Unique gene expression patterns in liver and kidney associated with exposure to chemical toxicants.

Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring

1999 • 11,586 citations

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

Mechanisms of carbon tetrachloride toxicity

1989 • 1,250 citations

REGULATION OF GENE EXPRESSION BY REACTIVE OXYGEN

1999 • 1,102 citations

AH RECEPTOR SIGNALING PATHWAYS

1996 • 898 citations

Microarrays: biotechnology's discovery platform for functional genomics

1998 • 793 citations

Microarrays and toxicology: The advent of toxicogenomics

1999 • 673 citations

DNA microarrays in drug discovery and development

1999 • 662 citations

Cadmium, Gene Regulation, and Cellular Signalling in Mammalian Cells

1997 • 530 citations

Mx protein: Constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus

1986 • 479 citations

Global response of Saccharomyces cerevisiae to an alkylating agent

1999 • 426 citations

Studies on lipid peroxidation in rat tissues following administration of low and moderate doses of cadmium chloride

1991 • 331 citations

A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines.

1990 • 302 citations

Insulin- and Mitogen-activated Protein Kinase-mediated Phosphorylation and Activation of Peroxisome Proliferator-activated Receptor γ

1996 • 272 citations

The Ah Receptor: A Regulator of the Biochemical and Toxicological Actions of Structurally Diverse Chemicals

1998 • 254 citations

Gender and risk of autoimmune diseases: possible role of estrogenic compounds.

1999 • 183 citations

Applications of gene arrays in environmental toxicology: fingerprints of gene regulation associated with cadmium chloride, benzo(a)pyrene, and trichloroethylene.

2001 • 161 citations

DNA microarray technology: the anticipated impact on the study of human disease

1999 • 160 citations

Development of a Toxicological Gene Array and Quantitative Assessment of This Technology

2000 • 125 citations

Lipid peroxidation in rats administrated with mercuric chloride

1996 • 112 citations

Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization

1999 • 112 citations

The Critical Role of Shc in Insulin-Like Growth Factor-I-Mediated Mitogenesis and Differentiation in 3T3-L1 Preadipocytes

2000 • 111 citations

Apoptosis—the mechanism of cell death in dimethylnitrosamine‐induced hepatotoxicity

1989 • 101 citations

Tissue injury and repair as parallel and opposing responses to CCl4 hepatotoxicity: a novel dose-response

1997 • 98 citations

Gene expression in liver after toxic injury: analysis of heat shock response and oxidative stress‐inducible genes

1997 • 87 citations

Toxicologists Brace for Genomics Revolution

2000 • 81 citations

cDNA cloning and mRNA expression of the six mouse insulin-like growth factor binding proteins

1994 • 79 citations

Molecular cloning of the peroxisome proliferator‐induced 46‐kDa cytosolic acyl‐CoA thioesterase from mouse and rat liver

1998 • 63 citations

Application of DNA arrays to toxicology.

1999 • 60 citations

Discrepancy between the Nephrotoxic Potencies of Cadmium-Metallothionein and Cadmium Chloride and the Renal Concentration of Cadmium in the Proximal Convoluted Tubules

1995 • 53 citations

Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration

1992 • 42 citations

p53-independent induction of p21WAF1/CIP1 expression in pericentral hepatocytes following carbon tetrachloride intoxication.

1997 • 38 citations

Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-β1 gene expression in the rat, Syrian hamster and guinea pig

2000 • 35 citations

Inhibition of P450 Cytochromes by Reactive Intermediates

1995 • 20 citations

Studies on the mechanism of dimethylnitrosamine-induced acute liver injury in mice

1997 • 18 citations

Molecular Dissection of Dimethylnitrosamine (DMN)-Induced Hepatotoxicity by mRNA Differential Display

1998 • 17 citations

The nephrotoxicity of single and multiple doses of aliphatic chlorinated hydrocarbon solvents in male mice

1972 • 17 citations

Comparative study on organ-specificity of tumorigenicity, mutagenicity and cell proliferative activity induced by dimethylnitrosamine in Big Blue® mice

1997 • 15 citations

Altered Hepatic mRNA Expression of Apoptotic Genes during Dimethylnitrosamine Exposure

2000 • 12 citations

Nephrotoxicity of bromobenzene in mice

1984 • 9 citations

[Organ cytotoxicity of selected polycyclic aromatic hydrocarbons in mice].

1997 • 2 citations