of the gene 43 protein of bacteriophage T4

1992 • 207 citations

Mechanism of phosphonoacetate inhibition of herpesvirus-induced DNA polymerase

1976 • 207 citations

Spontaneous Mutation: Genetic Control of Mutation Rates in Bacteriophage T4

1969 • 206 citations

Human DNA polymerase α: predicted functional domains and relationships with viral DNA polymerases

1989 • 201 citations

Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli.

1992 • 194 citations

DNA replication fidelity.

1992 • 191 citations

Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.

1988 • 190 citations

Kinetic basis of spontaneous mutation

1982 • 187 citations

Inhibition of DNA Polymerase from Herpes Simplex Virus-Infected Wi-38 Cells by Phosphonoacetic Acid

1975 • 174 citations

Studies on the biochemical basis of spontaneous mutation

1974 • 170 citations

Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms.

1979 • 167 citations

Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates.

1992 • 145 citations

Primary structure of T4 DNA polymerase. Evolutionary relatedness to eucaryotic and other procaryotic DNA polymerases.

1988 • 134 citations

Translationsl regulation of expression of the bacteriophage T4 lysozyme gene

1986 • 122 citations

Pyrophosphate analogues as inhibitors of DNA polymerases of cytomegalovirus, herpes simplex virus and cellular origin

1982 • 93 citations

A Deoxyribonuclease Induced By Infection with Bacteriophage T2

1964 • 93 citations

Processive proofreading is intrinsic to T4 DNA polymerase.

1992 • 87 citations

Control of mutation frequency by bacteriophage T4 DNA polymerase. I. The CB120 antimutator DNA polymerase is defective in strand displacement.

1976 • 84 citations

Amino acid changes coded by bacteriophage T4 DNA polymerase mutator mutants

1988 • 84 citations

DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies.

1991 • 69 citations

Genetic and biochemical studies of bacteriophage T4 DNA polymerase 3'-->5'-exonuclease activity.

1993 • 69 citations

PROPERTIES OF BACTERIOPHAGE T4 MUTANTS DEFECTIVE IN DNA POLYMERASE

1970 • 68 citations

The purification and properties of deoxyguanosine triphosphate triphosphohydrolase from Escherichia coli.

1988 • 63 citations

A unique deoxyguanosine triphosphatase is responsible for the optA1 phenotype of Escherichia coli.

1988 • 54 citations

Reduced in vivo mutagenesis by mutant herpes simplex DNA polymerase involves improved nucleotide selection.

1985 • 52 citations

Bacteriophage T4 DNA polymerase mutations that confer sensitivity to the PPi analog phosphonoacetic acid

1993 • 49 citations

Bacteriophage T4 gene 44/62 and gene 45 polymerase accessory proteins stimulate hydrolysis of duplex DNA by T4 DNA polymerase.

1982 • 48 citations

Characterization of the stimulatory effect of T4 gene 45 protein and the gene protein complex on DNA synthesis by T4 DNA polymerase

1984 • 48 citations

Cloning and expression of T4 DNA polymerase.

1987 • 42 citations

Bacterial and phage mutations that reveal helix-unwinding activities required for bacteriophage T4 DNA replication.

1983 • 41 citations

Structure and regulation of the gene for dGTP triphosphohydrolase from Escherichia coli.

1990 • 39 citations

Locations of amino acid substitutions in bacteriophage T4 tsL56 DNA polymerase predict an N-terminal exonuclease domain

1989 • 32 citations

Can DNA polymerase I (Klenow fragment) serve as a model for other polymerases?

1991 • 26 citations

Isolation of bacteriophage T4 DNA polymerase mutator mutants

1986 • 22 citations

Structure-function studies of the bacteriophage T4 DNA polymerase

1985 • 11 citations