Leukemia Inhibitory Factor and Interleukin-6 Trigger the Same Immediate Early Response, Including Tyrosine Phosphorylation, upon Induction of Myeloid Leukemia Differentiation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Interleukin-6: An Overview

1990 • 1,910 citations

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.

1987 • 1,667 citations

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1989 • 1,411 citations

Molecular cloning and expression of an IL-6 signal transducer, gp130

1990 • 1,307 citations

CYTOKINES: COORDINATORS OF IMMUNE AND INFLAMMATORY RESPONSES

1990 • 1,304 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Cloning and Expression of the Human Interleukin-6 (BSF-2/IFNβ 2) Receptor

1988 • 1,063 citations

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation.

1981 • 585 citations

Complexity of the early genetic response to growth factors in mouse fibroblasts.

1988 • 579 citations

Molecular Regulation of B Lymphocyte Response

1988 • 579 citations

Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF).

1987 • 567 citations

The Cholinergic Neuronal Differentiation Factor from Heart Cells Is Identical to Leukemia Inhibitory Factor

1989 • 557 citations

A novel family of growth factor receptors: A common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor β-chain

1989 • 551 citations

A new cytokine receptor superfamily

1990 • 506 citations

Interleukin 6: A Multifunctional Cytokine Regulating Immune Reactions and the Acute Phase Protein Response

1990 • 483 citations

Human interleukin 6 is a direct promoter of maturation of megakaryocytes in vitro.

1989 • 430 citations

Induction of Neuronal Differentiation in PC12 Cells by B-Cell Stimulatory Factor 2/Interleukin 6

1988 • 402 citations

Human actin genes are single copy for alpha-skeletal and alpha-cardiac actin but multicopy for beta- and gamma-cytoskeletal genes: 3' untranslated regions are isotype specific but are conserved in evolution.

1983 • 393 citations

B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes.

1988 • 382 citations

mRNA decay: Finding the right targets

1989 • 318 citations

Recombinant human B cell stimulatory factor 2 (BSF‐2/IFN‐β2) regulates β‐fibrinogen and albumin mRNA levels in Fao‐9 cells

1987 • 299 citations

Oncogenes, Growth Factors, and Signal Transduction

1989 • 296 citations

Tyrphostins Inhibit Epidermal Growth Factor (EGF)-Receptor Tyrosine Kinase Activity in Living Cells and EGF-Stimulated Cell Proliferation

1989 • 286 citations

Hepatocyte-stimulating factor III shares structural and functional identity with leukemia-inhibitory factor.

1989 • 272 citations

Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6.

1990 • 258 citations

Interleukin-6 as a neurotrophic factor for promoting the survival of cultured basal forebrain cholinergic neurons from postnatal rats

1989 • 252 citations

T cell growth and differentiation induced by interleukin-HP1/IL-6, the murine hybridoma/plasmacytoma growth factor.

1988 • 244 citations

Effects of injected leukemia inhibitory factor on hematopoietic and other tissues in mice

1990 • 226 citations

The myeloid blood cell differentiation-inducing protein MGI-2A is interleukin-6

1988 • 198 citations

Multiple biological activities are expressed by a mouse interleukin 6 cDNA clone isolated from bone marrow stromal cells.

1988 • 174 citations

Complexity of the Early Genetic Response to Growth Factors in Mouse Fibroblasts

1988 • 159 citations

Interleukin-6 signals activating junB and TIS11 gene transcription in a B-cell hybridoma.

1991 • 147 citations

Interleukin-6: Molecular Pathophysiology

1990 • 146 citations

Specific binding of murine leukemia inhibitory factor to normal and leukemic monocytic cells.

1988 • 130 citations

Tyrosine phosphorylation of a gap junction protein correlates with inhibition of cell-to-cell communication.

1990 • 112 citations

Complexity of the immediate early response of myeloid cells to terminal differentiation and growth arrest includes ICAM-1, Jun-B and histone variants.

1990 • 97 citations

Sequence of MyD116 cDNA: a novel myeloid differentiation primary response gene induced by IL6

1990 • 88 citations

IL-6 is a differentiation factor for M1 and WEHI-3B myeloid leukemic cells.

1989 • 78 citations

A simplification of the nuclear run-off transcription assay.

1989 • 75 citations

Localization of tyrosine kinase-coding region in v-abl oncogene by the expression of v-abl-encoded proteins in bacteria.

1985 • 70 citations

Proto-oncogene expression and dissection of the myeloid growth to differentiation developmental cascade.

1989 • 62 citations

Regulation and role of different macrophage‐ and granulocyte‐inducing proteins in normal and leukemic myeloid cells

1982 • 44 citations

Co-regulation of type C RNA virus production and cell differentiation in myeloid leukemic cells

1978 • 35 citations

Inhibition of differentiation and affinity purification with a monoclonal antibody to a myeloid cell differentiation-inducing protein

1988 • 29 citations

Interleukin-6 Signals Activating junB and TIS11 Gene Transcription in a B-Cell Hybridoma

1991 • 24 citations

Interleukin‐6

1989 • 19 citations

Structural similarity between a primitive chordate membrane heterodimer and lymphocyte antigen receptors

1990 • 9 citations