Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas

Caspases: Enemies Within

1998 • 6,923 citations

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Apoptotic Pathways

1998 • 1,193 citations

Bax and Adenine Nucleotide Translocator Cooperate in the Mitochondrial Control of Apoptosis

1998 • 1,183 citations

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

1995 • 1,171 citations

Molecular Pathogenesis of Cholestasis

1998 • 669 citations

Molecular Pathogenesis of Cholestasis

2004 • 622 citations

Regulated Targeting of BAX to Mitochondria

1998 • 617 citations

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas

1999 • 537 citations

A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation.

1998 • 523 citations

Ursodeoxycholic Acid May Inhibit Deoxycholic Acid-Induced Apoptosis by Modulating Mitochondrial Transmembrane Potential and Reactive Oxygen Species Production

1998 • 327 citations

Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes.

1994 • 270 citations

Mechanism of Cholestasis

1972 • 269 citations

Ursodeoxycholate (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: a mechanism of UDCA cytoprotection.

1995 • 231 citations

Mechanism of Cholestasis

1972 • 209 citations

Hepatic injury induced by bile salts: Correlation between biochemical and morphological events

1990 • 207 citations

Apoptosis is induced by transforming growth factor-beta 1 within 5 hours in regressing liver without significant fragmentation of the DNA.

1993 • 142 citations

Effect of tauroursodeoxycholic acid on bile-acid-induced apoptosis and cytolysis in rat hepatocytes

1998 • 139 citations

Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes

1998 • 119 citations

Apoptosis is induced by transforming growth factor-β1 within 5 hours in regressing liver without significant fragmentation of the DNA

1993 • 111 citations

Hepatocytes in the bile duct-ligated rat express Bcl-2

1997 • 77 citations

Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease-dependent pathway that does not activate cysteine protease P32.

1996 • 73 citations

Cholestasis confers resistance to the rat liver mitochondrial permeability transition

1998 • 64 citations