Generation of lipid polarity in intestinal epithelial (Caco-2) cells: sphingolipid synthesis in the Golgi complex and sorting before vesicular traffic to the plasma membrane.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

1989 • 2,127 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

Lipid sorting in epithelial cells

1988 • 1,354 citations

Morphogenesis of the Polarized Epithelial Cell Phenotype

1989 • 1,087 citations

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

1989 • 1,027 citations

Cell Surface Polarity in Epithelia

1985 • 880 citations

Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells.

1985 • 497 citations

Lipid Traffic in Animal Cells

1989 • 468 citations

Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells.

1987 • 443 citations

Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus.

1990 • 369 citations

Epithelial properties of human colonic carcinoma cell line Caco-2: electrical parameters

1984 • 349 citations

A Vital Stain for the Golgi Apparatus

1985 • 344 citations

Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane.

1985 • 297 citations

Sorting of endogenous plasma membrane proteins occurs from two sites in cultured human intestinal epithelial cells (Caco-2)

1990 • 262 citations

Temperature-sensitive steps in the transport of secretory proteins through the Golgi complex in exocrine pancreatic cells.

1986 • 251 citations

Lipid dynamics and lipid-protein interactions in rat enterocyte basolateral and microvillus membranes

1980 • 243 citations

Reclustering of scattered Golgi elements occurs along microtubules.

1989 • 228 citations

Lipid recycling between the plasma membrane and intracellular compartments: transport and metabolism of fluorescent sphingomyelin analogues in cultured fibroblasts.

1989 • 221 citations

Biogenesis of intestinal plasma membrane: Posttranslational route and cleavage of sucrase—isomaltase

1979 • 216 citations

Vectorial targeting of apical and basolateral plasma membrane proteins in a human adenocarcinoma epithelial cell line.

1989 • 193 citations

Sphingomyelin is synthesized in the cis Golgi

1990 • 187 citations

Nocodazole, a microtubule-active drug, interferes with apical protein delivery in cultured intestinal epithelial cells (Caco-2).

1989 • 176 citations

Lipid components of two different regions of an intestinal epithelial cell membrane of mouse

1974 • 167 citations

Steady-state distribution and biogenesis of endogenous Madin-Darby canine kidney glycoproteins: evidence for intracellular sorting and polarized cell surface delivery.

1989 • 155 citations

Lipid composition of the isolated rat intestinal microvillus membrane

1968 • 150 citations

Topology of glucosylceramide synthesis in Golgi membranes from porcine submaxillary glands

1986 • 143 citations

Perforated MDCK cells support intracellular transport.

1987 • 129 citations

Release of putative exocytic transport vesicles from perforated MDCK cells.

1988 • 126 citations

Surface behaviour of gangliosides and related glycosphingolipids

1978 • 124 citations

Preparation and characterization of the lateral and basal plasma membranes of the rat intestinal epithelial cell

1972 • 123 citations

Lipid Transport During Mitosis

1989 • 119 citations

A specific sorting signal is not required for the polarized secretion of newly synthesized proteins from cultured intestinal epithelial cells.

1988 • 110 citations

Regulation of triglyceride-rich lipoprotein secretion by fatty acids in CaCo-2 cells

1988 • 89 citations

Biosynthesis of intestinal microvillar proteins. Evidence for an intracellular sorting taking place in, or shortly after, exit from the Golgi complex

1985 • 89 citations

Biogenesis of Endogenous Plasma Membrane Proteins in Epithelial Cells

1989 • 84 citations

Synthesis of membrane glycoproteins in rat small-intestinal villus cells. Redistribution of <scp>l</scp>-[1,5,6-3H]-fucose-labelled membrane glycoproteins among Golgi, lateral basal and microvillus membranes in vivo

1979 • 78 citations

Intestinal aminooligopeptidase. In vivo synthesis on intracellular membranes of rat jejunum.

1982 • 74 citations

Salvage of glucosylceramide by recycling after internalization along the pathway of receptor-mediated endocytosis.

1989 • 66 citations

Evidence for the transit of aminopeptidase N through the basolateral membrane before it reaches the brush border of enterocytes

1987 • 65 citations

Immuno-electronmicroscopical localization of a microvillus membrane disaccharidase in the human small-intestinal epithelium with monoclonal antibodies.

1985 • 51 citations

Regulated vectorial secretion of cholesteryl ester transfer protein (LTP-I) by the CaCo-2 model of human enterocyte epithelium.

1988 • 49 citations

Immunomicroscopic localization of aminopeptidase N in the pig enterocyte. Implications for the route of intracellular transport.

1987 • 44 citations

Localization of sucrase-isomaltase in the rat enterocyte

1987 • 38 citations

Basolateral secretion of kappa light chain in the polarised epithelial cell line, Caco-2

1989 • 37 citations

The subcellular localization of the glycosphingolipids in the epithelial cells of rat small intestine

1983 • 26 citations

Enzymatic glucosylation of dolichol monophosphate and transfer of glucose from isolated dolichyl‐<scp>D</scp>‐glucosyl phosphate to ceramides by BHK‐21 cell microsemes

1984 • 14 citations