Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

[17] Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis

1983 • 1,115 citations

Two populations of Ia-like molecules on a human B cell line.

1980 • 1,112 citations

A one-step purification of membrane proteins using a high efficiency immunomatrix.

1982 • 782 citations

Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.

1982 • 740 citations

Deglycosylation of glycoproteins by trifluoromethanesulfonic acid

1981 • 728 citations

Role of MHC Gene Products in Immune Regulation

1981 • 705 citations

endo-beta-N-acetylglucosaminidase F: endoglycosidase from Flavobacterium meningosepticum that cleaves both high-mannose and complex glycoproteins.

1982 • 689 citations

The class II molecules of the human and murine major histocompatibility complex

1984 • 664 citations

The carbohydrate-binding specificity of pea and lentil lectins. Fucose is an important determinant.

1981 • 568 citations

The interaction of Ricinus communis agglutinin with normal and tumor cell surfaces

1972 • 514 citations

Structural determinants of concanavalin A specificity for oligosaccharides

1979 • 467 citations

Detection of a novel human class II HLA antigen

1983 • 387 citations

Immunochemistry in Practice

1983 • 355 citations

Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens

1982 • 308 citations

Isotypic and allotypic variation of human class II histocompatibility antigen α-chain genes

1984 • 261 citations

Genetic Complexity and Expression of Human Class II Histocompatibility Antigens

1985 • 247 citations

[10] Gas-liquid chromatography of carbohydrates

1972 • 244 citations

LFA-1, LFA-2, and LFA-3 antigens are involved in CTL-target conjugation.

1984 • 227 citations

Isolation and immunologic characterization of a human. B-lymphocyte-specific, cell surface antigen.

1976 • 211 citations

Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules.

1982 • 197 citations

Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains.

1984 • 190 citations

Structural determinants of Phaseolus vulgaris erythroagglutinating lectin for oligosaccharides.

1983 • 185 citations

Demonstration of structural polymorphism among HLA-DR light chains by two-dimensional gel electrophoresis.

1980 • 170 citations

Carbohydrate moiety of HLA antigens. Antigenic properties and amino acid sequences around the site of glycosylation.

1977 • 169 citations

Human Ia molecules carrying DC1 determinants differ in both α- and β-subunits from Ia molecules carrying DR determinants

1981 • 169 citations

cDNA clone for the heavy chain of the human B cell alloantigen DC1: strong sequence homology to the HLA-DR heavy chain.

1982 • 162 citations

Serologic and immunochemical characterization of the specificity of four monoclonal antibodies to distinct antigenic determinants expressed on subpopulations of human Ia-like antigens.

1981 • 152 citations

Direct evidence of homology between human DC-1 antigen and murine I-A molecules

1982 • 144 citations

Differential inhibition of HLA-D- or SB-directed secondary lymphoproliferative responses with monoclonal antibodies detecting human Ia-like determinants.

1982 • 135 citations

Monoclonal Antibodies to HLA–DRw Determinants

1980 • 132 citations

Purification and structural characterisation of human HLA-linked B-cell antigens

1977 • 129 citations

[12] Lactoperoxidase-catalyzed iodination as a tool for investigation of proteins

1980 • 124 citations

The amino acid sequence and gene organization of the heavy chain of the HLA-DR antigen: homology to immunoglobulins.

1982 • 121 citations

Purification of immunologically functional subsets of human Ia-like antigens on a monoclonal antibody (Q5/13) immunoadsorbent.

1980 • 120 citations

A human Ia cytoplasmic determinant located on multiple forms of invariant chain (gamma, gamma 2, gamma 3).

1984 • 119 citations

Structure and polymorphism of the HLA class II SB light chain genes.

1984 • 115 citations

Alpha and beta chains of SB and DR antigens are structurally distinct

1982 • 112 citations

Biosynthesis and maturation of HLA-DR antigens in vivo.

1981 • 111 citations

DNA sequence and characterization of human class II major histocompatibility complex beta chains from the DR1 haplotype.

1985 • 109 citations

Genetic variation in glycosylation of the fourth component of murine complement. Association with hemolytic activity.

1982 • 108 citations

Distinct forms of both alpha and beta subunits are present in the human Ia molecular pool.

1981 • 92 citations

Further characterization of HLA-DS molecules: implications for studies assessing the role of human Ia molecules in cell interactions and disease susceptibility.

1983 • 90 citations

Isolation of I–A subregion-like molecules from subhuman primates and man

1981 • 81 citations

Analysis of the oligosaccharides on the HLA-DR and DC1 B cell antigens.

1983 • 70 citations

Both chains of HLA-DR bind to the membrane with a penultimate hydrophobic region and the heavy chain is phosphorylated at its hydrophilic carboxyl terminus.

1979 • 69 citations

Monoclonal antibody identifies a new Ia-like (p29,34) polymorphic system linked to the HLA-D/DR region

1981 • 69 citations

Immunochemically purified DR antigens in liposomes stimulate xenogeneic cytolytic T cells in secondary in vitro cultures

1986 • 50 citations

Biochemical characterization of Ia antigens. I. Characterization of the 31K polypeptide associated with I-A subregion Ia antigens.

1980 • 46 citations

The human invariant chain is the core protein of the human class II-associated proteoglycan.

1986 • 42 citations

Distribution of antigenic determinants recognized by three monoclonal antibodies (Q2/70, Q5/6 and Q5/13) on human Ia-like alloantigens and on their subunits

1981 • 41 citations

Demonstration at the single‐cell level of the existence of distinct clusters of epitopes in two predefined human Ia molecular subsets

1982 • 41 citations

Submit and disulfide structure of monomeric and dimeric forms of detergent-soluble HLA antigens.

1977 • 39 citations

A novel HLA-D/DR-like antigen specific for human B lymphoid cells. Biochemical evidence for similarity to but nonidentity with known HLA-D/DR antigens.

1983 • 38 citations

Monoclonal mouse anti‐I‐A^k and anti‐I‐E^k antibodies cross‐reacting with HLA‐DR supertypic and subtypic determinants rather than classical DR allelic specificities

1982 • 34 citations

Isolation of heavy chain class switch variants of a monoclonal anti-DC1 hybridoma cell line: Effective conversion of noncytotoxic IgG1 antibodies to cytotoxic IgG2 antibodies

1983 • 34 citations

Cell surface expression of invariant gamma-chain of class II histocompatibility antigens in human skin.

1986 • 30 citations

Analysis of the structural heterogeneity and polymorphism of human Ia antigens. Four distinct subsets of molecules are coexpressed in the Ia pool of both DR1,1 homozygous and DR3,W6 heterozygous B cell lines.

1984 • 27 citations

A homozygous human cell line contains three subsets of HLA-DR-like antigens distinguishable by amino acid sequencing

1982 • 26 citations

A monoclonal antibody that recognizes the α chain of HLA-DR antigens

1986 • 21 citations

Serological, functional, and immunochemical characterization of a monoclonal antibody (MoAb Q2/70) to human Ia-like antigens

1980 • 17 citations

NH2-terminal sequence of the ? and ? chains of human DC-1 antigen isolated from the JY cell line. Homology with murine I-A molecules

1983 • 16 citations

[54] Use of the HLA-DR antigens incorporated into liposomes to generate HLA-DR specific cytotoxic T lymphocytes

1984 • 15 citations

[53] Use of monoclonal antibody immunoaffinity columns to purify subsets of human HLA-DR antigens

1984 • 4 citations