A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

Basic local alignment search tool

1990 • 87,358 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

A polymorphic DNA marker genetically linked to Huntington's disease

1983 • 2,329 citations

Type 1 Neurofibromatosis Gene: Identification of a Large Transcript Disrupted in Three NF1 Patients

1990 • 1,471 citations

Von Recklinghausen Neurofibromatosis

1981 • 1,336 citations

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

1990 • 1,107 citations

The neurofibromatosis type 1 gene encodes a protein related to GAP

1990 • 1,099 citations

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus

1990 • 1,085 citations

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

1990 • 834 citations

Cytoskeleton—Plasma Membrane Interactions

1992 • 792 citations

Neurofibromatosis, Phenotype, Natural History, and Pathogenesis

1992 • 789 citations

Chromosomal Imbalance in the Aniridia-Wilms' Tumor Association: 11p Interstitial Deletion

1978 • 726 citations

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

1992 • 648 citations

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

1992 • 583 citations

Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma

1986 • 524 citations

Genetic linkage of bilateral acoustic neurofibromatosis to a DNA marker on chromosome 22

1987 • 470 citations

A genetic study of type 2 neurofibromatosis in the United Kingdom. I. Prevalence, mutation rate, fitness, and confirmation of maternal transmission effect on severity.

1992 • 452 citations

Neurofibromatosis 2

1988 • 438 citations

Exon amplification: a strategy to isolate mammalian genes based on RNA splicing.

1991 • 425 citations

Neurofibromatosis 1 (Recklinghausen Disease) and Neurofibromatosis 2 (Bilateral Acoustic Neurofibromatosis)

1990 • 415 citations

Aniridia-Wilms’ tumor association: evidence for specific deletion of 11p13

1979 • 404 citations

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor.

1989 • 385 citations

Use of cyclosporin a in establishing epstein-barr virus-transformed human lymphoblastoid cell lines

1984 • 355 citations

A survey of expressed genes in Caenorhabditis elegans

1992 • 355 citations

A gene family consisting of ezrin, radixin and moesin Its specific localization at actin filament/plasma membrane association sites

1992 • 334 citations

Molecular genetic approach to human meningioma: loss of genes on chromosome 22.

1987 • 322 citations

Sequence and domain structure of talin

1990 • 314 citations

Common Pathogenetic Mechanism for Three Tumor Types in Bilateral Acoustic Neurofibromatosis

1987 • 259 citations

cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1.

1989 • 253 citations

Moesin: a member of the protein 4.1-talin-ezrin family of proteins.

1991 • 250 citations

Molecular detection of deletions involving band q14 of chromosome 13 in retinoblastomas.

1986 • 240 citations

The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it.

1988 • 234 citations

Temperature-sensitive mutations in the III–IV cytoplasmic loop region of the skeletal muscle sodium channel gene in paramyotonia congenita

1992 • 219 citations

A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterization.

1989 • 211 citations

Deficiency of skeletal membrane protein band 4.1 in homozygous hereditary elliptocytosis. Implications for erythrocyte membrane stability.

1981 • 210 citations

Molecular cloning of protein 4.1, a major structural element of the human erythrocyte membrane skeleton.

1986 • 205 citations

Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin.

1991 • 203 citations

Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.

1991 • 198 citations

Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathway

1990 • 193 citations

Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin.

1992 • 189 citations

A structural model of human erythrocyte protein 4.1.

1984 • 183 citations

The secretion-stimulated 80K phosphoprotein of parietal cells is ezrin, and has properties of a membrane cytoskeletal linker in the induced apical microvilli.

1991 • 182 citations

Precise localization of human beta-globin gene complex on chromosome 11.

1979 • 175 citations

Radixin is a novel member of the band 4.1 family.

1991 • 167 citations

Neurofibromatosis 2: Clinical and DNA Linkage Studies of a Large Kindred

1988 • 162 citations

Identification of the functional site of erythrocyte protein 4.1 involved in spectrin-actin associations.

1986 • 147 citations

Radixin, a barbed end-capping actin-modulating protein, is concentrated at the cleavage furrow during cytokinesis [published erratum appears in J Cell Biol 1991 Sep;114(5):1101-3]

1991 • 147 citations

The Association of Posterior Capsular Lens Opacities With Bilateral Acoustic Neuromas in Patients With Neurofibromatosis Type 2

1989 • 121 citations

Cytovillin, a Microvillar Mr 75,000 Protein

1989 • 92 citations

Flanking markers bracket the neurofibromatosis type 2 (NF2) gene on chromosome 22.

1990 • 90 citations

Cloning and characterisation of an immunodominant major surface antigen of Echinococcus multilocularis

1991 • 82 citations

Physical maps of 4p16.3, the area expected to contain the Huntington disease mutation

1990 • 82 citations

Analysis of chromosome 22 deletions in neurofibromatosis type 2-related tumors.

1992 • 76 citations

Neurofibromatosis type 2 appears to be a genetically homogeneous disease.

1992 • 55 citations

Cytoskeleton-associated proteins: their role as cellular integrators in the neoplastic process

1985 • 50 citations

Molecular characterization of chromosome 22 deletions in schwannomas

1992 • 49 citations

The genomic structure of the human skeletal muscle sodium channel gene

1992 • 48 citations

Assessment of chromosome 22 anomalies in neurinomas by combined karyotype and RFLP analyses

1990 • 48 citations

Association of ezrin isoforms with the neuronal cytoskeleton

1991 • 44 citations

Loss of the Y chromosome in meningiomas

1990 • 33 citations

Immunofluorescent and immunochemical evidence for the expression of cytovillin in the microvilli of a wide range of cultured human cells

1988 • 32 citations

New markers for the neurofibromatosis-2 region generated by microdissection of chromosome 22

1991 • 32 citations

Moesin, a new cytoskeletal protein and constituent of filopodia: Its role in cellular functions

1992 • 30 citations

Serial transfer of a human gene to rodent cells by sequential chromosome-mediated gene transfer.

1977 • 28 citations

Loss of chromosome 22 alleles in human sporadic spinal schwannomas

1991 • 22 citations

A radiation hybrid map of the region on human chromosome 22 containing the neurofibromatosis type 2 locus

1992 • 22 citations

Parental origin of chromosome 22 loss in sporadic and NF2 neuromas

1991 • 21 citations

[Structure and function of human erythrocyte cytoskeletal protein 4.1].

1987 • 7 citations

The genetic disorders of the red cell skeleton.

1991 • 4 citations

Dinucleotide repeat polymorphism at the topoisomerase (DNA) I pseudogene 2 (TOPIP2)

1992 • 3 citations