Expansion in vitro of retrovirally marked totipotent hematopoietic stem cells

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1987 • 2,368 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS

1964 • 889 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins

1984 • 719 citations

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice

1985 • 663 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

Clonal and systemic analysis of long-term hematopoiesis in the mouse.

1990 • 577 citations

The identification in adult bone marrow of pluripotent and restricted stem cells of the myeloid and lymphoid systems

1977 • 563 citations

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

1984 • 451 citations

CYTOLOGICAL EVIDENCE FOR A RELATIONSHIP BETWEEN NORMAL HEMATOPOIETIC COLONY-FORMING CELLS AND CELLS OF THE LYMPHOID SYSTEM

1968 • 441 citations

Human marrow cells capable of erythropoietic differentiation in vitro: definition of three erythroid colony responses

1977 • 278 citations

Ontogeny of the T-cell antigen receptor within the thymus

1985 • 250 citations

Y-encoded, species-specific DNA in mice: Evidence that the Y chromosome exists in two polymorphic forms in inbred strains

1984 • 233 citations

Clonal fluctuation within the haematopoietic system of mice reconstituted with retrovirus-infected stem cells.

1987 • 168 citations

Monoclonal derivation of mouse myeloid and lymphoid lineages from totipotent hematopoietic stem cells experimentally engrafted in fetal hosts.

1984 • 117 citations

Clonal contributions of small numbers of retrovirally marked hematopoietic stem cells engrafted in unirradiated neonatal W/Wv mice.

1989 • 116 citations

Retrovirus-mediated gene transfer to purified hemopoietic stem cells with long-term lympho-myelopoietic repopulating ability.

1989 • 98 citations

High-efficiency gene transfer to human hematopoietic cells maintained in long-term marrow culture [see comments]

1989 • 83 citations

Cell lineages in hematopoietic neoplasia studied with glucose-6-phosphate dehydrogenase cell markers

1982 • 82 citations

In vitro differentiation of B lymphocytes from primitive hemopoietic precursors present in long-term bone marrow cultures.

1986 • 73 citations

Differentiation of Rosette-Forming Cells from Myeloid Stem Cells

1970 • 73 citations

In vitro studies on lymphocyte differentiation. I. Long term in vitro culture of cells giving rise to functional lymphocytes in irradiated mice.

1978 • 68 citations

Use of scid mice to identify and quantitate lymphoid-restricted stem cells in long-term bone marrow cultures

1989 • 47 citations

Human marrow cells capable of erythropoietic differentiation in vitro: definition of three erythroid colony responses

1977 • 30 citations

Lymphoid differentiation of the hematopoietic stem cell that reconstitutes total erythropoiesis of a genetically anemic W/Wv mouse

1989 • 21 citations

Use of scid mice to identify and quantitate lymphoid-restricted stem cells in long-term bone marrow cultures

1989 • 8 citations

Erythropoietic repopulating ability of stem cells from long-term marrow culture

1987 • 6 citations

Lymphoid differentiation of the hematopoietic stem cell that reconstitutes total erythropoiesis of a genetically anemic W/Wv mouse

1989 • 2 citations