Expression of isoforms and splice variants of the latent transforming growth factor β binding protein (LTBP) in cultured human liver myofibroblasts

Transforming Growth Factor β in Tissue Fibrosis

1994 • 3,055 citations

The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies

1993 • 1,444 citations

A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1.

1991 • 509 citations

A freeze-squeeze method for recovering long DNA from agarose gels

1975 • 478 citations

Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein

1994 • 450 citations

TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences

1990 • 447 citations

Human Mast Cell Chymase and Leukocyte Elastase Release Latent Transforming Growth Factor-β1 from the Extracellular Matrix of Cultured Human Epithelial and Endothelial Cells

1995 • 398 citations

TGF-β receptors and actions

1994 • 291 citations

Dual role for the latent transforming growth factor-beta binding protein in storage of latent TGF-beta in the extracellular matrix and as a structural matrix protein.

1995 • 273 citations

Molecular Mechanisms of Liver Fibrogenesis – A Homage to the Role of Activated Fat-Storing Cells

1995 • 237 citations

Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1.

1996 • 236 citations

Latent transforming growth factor-beta 1 and its binding protein are components of extracellular matrix microfibrils.

1996 • 222 citations

Extracellular Matrix-Associated Transforming Growth Factor-β: Role in Cancer Cell Growth and Invasion

1998 • 209 citations

Release of transforming growth factor-beta 1 from the pericellular matrix of cultured fibroblasts and fibrosarcoma cells by plasmin and thrombin.

1992 • 204 citations

Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.

1994 • 192 citations

Transforming growth factor-beta 1, -beta 2, and -beta 3 secreted by a human glioblastoma cell line. Identification of small and different forms of large latent complexes.

1992 • 181 citations

Receptors for Transforming Growth Factor-β

1993 • 181 citations

Novel insights into the biology and physiology of the Ito cell

1995 • 181 citations

Isolation of a Novel Latent Transforming Growth Factor-β Binding Protein Gene (LTBP-3)

1995 • 147 citations

Identification and Characterization of a New Latent Transforming Growth Factor-β-binding Protein, LTBP-4

1998 • 128 citations

Mitogenic effect of transforming growth factor-beta 1 on human Ito cells in culture: evidence for mediation by endogenous platelet-derived growth factor.

1993 • 127 citations

Immunological measurement of transforming growth factor-beta 1 (TGF-beta1) in blood; assay development and comparison.

1997 • 124 citations

Cellular and extracellular biology of the latent transforming growth factor-β binding proteins

1998 • 104 citations

Mitogenic effect of transforming growth factor-β1 on human ito cells in culture: Evidence for mediation by endogenous platelet-derived growth factor

1993 • 94 citations

Transforming growth factor-beta (TGF-beta): a key-role in liver fibrogenesis.

1995 • 94 citations

Immunological measurement of transforming growth factor-beta 1 (TGF-β1) in blood; assay development and comparison

1997 • 91 citations

Efficient Association of an Amino-terminally Extended Form of Human Latent Transforming Growth Factor-β Binding Protein with the Extracellular Matrix

1995 • 89 citations

The Cutaneous Microfibrillar Apparatus Contains Latent Transforming Growth Factor-β Binding Protein-1 (LTBP-1) and is a Repository for Latent TGF-β1

1998 • 83 citations

Sequence and expression of a novel member (LTBP‐4) of the family of latent transforming growth factor‐β binding proteins

1997 • 81 citations

Perisinusoidal lipocytes and fibrogenesis.

1994 • 74 citations

Human myofibroblastlike cells obtained by outgrowth are representative of the fibrogenic cells in the liver

1995 • 55 citations

Structural and Sequence Analysis of TGF-β2 cDNA Clones Predicts Two Different Precursor Proteins Produced by Alternative mRNA Splicing

1988 • 53 citations

Isoforms and splice variant of transforming growth factor β–binding protein in rat hepatic stellate cells

1998 • 52 citations

Molecular and functional aspects of latent transforming growth factor-β binding protein: just a masking protein?

1999 • 48 citations

Cultured Ito cells of rat liver express the α₂‐macroglobulin gene

1987 • 45 citations

Analysis of the expression pattern of the latent transforming growth factor ? binding protein isoforms in normal and diseased human liver reveals a new splice variant missing the proteinase-sensitive hinge region

1998 • 42 citations

Loss of a consensus heparin binding site by alternative splicing of latent transforming growth factor‐β binding protein‐1

1998 • 35 citations

Expression of alternatively spliced human latent transforming growth factor β binding protein‐1

1998 • 26 citations

Expression and release of the latent transforming growth factor ? binding protein by hepatocytes from rat liver

1997 • 26 citations

Immunolocalization of latent transforming growth factor-� binding protein-1 (LTBP1) during mouse development: possible roles in epithelial and mesenchymal cytodifferentiation

1999 • 24 citations