Participation of upstream stimulator factor (USF) in cadmium-induction of the mouse metallothionein-I gene

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Oxidative mechanisms in the toxicity of metal ions

1995 • 4,127 citations

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

1997 • 3,743 citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

The “initiator” as a transcription control element

1989 • 1,597 citations

The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

1991 • 1,564 citations

Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1

1986 • 1,473 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

The MyoD family and myogenesis: Redundancy, networks, and thresholds

1993 • 1,062 citations

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase ₁ gene

1996 • 1,027 citations

In Vivo Footprinting of a Muscle Specific Enhancer by Ligation Mediated PCR

1989 • 972 citations

[69] Overview of metallothionein

1991 • 793 citations

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium.

1994 • 624 citations

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

1990 • 584 citations

Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants.

1990 • 522 citations

The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression.

1994 • 489 citations

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

1990 • 484 citations

A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene.

1984 • 424 citations

Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.

1993 • 382 citations

Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse.

1993 • 381 citations

Biochimica et biophysica acta. Protein structure and molecular enzymology

2002 • 370 citations

Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element.

1992 • 353 citations

Regulation of metallothionein genes by heavy metalsappears to be mediated by a zinc-sensitive inhibitor that interacts with aconstitutively active transcription factor, MTF-1.

1994 • 351 citations

Interaction cloning: identification of a helix-loop-helix zipper protein that interacts with c-Fos

1992 • 348 citations

Ubiquitous expression of the 43- and 44-kDa forms of transcription factor USF in mammalian cells

1994 • 328 citations

Enhanced Sensitivity to Oxidative Stress in Cultured Embryonic Cells from Transgenic Mice Deficient in Metallothionein I and II Genes

1995 • 302 citations

Glutathione S-Transferases: Gene Structure and Regulation of Expression

1993 • 300 citations

Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements

1994 • 265 citations

Metallothionein III : biological roles and medical implications

1993 • 253 citations

Antioxidant response element

1994 • 245 citations

Oxidative Stress Activates Metal-responsive Transcription Factor-1 Binding Activity

1996 • 237 citations

Effects of different DNA polymerases in ligation-mediated PCR: enhanced genomic sequencing and in vivo footprinting.

1992 • 232 citations

Consequences of heteromeric interactions among helix-loop-helix proteins.

1993 • 226 citations

Cadmium evokes inositol polyphosphate formation and calcium mobilization

1989 • 212 citations

Immunochemical Characterization and Transacting Properties of Upstream Stimulatory Factor Isoforms

1996 • 202 citations

Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1

1994 • 197 citations

The DNA Binding Activity of Metal Response Element-binding Transcription Factor-1 Is Activated in vivo and in Vitro by Zinc, but Not by Other Transition Metals

1998 • 186 citations

Regulation of metallothionein gene expression.

1990 • 177 citations

Constitutive and metal-inducible protein:DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting.

1988 • 176 citations

The HIP1 Binding Site Is Required for Growth Regulation of the Dihydrofolate Reductase Gene Promoter

1992 • 172 citations

The major late transcription factor binds to and activates the mouse metallothionein I promoter.

1987 • 160 citations

Members of the USF family of helix-loop-helix proteins bind DNA as homo- as well as heterodimers.

1992 • 160 citations

ARE- and TRE-mediated Regulation of Gene Expression

1995 • 140 citations

Reversible Activation of Mouse Metal Response Element-Binding Transcription Factor 1 DNA Binding Involves Zinc Interaction with the Zinc Finger Domain

1997 • 127 citations

The ontogeny of expression of murine metallothionein: Comparison with the α-fetoprotein gene

1984 • 127 citations

Base preferences for DNA binding by the bHLH-Zip protein USF: effects of MgCl₂on specificity and comparison with binding of Myc family members

1994 • 126 citations

The helix-loop-helix containing transcription factor USF binds to and transactivates the promoter of the p53 tumor suppressor gene

1993 • 119 citations

Transgenic Mice That Overexpress Metallothionein-I Resist Dietary Zinc Deficiency

1996 • 115 citations

TAL1, TAL2 and LYL1: a family of basic helix-loop-helix proteins implicated in T cell acute leukaemia.

