Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

1985 • 1,585 citations

THE ULTRASTRUCTURAL BASIS OF CAPILLARY PERMEABILITY STUDIED WITH PEROXIDASE AS A TRACER

1967 • 1,495 citations

RECEPTORS FOR EPIDERMAL GROWTH FACTOR AND OTHER POLYPEPTIDE MITOGENS

1987 • 1,274 citations

CORRELATED MORPHOMETRIC AND BIOCHEMICAL STUDIES ON THE LIVER CELL

1969 • 1,134 citations

Recycling receptors: The round-trip itinerary of migrant membrane proteins

1983 • 780 citations

Galloylglucoses of low molecular weight as mordant in electron microscopy. I. Procedure, and evidence for mordanting effect.

1976 • 598 citations

Isolation of the Insulin Receptor of Liver and Fat-Cell Membranes

1972 • 397 citations

Receptors compete for adaptors found in plasma membrane coated pits.

1988 • 366 citations

Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts.

1984 • 357 citations

Isolation of rat hepatocyte plasma membranes. I. Presence of the three major domains.

1983 • 306 citations

Living with Clathrin: Its Role in Intracellular Membrane Traffic

1988 • 304 citations

Receptor-mediated endocytosis of epidermal growth factor by hepatocytes in the perfused rat liver: ligand and receptor dynamics.

1984 • 265 citations

Receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes: receptor pathway.

1986 • 217 citations

Peptide Hormone-Induced Receptor Mobility, Aggregation, and Internalization

1981 • 207 citations

ELECTRON MICROSCOPIC EXAMINATION OF SUBCELLULAR FRACTIONS

1967 • 189 citations

Uptake of Insulin and Other Ligands into Receptor-Rich Endocytic Components of Target Cells: The Endosomal Apparatus

1985 • 163 citations

Internalization of functional epidermal growth factor:receptor/kinase complexes in A-431 cells.

1985 • 128 citations

Internalization and Activation of the Rat Liver Insulin Receptor Kinase in vivo

1989 • 116 citations

Characterization of rat liver endosomal fractions. In vivo activation of insulin-stimulable receptor kinase in these structures.

1986 • 107 citations

Galactose transfer to endogenous acceptors within Golgi fractions of rat liver.

1982 • 105 citations

The endocytosis of epidermal growth factor in A431 cells: A pH of microenvironment and the dynamics of receptor complex dissociation

1988 • 88 citations

Characterization and Regulation of Epidermal Growth Factor Receptors in Human Placental Cell Cultures *

1984 • 87 citations

Direct visualization of the phosphorylated epidermal growth factor receptor during its internalization in A-431 cells.

1987 • 85 citations

Ligand-induced translocation of insulin receptors in intact rat liver.

1982 • 85 citations

Epidermal growth factor receptor kinase translocation and activation in vivo.

1986 • 81 citations

Perinuclear location and recycling of epidermal growth factor receptor kinase: immunofluorescent visualization using antibodies directed to kinase and extracellular domains.

1986 • 78 citations

Intracellular processing of epidermal growth factor and its effect on ligand-receptor interactions.

1985 • 71 citations

Proteolytic processing of epidermal growth factor within endosomes

1987 • 50 citations

Recycling of epidermal growth factor in a human pancreatic carcinoma cell line.

1985 • 44 citations

Accumulation of epidermal growth factor within cells does not depend on receptor recycling

1980 • 36 citations

Binding and Internalization of Epidermal Growth Factor in Human Term Placental Cells in Culture*

1986 • 35 citations

Terminal glycosylation in rat hepatic Golgi fractions: heterogeneous locations for sialic acid and galactose acceptors and their transferases

1985 • 25 citations

Binding characteristics of epidermal growth factor receptors in male and female rat liver cell membrane preparations

1985 • 20 citations

EGF induces receptor down‐regulation with no receptor recycling in KB cells

1985 • 20 citations

Recycling of epidermal growth factor in A431 cells

1987 • 16 citations

Subcellular distribution of acid NADPase activity within the parenchymal cells of rat liver.

1986 • 11 citations