Culture of Purified Stem Cells from Fetal Liver Results in Loss of In Vivo Repopulating Potential

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

1988 • 2,004 citations

Role of insulin-like growth factors in embryonic and postnatal growth

1993 • 644 citations

The ins and outs of fibroblast growth factors

1994 • 535 citations

Identification and characterization of an inhibitor of haemopoietic stem cell proliferation

1990 • 470 citations

A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis.

1987 • 345 citations

Lymphoid and myeloid differentiation of single human CD34+, HLA-DR+, CD38- hematopoietic stem cells

1994 • 314 citations

Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells

1993 • 296 citations

Membrane-bound Steel factor induces more persistent tyrosine kinase activation and longer life span of c-kit gene-encoded protein than its soluble form

1995 • 268 citations

Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture.

1991 • 234 citations

Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow.

1992 • 231 citations

Limiting dilution assays

1987 • 195 citations

RETRACTED ARTICLE: Formation of haematopoietic microenvironment and haematopoietic stem cells from single human bone marrow stem cells

1992 • 183 citations

Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level.

1992 • 174 citations

Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture

1992 • 167 citations

Bone marrow transplantation with interleukin-1 plus kit-ligand ex vivo expanded bone marrow accelerates hematopoietic reconstitution in mice without the loss of stem cell lineage and proliferative potential

1993 • 166 citations

Autografting with cultured marrow in chronic myeloid leukemia: results of a pilot study [see comments]

1994 • 153 citations

Proliferation of totipotent hematopoietic stem cells in vitro with retention of long-term competitive in vivo reconstituting ability.

1992 • 144 citations

Maintenance of transplantation potential in ex vivo expanded CD34(+)- selected human peripheral blood progenitor cells

1994 • 139 citations

Amplification of Sca-1+ Lin-WGA+ cells in serum-free cultures containing steel factor, interleukin-6, and erythropoietin with maintenance of cells with long-term in vivo reconstituting potential

1994 • 139 citations

Stem cell factor enhances the survival but not the self-renewal of murine hematopoietic long-term repopulating cells

1994 • 137 citations

Expansion of Hematopoietic Progenitor Cell Populations in Stirred Suspension Bioreactors of Normal Human Bone Marrow Cells

1994 • 131 citations

Characterization and purification of a primitive hematopoietic cell type in adult mouse marrow capable of lymphomyeloid differentiation in long-term marrow "switch" cultures

1995 • 131 citations

Autografting with cultured marrow in chronic myeloid leukemia: results of a pilot study [see comments]

1994 • 121 citations

Synergistic interactions between interleukin-11 and interleukin-4 in support of proliferation of primitive hematopoietic progenitors of mice

1991 • 118 citations

Competitive in vivo proliferation of foetal and adult haematopoietic cells in lethally irradiated mice

1972 • 106 citations

Expansion in vitro of retrovirally marked totipotent hematopoietic stem cells

1990 • 100 citations

Maintenance of high levels of pluripotent hematopoietic stem cells in vitro: effect of stromal cells and c-kit

1993 • 92 citations

Maintenance of high levels of pluripotent hematopoietic stem cells in vitro: effect of stromal cells and c-kit

1993 • 70 citations

Synergistic effects of interleukin-11 with other growth factors on the expansion of murine hematopoietic progenitors and maintenance of stem cells in liquid culture.

1994 • 60 citations

Phenotypic heterogeneity of primitive leukemic hematopoietic cells in patients with chronic myeloid leukemia

1992 • 56 citations

Hematopoietic stem cells: Inferences from in vivo assays

1997 • 51 citations

Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivo.

1991 • 50 citations

Graft-Versus-Host Disease

1991 • 38 citations

Erythropoietin as a Mitogen for Fetal Liver Stromal Cells Which Support Erythropoiesis

1993 • 31 citations

New strategies for the treatment of chronic myeloid leukemia [editorial; comment]

1994 • 23 citations

Insulin-like Growth Factors Promote DNA Synthesis and Support Cell Viability in Fetal Hemopoietic Tissue by Paracrine Mechanisms

1990 • 16 citations