Neutralizing Anti‐p21^ras Fabs Suppress Rat Sympathetic Neuron Survival Induced by NGF, LIF, CNTF and cAMP

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

1993 • 1,077 citations

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1993 • 1,026 citations

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

1993 • 972 citations

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation.

1988 • 909 citations

CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130

1992 • 693 citations

LIFRβ and gp130 as Heterodimerizing Signal Transducers of the Tripartite CNTF Receptor

1993 • 632 citations

The Receptor for Ciliary Neurotrophic Factor

1991 • 604 citations

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

1993 • 587 citations

Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130.

1991 • 587 citations

The Cholinergic Neuronal Differentiation Factor from Heart Cells Is Identical to Leukemia Inhibitory Factor

1989 • 557 citations

Purification of the Chick Eye Ciliary Neuronotrophic Factor

1984 • 519 citations

Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture.

1989 • 347 citations

cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor.

1988 • 312 citations

Purification and partial characterization of a cholinergic neuronal differentiation factor.

1985 • 211 citations

The Death Programme in Cultured Sympathetic Neurones Can Be Suppressed at the Posttranslational Level by Nerve Growth Factor, Cyclic AMP, and Depolarization

1991 • 202 citations

ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons

1989 • 192 citations

Leukemia Inhibitory Factor and Interleukin-6 Trigger the Same Immediate Early Response, Including Tyrosine Phosphorylation, upon Induction of Myeloid Leukemia Differentiation

1991 • 186 citations

Differentiation factors, including nerve growth factor, fibroblast growth factor, and interleukin-6, induce an accumulation of an active Ras.GTP complex in rat pheochromocytoma PC12 cells.

1992 • 185 citations

Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal

1994 • 184 citations

Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures.

1991 • 182 citations

Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures

1991 • 164 citations

Effects of ciliary neurotrophic factor (CNTF) and depolarization on neuropeptide expression in cultured sympathetic neurons

1992 • 155 citations

Reconstitution of the response to leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in hepatoma cells.

1993 • 135 citations

Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability

1993 • 124 citations

Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons.

1993 • 122 citations

Nerve growth factor acts through cAMP-dependent protein kinase to increase the number of sodium channels in PC12 cells

1990 • 120 citations

Cytokine-induced programmed death of cultured sympathetic neurons

1993 • 102 citations

Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation.

1991 • 95 citations

Inhibition of Thyrotropin-Stimulated DNA Synthesis by Microinjection of Inhibitors of Cellular Ras and Cyclic AMP-Dependent Protein Kinase

1993 • 67 citations

Postnatal development of survival responsiveness in rat sympathetic neurons to leukemia inhibitory factor and ciliary neurotrophic factor

1994 • 60 citations

Apoptosis is induced in post-mitotic rat sympathetic neurons by arabinosides and topoisomerase II inhibitors in the presence of NGF

1994 • 60 citations

Ectopic trkA expression mediates a NGF survival response in NGF-independent sensory neurons but not in parasympathetic neurons.

1993 • 53 citations

Role of protein tyrosine phosphorylation in the NGF response

1989 • 52 citations

Further Studies of the Distribution of CDF/LIF mRNA

2007 • 47 citations

Role of Ras in signal transduction from the nerve growth factor receptor: relationship to protein kinase C, calcium and cyclic AMP.

1992 • 41 citations

Effects of Ciliary Neurotrophic Factor on the Survival and Response to Nerve Growth Factor of Cultured Rat Sympathetic Neurons

1994 • 28 citations

Nerve Growth Factor is Required for Induction of c‐Fos Immunoreactivity by Serum, Depolarization, Cyclic AMP or Trauma in Cultured Rat Sympathetic Neurons

1991 • 25 citations

CDF/LIF selectively increases c-fos and jun-B transcripts in sympathetic neurons

1991 • 21 citations

Mediators of nerve growth factor action in cultured rat superior cervical ganglion neurones

1991 • 9 citations