Sympathetic neuroblasts undergo a developmental switch in trophic dependence

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Appendix G: In Situ Hybridization: An Improved Whole-Mount Method for Xenopus Embryos

1991 • 2,082 citations

Mechanisms and Functions of Cell Death

1991 • 2,061 citations

Nerve growth factor.

1968 • 2,025 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Cell death and control of cell survival in the oligodendrocyte lineage

1992 • 1,331 citations

Regressive Events in Neurogenesis

1984 • 1,330 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

1990 • 1,238 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

1989 • 1,097 citations

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation.

1988 • 909 citations

The changing scene of neurotrophic factors

1991 • 827 citations

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1991 • 819 citations

Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture

1988 • 760 citations

Binding of brain-derived neurotrophic factor to the nerve growth factor receptor

1990 • 702 citations

Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

1990 • 700 citations

Destruction of the sympathetic ganglia in mammals by an antiserum to a nerve-growth protein

1960 • 651 citations

The nerve growth factor family of receptors

1992 • 649 citations

Principles of neural development

1985 • 627 citations

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1989 • 604 citations

Horizontal integration and cortical dynamics

1992 • 589 citations

Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor

1987 • 555 citations

Primary structure and biological activity of a novel human neurotrophic factor

1990 • 553 citations

The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3

1991 • 530 citations

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

1993 • 525 citations

Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons

1992 • 521 citations

Cells Expressing mRNA for Neurotrophins and their Receptors During Embryonic Rat Development

1992 • 499 citations

Essential role of the nerve growth factor in the survival and maintenance of dissociated sensory and sympathetic embryonic nerve cells in vitro

1963 • 417 citations

Neuronal death in the spinal ganglia of the chick embryo and its reduction by nerve growth factor

1981 • 407 citations

Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor

1985 • 384 citations

Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity.

1991 • 359 citations

Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development.

1990 • 342 citations

A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids

1986 • 337 citations

Vasoactive intestinal peptide regulates mitosis, differentiation and survival of cultured sympathetic neuroblasts

1990 • 317 citations

Keeping track of neurotrophin receptors

1991 • 297 citations

Trkl3 mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor

1991 • 294 citations

[53] Long-term culture of dissociated sympathetic neurons

1979 • 294 citations

Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions.

1991 • 255 citations

Basic FGF induces neuronal differentiation, cell division, and NGF dependence in chromaffin cells: A sequence of events in sympathetic development

1988 • 252 citations

Changes in neurotrophin responsiveness during the development of cerebellar granule neurons

1992 • 240 citations

The NGF-inducible SCG10 mRNA encodes a novel membrane-bound protein present in growth cones and abundant in developing neurons

1988 • 239 citations

Insulin growth factors regulate the mitotic cycle in cultured rat sympathetic neuroblasts.

1988 • 239 citations

Cellular targets and trophic functions of neurotrophin-3 in the developing rat hippocampus

1992 • 225 citations

Role of nerve growth factor in the development of rat sympathetic neurons in vitro. I. Survival, growth, and differentiation of catecholamine production.

1977 • 218 citations

A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF

1990 • 205 citations

Neurotrophic factors promote the maturation of developing sensory neurons before they become dependent on these factors for survival

1992 • 195 citations

Neurotrophin 3 is a mitogen for cultured neural crest cells.

1992 • 192 citations

Nerve growth factor is a mitogen for cultured chromaffin cells

1985 • 192 citations

Role of the neurotrophic factors BDNF and NGF in the commitment of pluripotent neural crest cells

1991 • 176 citations

Relationship between differentiation and terminal mitosis: chick sensory and ciliary neurons differentiate after terminal mitosis of precursor cells, whereas sympathetic neurons continue to divide after differentiation

1987 • 167 citations

Principles of neural development

1985 • 160 citations

Developmental changes of nerve growth factor levels in sympathetic ganglia and their target organs

1988 • 145 citations

Antibody markers identify a common progenitor to sympathetic neurons and chromaffin cells in vivo and reveal the timing of commitment to neuronal differentiation in the sympathoadrenal lineage

1991 • 137 citations

Expression of basic fibroblast growth factor in the nervous system of early avian embryos

1990 • 128 citations

Signal transduction and the fate of the R7 photoreceptor in Drosophila

1991 • 128 citations

The duration of neurotrophic factor independence in early sensory neurons is matched to the time course of target field innervation

1991 • 123 citations

Neuroblast mitosis in dissociated culture: regulation and relationship to differentiation.

1990 • 113 citations

Acidic fibroblast growth factor atimulates adrenal chromaffin cells to proliferate and to extend neurites, but is not a long term survival factor

1988 • 109 citations

Nerve growth factor-independent development of embryonic mouse sympathetic neurons in dissociated cell culture

1985 • 104 citations

The survival of early chick sympathetic neurons in vitro is dependent on a suitable substrate but independent of NGF

1989 • 103 citations

Role of nerve growth factor in the development of rat sympathetic neurons in vitro. II. Developmental studies.

1977 • 88 citations

Specific high-affinity receptors for neurotrophin-3 on sympathetic neurons

1993 • 79 citations

The Role of Growth Factors in the Control of Neurogenesis

1990 • 76 citations

Signal transduction during C. elegans vulval induction

1991 • 75 citations

Ultrastructural changes in sympathetic neurons of newborn and adult mice treated with nerve growth factor

1971 • 60 citations

ROLE OF NERVE GROWTH FACTOR IN THE DEVELOPMENT OF RAT SYMPATHETIC NEURONS IN VITRO

1977 • 57 citations

Expression of noradrenergic and cholinergic traits by sympathetic neurons cultured without serum

1985 • 54 citations

Signal transduction and the fate of the R7 photoreceptor in drosophila

1991 • 51 citations

Antibodies against mouse nerve growth factor interfere in vivo with the development of avian sensory and sympathetic neurones

1988 • 44 citations

Depolarization and insulin like growth factor-l (IGF-l) differentially regulate the mitotic cycle in cultured rat sympathetic neuroblasts

1989 • 42 citations

Signal transduction during C. elegans vulval induction

1991 • 23 citations