Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells

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Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.

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Inhibition of DNA Topoisomerase IIα Gene Expression by the p53 Tumor Suppressor

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Glutathione peroxidase-1 overexpression prevents ceramide production and partially inhibits apoptosis in doxorubicin-treated human breast carcinoma cells.

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Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung.

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2001 • 130 citations

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p53-dependent global genomic repair of benzo[a]pyrene-7,8-diol-9,10-epoxide adducts in human cells.

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Rapid isolation, hydrolysis and chromatography of formaldehyde-modified DNA

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Altered Regulation of Cyclin G in Human Breast Cancer and Its Specific Localization at Replication Foci in Response to DNA Damage in p53+/+ Cells

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Prolactin Suppresses Glucocorticoid-Induced Thymocyte Apoptosis in Vivo

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Formation of Benzo[a]pyrene Diol Epoxide−DNA Adducts at Specific Guanines within K-ras and p53 Gene Sequences: Stable Isotope-Labeling Mass Spectrometry Approach

2002 • 86 citations

Enzymatic aspects of the phenol (aryl) sulfotransferases^*

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Cytosine Methylation in a CpG Sequence Leads to Enhanced Reactivity with Benzo[a]pyrene Diol Epoxide That Correlates with a Conformational Change

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DNA Adducts from a Tumorigenic Metabolite of Benzo[a]pyrene Block Human RNA Polymerase II Elongation in a Sequence- and Stereochemistry-dependent Manner

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Aromatic Hydrocarbon Receptor (AhR)·AhR Nuclear Translocator- and p53-mediated Induction of the Murine Multidrug Resistance mdr1 Gene by 3-Methylcholanthrene and Benzo(a)pyrene in Hepatoma Cells

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Enhanced sensitivity to anti-benzo(a)pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells.

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DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[ a ]pyrene

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Comparison of DNA adduct formation in mice fed coal tar or benzo[a]pyrene

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Identification of genes responsive to BPDE treatment in HeLa cells using cDNA expression assays

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p55Cdc/Cdc20 Overexpression Promotes Early G ₁ /S Transition in Myeloid Cells

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Induction of mutations in TK6 human lymphoblastoid cells by ethyl methanesulphonate, benzo[ <italic>a</italic> ]pyrene and benzidine

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