An Endocytosed TGN38 Chimeric Protein Is Delivered to the TGN after Trafficking through the Endocytic Recycling Compartment in CHO Cells

Rab11 regulates recycling through the pericentriolar recycling endosome.

1996 • 1,293 citations

Endocytosis

1997 • 1,263 citations

STRUCTURE AND FUNCTION OF THE MANNOSE 6-PHOSPHATE/INSULINLIKE GROWTH FACTOR II RECEPTORS

1992 • 1,056 citations

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

1991 • 832 citations

Membrane transport in the endocytic pathway

1995 • 644 citations

Segregation of transferrin to a mildly acidic (pH 6.5) para-golgi compartment in the recycling pathway

1984 • 586 citations

Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process.

1993 • 516 citations

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface.

1994 • 494 citations

Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

1987 • 479 citations

The endocytotic rate constant. A cellular parameter for quantitating receptor-mediated endocytosis.

1982 • 399 citations

Brefeldin A causes a microtubule-mediated fusion of the trans-Golgi network and early endosomes

1991 • 378 citations

Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38)

1990 • 355 citations

Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome.

1989 • 330 citations

Cholesterol-dependent retention of GPI-anchored proteins in endosomes

1998 • 313 citations

Molecular trapping of a fluorescent ceramide analogue at the Golgi apparatus of fixed cells: interaction with endogenous lipids provides a trans-Golgi marker for both light and electron microscopy.

1989 • 258 citations

Two syntaxin homologues in the TGN/endosomal system of yeast

1998 • 258 citations

Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence.

1993 • 258 citations

TGN38 is maintained in the trans-Golgi network by a tyrosine-containing motif in the cytoplasmic domain.

1993 • 231 citations

Intracellular movement of cell surface receptors after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cells.

1985 • 229 citations

The cytoplasmic tail of the mannose 6-phosphate/insulin-like growth factor-II receptor has two signals for lysosomal enzyme sorting in the Golgi.

1992 • 225 citations

Rab11, a small GTPase associated with both constitutive and regulated secretory pathways in PC12 cells

1993 • 219 citations

Exocytosis of pinocytosed fluid in cultured cells: kinetic evidence for rapid turnover and compartmentation.

1981 • 215 citations

An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface.

1995 • 215 citations

Quantification of low density lipoprotein and transferrin endocytic sorting in HEp2 cells using confocal microscopy

1994 • 212 citations

Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor.

1987 • 208 citations

A His-Leu-Leu sequence near the carboxyl terminus of the cytoplasmic domain of the cation-dependent mannose 6-phosphate receptor is necessary for the lysosomal enzyme sorting function.

1992 • 205 citations

Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes

1992 • 187 citations

Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail.

1995 • 184 citations

The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system.

1994 • 169 citations

Functional expression of furin demonstrating its intracellular localization and endoprotease activity for processing of proalbumin and complement pro-C3.

1991 • 162 citations

Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment.

1995 • 153 citations

Endocytosis and Lysosomal Targeting of Epidermal Growth Factor Receptors Are Mediated by Distinct Sequences Independent of the Tyrosine Kinase Domain

1995 • 151 citations

Low density lipoprotein receptor and cation-independent mannose 6-phosphate receptor are transported from the cell surface to the Golgi apparatus at equal rates in PC12 cells

1992 • 147 citations

TGN38/41 recycles between the cell surface and the TGN: brefeldin A affects its rate of return to the TGN.

1993 • 143 citations

The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network.

1994 • 134 citations

Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain.

1990 • 130 citations

Multiple pathways of exocytosis, endocytosis, and membrane recycling: validation of a Golgi route.

1983 • 126 citations

The SXYQRL sequence in the cytoplasmic domain of TGN38 plays a major role in trans-Golgi network localization.

1993 • 121 citations

Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells.

1995 • 116 citations

The trans-Golgi network can be dissected structurally and functionally from the cisternae of the Golgi complex by brefeldin A.

1992 • 114 citations

Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells.

1989 • 114 citations

TGN38 and its orthologues: roles in post-TGN vesicle formation and maintenance of TGN morphology

1997 • 114 citations

Kinetics of binding, endocytosis, and recycling of EGF receptor mutants

1992 • 100 citations

Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo.

1989 • 88 citations

The End2 mutation in CHO cells slows the exit of transferrin receptors from the recycling compartment but bulk membrane recycling is unaffected

1993 • 86 citations

Intracellular fusion of sequentially formed endocytic compartments.

1988 • 85 citations

Insulin stimulation of GLUT-4 translocation: a model for regulated recycling

1994 • 78 citations

Transport of surface mannose 6-phosphate receptor to the Golgi complex in cultured human cells

1989 • 77 citations

TGN38 recycles basolaterally in polarized Madin-Darby canine kidney cells.

1994 • 56 citations

TGN38/41: a molecule on the move

1993 • 56 citations

Transferrin receptor containing the SDYQRL motif of TGN38 causes a reorganization of the recycling compartment but is not targeted to the TGN.

1996 • 35 citations

An electron microscopic study of TGN38/41 dynamics

1993 • 22 citations