1993 • 112 citations

Transforming Growth Factor βl-Responsive Element: Closely Associated Binding Sites for USF and CCAAT-Binding Transcription Factor-Nuclear Factor I in the Type 1 Plasminogen Activator Inhibitor Gene

1992 • 112 citations

An E-box Region within the Prostaglandin Endoperoxide Synthase-2 (PGS-2) Promoter Is Required for Transcription in Rat Ovarian Granulosa Cells

1996 • 110 citations

The cellular transcription factor USF cooperates with varicella-zoster virus immediate-early protein 62 to symmetrically activate a bidirectional viral promoter.

1994 • 101 citations

Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Characterization of a DNA-protein interaction at the antioxidant responsive element and induction by 12-O-tetradecanoylphorbol 13-acetate.

1993 • 100 citations

A cDNA from a mouse pancreatic β cell encoding a putative transcription factor of the insulin gene

1990 • 91 citations

Pancreatic Islet Expression of the Homeobox Factor STF-1 Relies on an E-box Motif That Binds USF

1996 • 88 citations

Evidence that the transcription factor USF is a component of the human beta-globin locus control region heteromeric protein complex.

1993 • 88 citations

Cell-specific metallothionein gene expression in mouse decidua and placentae

1989 • 86 citations

Regulation of mammalian neural development by helix-loop-helix transcription factors.

1995 • 84 citations

Enhancement of rat and human phagocyte superoxide anion radical production by cadmium in vitro

1982 • 76 citations

The helix-loop-helix transcription factor USF (upstream stimulating factor) binds to a regulatory sequence of the human insulin gene enhancer

1993 • 69 citations

Definition of the Transcriptional Activation Domain of Recombinant 43-Kilodalton USF

1992 • 66 citations

Transforming growth factor beta 1-responsive element: closely associated binding sites for USF and CCAAT-binding transcription factor-nuclear factor I in the type 1 plasminogen activator inhibitor gene.

1992 • 64 citations

Activation of the complete mouse metallothionein gene locus in the maternal deciduum

1996 • 61 citations

Cross-family interaction between the bHLHZip USF and bZip Fra1 proteins results in down-regulation of AP1 activity

1997 • 52 citations

Identification of a Contractile-responsive Element in the Cardiac α-Myosin Heavy Chain Gene

1995 • 52 citations

A Three-protein-DNA Complex on a B Cell-specific Domain of the Immunoglobulin μ Heavy Chain Gene Enhancer

1997 • 51 citations

The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter.

1992 • 51 citations

NO is more important than PGI2 in maintaining low vascular tone in feto-placental vessels

1993 • 51 citations

The Basic Helix-Loop-Helix-Zipper Transcription Factor USF1 Regulates Expression of the Surfactant Protein-A Gene

1997 • 50 citations

Selective Utilization of Basic Helix-Loop-Helix–Leucine Zipper Proteins at the Immunoglobulin Heavy-Chain Enhancer

1997 • 50 citations

Differential requirements for p21ras and protein kinase C in the regulation of neuronal gene expression by nerve growth factor and neurokines.

1994 • 36 citations

Participation of altered upstream stimulatory factor in the induction of rat heme oxygenase-1 by cadmium

1996 • 33 citations

Autoactivation of Xenopus MyoD transcription and its inhibition by USF.

1997 • 31 citations

Stimulation of myosin light-chain kinase by Cd2+ and Pb2+

1995 • 28 citations

USF2/FIP Associates with the b-Zip Transcription Factor, c-Maf, via Its bHLH Domain and Inhibits c-Maf DNA Binding Activity

1997 • 24 citations

Definition of the transcriptional activation domain of recombinant 43-kilodalton USF.

1992 • 24 citations

In vivo effects of cadmium on calmodulin and calmodulin regulated enzymes in rat brain.

1991 • 19 citations

Role of Helix-Loop-Helix Proteins in Drosophila Neurogenesis

1990 • 18 citations