Inhibition of the NT-3 Receptor TrkC, Early in Chick Embryogenesis, Results in Severe Reductions in Multiple Neuronal Subpopulations in the Dorsal Root Ganglia

Antibodies, a laboratory manual

1989 • 12,929 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Functional Interactions of Neurotrophins and Neurotrophin Receptors

1995 • 825 citations

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

1994 • 804 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

A BDNF autocrine loop in adult sensory neurons prevents cell death

1995 • 743 citations

Severe sensory and sympathetic deficits in mice lacking neurotrophin-3

1994 • 635 citations

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

1994 • 620 citations

Neurotrophins promote motor neuron survival and are present in embryonic limb bud

1993 • 619 citations

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

1993 • 525 citations

Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons

1992 • 521 citations

The role of neurotrophins in the developing nervous system

1994 • 472 citations

Neuronal death in the spinal ganglia of the chick embryo and its reduction by nerve growth factor

1981 • 407 citations

Alternative forms of rat TrkC with different functional capabilities

1993 • 374 citations

Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons

1993 • 338 citations

The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells

1993 • 290 citations

Sympathetic neuroblasts undergo a developmental switch in trophic dependence

1993 • 279 citations

Proliferative and degenerative events in the early development of chick dorsal root ganglia. I. Normal development

1978 • 252 citations

Sensory Neurons; Diversity, Development and Plasticity

1994 • 226 citations

Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons.

1994 • 225 citations

Signal Transduction Mediated by the Truncated trkB Receptor Isoforms, trkB.T1 and trkB.T2

1997 • 224 citations

TrkA cross-linking mimics neuronal responses to nerve growth factor.

1994 • 222 citations

NT-3 stimulates sympathetic neuroblast proliferation by promoting precursor survival

1993 • 218 citations

The early migration of neural crest cells in the trunk region of the avian embryo: An electron microscopic study

1978 • 216 citations

Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival

1992 • 195 citations

Neurotrophin 3 is a mitogen for cultured neural crest cells.

1992 • 192 citations

Neurotrophin 3 supports the survival of developing muscle sensory neurons in culture.

1993 • 190 citations

trkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificities.

1993 • 178 citations

Non-TrkA-expressing small DRG neurons are lost in TrkA deficient mice

1995 • 165 citations

Neurotrophin-3 induces neural crest-derived cells from fetal rat gut to develop in vitro as neurons or glia

1994 • 118 citations

A spatial and temporal analysis of dorsal root and sympathetic ganglion formation in the avian embryo

1988 • 113 citations

Sensory ganglia require neurotrophin-3 early in development

1994 • 107 citations

Dorsal root ganglion cell death and surviving cell numbers in relation to the development of sensory innervation in the rat hindlimb

1994 • 105 citations

P0 is an early marker of the schwann cell lineage in chickens

1991 • 99 citations

Neuronal precursor cells in chick dorsal root ganglia: Differentiation and survival in vitro

1988 • 98 citations

Proliferation, Differentiation, and Survival of Rat Sensory Neuron Precursors in Vitro Require Specific Trophic Factors

1995 • 95 citations

Muscle sensory neurons require neurotrophin-3 from peripheral tissues during the period of normal cell death

1995 • 95 citations

Isoforms of the avian TrkC receptor: A novel kinase insertion dissociates transformation and process outgrowth from survival

1994 • 72 citations

Neurotrophin‐3 affects proliferation and differentiation of distinct neural crest cells and is present in the early neural tube of avian embryos

1993 • 63 citations

Expression of trkC receptor mRNA during development of the avian nervous system

1994 • 61 citations

Embryonic sensory development: Local expression of neurotrophin‐3 and target expression of nerve growth factor

1994 • 58 citations

Molecular cloning and cellular localization of trk C in the chicken embryo

1993 • 52 citations

Expression of trk and neurotrophin mRNA in dorsal root and sympathetic ganglia of the quail during development

1994 • 52 citations

Environmental influences on neural crest cell migration

1993 • 50 citations

Target specificity and size of avian sensory neurons supported in vitro by nerve growth factor, brain‐derived neurotrophic factor, and neurotrophin‐3

1994 • 15 citations