Coactivators for the Orphan Nuclear Receptor RORα

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Histone acetylation and transcriptional regulatory mechanisms

1998 • 1,793 citations

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

1996 • 1,095 citations

Nuclear receptor coactivators and corepressors.

1996 • 917 citations

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

1999 • 733 citations

Nuclear receptor coactivators

1997 • 720 citations

GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.

1996 • 702 citations

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

1995 • 627 citations

Hormone-Dependent Coactivator Binding to a Hydrophobic Cleft on Nuclear Receptors

1998 • 580 citations

GRIP1, a Transcriptional Coactivator for the AF-2 Transactivation Domain of Steroid, Thyroid, Retinoid, and Vitamin D Receptors

1997 • 572 citations

Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.

1997 • 534 citations

Disruption of the nuclear hormone receptor RORα in staggerer mice

1996 • 478 citations

Androstane metabolites bind to and deactivate the nuclear receptor CAR-β

1998 • 466 citations

The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion

1998 • 454 citations

Increasing the Complexity of Coactivation in Nuclear Receptor Signaling

1999 • 449 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

1995 • 431 citations

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

1995 • 429 citations

Nuclear receptor coactivators and corepressors

1996 • 414 citations

A novel protein complex that interacts with the vitamin D₃ receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system

1998 • 391 citations

Isolation and Characterization of PBP, a Protein That Interacts with Peroxisome Proliferator-activated Receptor

1997 • 340 citations

Orphan nuclear receptors--the first eight years.

1996 • 206 citations

The Monomer-Binding Orphan Receptor Rev-Erb Represses Transcription as a Dimer on a Novel Direct Repeat

1995 • 204 citations

Distinct Stages in Adipogenesis Revealed by Retinoid Inhibition of Differentiation after Induction of PPARγ

1996 • 181 citations

Orphan nuclear receptor RORα-deficient mice display the cerebellar defects of staggerer

1998 • 171 citations

Distinct steady–state nuclear receptor coregulator complexes exist in vivo

1998 • 165 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor

1995 • 154 citations

SRC-1 and GRIP1 Coactivate Transcription with Hepatocyte Nuclear Factor 4

1998 • 146 citations

Transcriptional Regulation of Apolipoprotein A-I Gene Expression by the Nuclear Receptor RORα

1997 • 129 citations

Transcriptional Activation and Repression by RORα, an Orphan Nuclear Receptor Required for Cerebellar Development

1997 • 95 citations

The Nonconserved Hinge Region and Distinct Amino-Terminal Domains of the RORα Orphan Nuclear Receptor Isoforms are Required for Proper DNA Bending and RORα-DNA Interactions

1995 • 92 citations

CREB-binding Protein Is a Transcriptional Coactivator for Hepatocyte Nuclear Factor-4 and Enhances Apolipoprotein Gene Expression

1999 • 88 citations

A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein

1997 • 78 citations

Competition between Thyroid Hormone Receptor-associated Protein (TRAP) 220 and Transcriptional Intermediary Factor (TIF) 2 for Binding to Nuclear Receptors

1999 • 76 citations

Differential Regulation of the N-myc Proto-Oncogene by RORα and RVR, Two Orphan Members of the Superfamily of Nuclear Hormone Receptors

1997 • 69 citations

Yeast hormone response element assays detect and characterize GRIP1 coactivator-dependent activation of transcription by thyroid and retinoid nuclear receptors

1997 • 62 citations

Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53

1997 • 56 citations

The unique C-termini of the thyroid hormone receptor variant, c-erbA alpha 2, and thyroid hormone receptor alpha 1 mediate different DNA-binding and heterodimerization properties.

1992 • 39 citations