Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivo.

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

1988 • 2,004 citations

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

1988 • 1,848 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

A safe packaging line for gene transfer: separating viral genes on two different plasmids

1988 • 1,118 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice

1985 • 663 citations

FVB/N: an inbred mouse strain preferable for transgenic analyses.

1991 • 600 citations

Lineage-specific expression of a human β-globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cells

1988 • 341 citations

Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells.

1989 • 316 citations

Oncogenesis of the Lens in Transgenic Mice

1987 • 202 citations

A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells.

1989 • 153 citations

Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells.

1989 • 133 citations

Infection efficiency of T lymphocytes with amphotropic retroviral vectors is cell cycle dependent

1989 • 129 citations

Expression of human adenosine deaminase in murine hematopoietic cells.

1988 • 112 citations

Expression of human adenosine deaminase in mice reconstituted with retrovirus-transduced hematopoietic stem cells.

1990 • 105 citations

[67] Adenosine deaminase from human erythrocytes

1978 • 74 citations

Human adenosine deaminase expression in mice

1990 • 53 citations

Murine leukemia inhibitory factor enhances retroviral-vector infection efficiency of hematopoietic progenitors

1990 • 50 citations

Insertional inactivation of the downless gene in a family of transgenic mice.

1989 • 36 citations

A Majority of Mice Show Long-Term Expression of a Human ß-Globin Gene after Retrovirus Transfer into Hematopoietic Stem Cells

1989 • 32 citations

Expression of Human Adenosine Deaminase in Murine Hematopoietic Cells

1988 • 27 citations

Mock retroviral infection alters the developmental potential of murine bone marrow stem cells.

1989 • 14 citations

Mock Retroviral Infection Alters the Developmental Potential of Murine Bone Marrow Stem Cells

1989 • 5 citations

Potential applications of gene therapy

1989 • 2 citations