Transport of surface mannose 6-phosphate receptor to the Golgi complex in cultured human cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

LYSOSOMAL ENZYMES AND THEIR RECEPTORS

1986 • 915 citations

Insulin-like growth factor II receptor as a multifunctional binding protein

1987 • 858 citations

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1988 • 846 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Reduced temperature prevents transfer of a membrane glycoprotein to the cell surface but does not prevent terminal glycosylation

1983 • 504 citations

Trafficking of lysosomal enzymes ¹

1987 • 497 citations

Low temperature selectively inhibits fusion between pinocytic vesicles and lysosomes during heterophagy of 125I-asialofetuin by the perfused rat liver.

1980 • 451 citations

Demonstration of an extensive trans-tubular network continuous with the Golgi apparatus stack that may function in glycosylation

1985 • 448 citations

Penetration of semliki forest virus from acidic prelysosomal vacuoles

1983 • 411 citations

A Single Receptor Binds Both Insulin-Like Growth Factor II and Mannose-6-Phosphate

1988 • 363 citations

Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver

1984 • 359 citations

The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis Golgi cisternae

1984 • 291 citations

Mannose-6-phosphate receptors for lysosomal enzymes cycle between the Golgi complex and endosomes.

1986 • 270 citations

Evidence for extensive subcellular organization of asparagine-linked oligosaccharide processing and lysosomal enzyme phosphorylation.

1983 • 270 citations

Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatus.

1988 • 263 citations

The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells.

1988 • 244 citations

Intracellular movement of cell surface receptors after endocytosis: resialylation of asialo-transferrin receptor in human erythroleukemia cells.

1985 • 229 citations

Cloning and sequence analysis of the cation-independent mannose 6-phosphate receptor.

1988 • 210 citations

The cation-independent mannose 6-phosphate receptor binds insulin-like growth factor II.

1988 • 199 citations

Purification and characterization of a cation-dependent mannose 6-phosphate receptor from murine P388D1 macrophages and bovine liver.

1985 • 193 citations

Biochemical evidence that the type II insulin-like growth factor receptor is identical to the cation-independent mannose 6-phosphate receptor.

1988 • 190 citations

Selective recycling of the mannose 6-phosphate/IGF-II receptor to the trans Golgi network in vitro

1988 • 177 citations

Characterization of a membrane-associated receptor from bovine liver that binds phosphomannosyl residues of bovine testicular beta-galactosidase.

1981 • 176 citations

Differential subcompartmentation of terminal glycosylation in the Golgi apparatus of intestinal absorptive and goblet cells.

1986 • 172 citations

Biosynthesis and turnover of the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

1983 • 169 citations

Ultrastructural localization of the mannose 6-phosphate receptor in rat liver.

1984 • 162 citations

46 kd mannose 6-phosphate receptor: Cloning, expression, and homology to the 215 kd mannose 6-phosphate receptor

1987 • 150 citations

Beta-glucuronidase binding to human fibroblast membrane receptors.

1980 • 143 citations

Light and electron microscopic demonstration of sialic acid residues with the lectin from Limax flavus: a cytochemical affinity technique with the use of fetuin-gold complexes.

1984 • 134 citations

Cloning of the bovine 215-kDa cation-independent mannose 6-phosphate receptor.

1987 • 132 citations

Lysosomal enzyme binding to mouse P388D1 macrophage membranes lacking the 215-kDa mannose 6-phosphate receptor: evidence for the existence of a second mannose 6-phosphate receptor.

1985 • 123 citations

Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes?

1987 • 123 citations

Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells

1979 • 120 citations

Mutant Chinese hamster ovary cells pleiotropically defective in receptor-mediated endocytosis.

1983 • 116 citations

Redistribution of mannose-6-phosphate receptors induced by tunicamycin and chloroquine.

1984 • 114 citations

Antibody to mannose 6-phosphate specific receptor induces receptor deficiency in human fibroblasts.

1984 • 104 citations

Membrane traffic in animal cells: cellular glycoproteins return to the site of Golgi mannosidase I.

1986 • 103 citations

The site of incorporation of sialic acid residues into glycoproteins and the subsequent fates of these molecules in various rat and mouse cell types as shown by radioautography after injection of [3H]N-acetylmannosamine. I. Observations in hepatocytes.

1981 • 99 citations

Cloning of a cDNA encoding the human cation-dependent mannose 6-phosphate-specific receptor.

1987 • 95 citations

The type II insulin-like growth factor receptor is internalized and recycles in the absence of ligand.

1986 • 87 citations

Assay and purification of a solubilized membrane receptor that binds the lysosomal enzyme α-l-iduronidase

1982 • 79 citations

The mannose 6‐phosphate receptor: function, biosynthesis and translocation

1984 • 73 citations

Mannose 6-phosphate receptors and their role in targeting proteins to lysosomes

1988 • 69 citations

Internalization of blocking antibodies against mannose-6-phosphate specific receptors.

1985 • 68 citations

Identification of mannose 6-phosphate receptors in rabbit alveolar macrophages.

1984 • 67 citations

Lysosomal enzyme precursors in coated vesicles derived from the exocytic and endocytic pathways.

1987 • 66 citations

Accumulation of coated vesicles bearing mannose 6-phosphate receptors for lysosomal enzymes in the Golgi region of I-cell fibroblasts.

1984 • 65 citations

Ultrastructural immunocytochemical localization of the phosphomannosyl receptor in Chinese hamster ovary (CHO) cells.

1983 • 61 citations

The mannose 6-phosphate receptor of Chinese hamster ovary cells. Compartmentalization of acid hydrolases in mutants with altered receptors.

1981 • 61 citations

The endosomal concentration of a mannose 6-phosphate receptor is unchanged in the absence of ligand synthesis.

1987 • 59 citations

Cathepsin D precursors in clathrin-coated organelles from human fibroblasts.

1985 • 55 citations

The distribution of 215-kilodalton mannose 6-phosphate receptors within cis (heavy) and trans (light) Golgi subfractions varies in different cell types.

1987 • 52 citations

[53] β-Galactosidase from bovine testes

1978 • 48 citations