The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes- predisposing non-Aspbeta57 MHC class II molecules

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1994 • 1,553 citations

Binding of immunogenic peptides to Ia histocompatibility molecules

1985 • 1,209 citations

Insulin-Dependent Diabetes Mellitus

1996 • 1,171 citations

Identification of self peptides bound to purified HLA-B27

1991 • 844 citations

A one-step purification of membrane proteins using a high efficiency immunomatrix.

1982 • 782 citations

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

1995 • 583 citations

MHC Class-II Molecules and Autoimmunity

1991 • 521 citations

Isolation and characterization of antigen-la complexes involved in T cell recognition

1986 • 470 citations

Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding.

1990 • 248 citations

Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides.

1996 • 247 citations

On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs.

1991 • 242 citations

Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules

1994 • 234 citations

Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line.

1987 • 222 citations

Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to Type 1 (insulin-dependent) diabetes mellitus

1993 • 213 citations

Peptide binding characteristics of the coeliac disease-associated DQ(α1*0501, β1*0201) molecule

1996 • 150 citations

Allele-specific motifs characterize HLA-DQ interactions with a diabetes-associated peptide derived from glutamic acid decarboxylase.

1996 • 144 citations

Characterization of the specificity of peptide binding to four DR haplotypes.

1990 • 134 citations

HLA-DQB1 codon 57 is critical for peptide binding and recognition.

1996 • 110 citations

Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2)

1997 • 101 citations

Peptide binding specificity of major histocompatibility complex class I resolved into an array of apparently independent subspecificities: quantitation by peptide libraries and improved prediction of binding

1996 • 99 citations

Decrypting the structure of major histocompatibility complex class I-restricted cytotoxic T lymphocyte epitopes with complex peptide libraries.

1995 • 99 citations

Identification of a putative motif for binding of peptides to HLA-DQ2

1996 • 96 citations

The distribution of DR4 haplotypes in sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci

1995 • 96 citations

Self peptides isolated from MHC glycoproteins of non-obese diabetic mice.

1994 • 92 citations

A Peptide-binding Motif for I-Ag7, the Class II Major Histocompatibility Complex (MHC) Molecule of NOD and Biozzi AB/H Mice

1997 • 90 citations

Molecular characterization of the diabetes-associated mouse MHC class II protein, I-Ag7

1997 • 81 citations

Quantitation of peptide anchor residue contributions to class I major histocompatibility complex molecule binding.

1993 • 70 citations

Natural ligand motifs of closely related HLA-DR4 molecules predict features of rheumatoid arthritis associated peptides

1996 • 64 citations

Mhc Class-Ii Molecules And Autoimmunity

1991 • 42 citations

Peptide motifs of HLA-DR4/DR53 (DRB1*0405/DRB4*0101) molecules

1994 • 31 citations

Characterization of an HLA-DQ2-specific monoclonal antibody

1995 • 25 citations

HLA-DQ2-restricted T-cell recognition of gluten-derived peptides in celiac disease influence of amino acid substitutions in the membrane distal domain of DQβ 1∗0201

1995 • 18 citations

DQB1*0202 and the new DQB1*0203 allele: a fourth pair of DQB1 alleles differing only at codon 57

1997 • 14 citations

Representative Combinatorial Peptide Libraries: An Approach to Reduce both Synthesis and Screening Efforts

1994 • 6 citations