Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1.

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils.

1986 • 1,129 citations

Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium.

1988 • 962 citations

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes

1991 • 666 citations

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.

1988 • 648 citations

Latent transforming growth factor-beta from human platelets. A high molecular weight complex containing precursor sequences.

1988 • 548 citations

The TGF-β family and its composite receptors

1994 • 539 citations

A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1.

1991 • 509 citations

Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein

1994 • 450 citations

TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences

1990 • 447 citations

Crystal Structure of Transforming Growth Factor-β2: an Unusual Fold for the Superfamily

1992 • 446 citations

Human Mast Cell Chymase and Leukocyte Elastase Release Latent Transforming Growth Factor-β1 from the Extracellular Matrix of Cultured Human Epithelial and Endothelial Cells

1995 • 398 citations

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices

1994 • 386 citations

Conversion of a high molecular weight latent β-TGF from chicken embryo fibroblasts into a low molecular weight active β-TGF under acidic conditions

1985 • 366 citations

Physicochemical Activation of Recombinant Latent Transforming Growth Factor-beta's 1, 2, and 3

1990 • 343 citations

An unusual feature revealed by the crystal structure at 2.2 Å resolution of human transforming growth fact or-β2

1992 • 337 citations

Transforming growth factor β: a matter of life and death

1994 • 306 citations

Structure and function of epidermal growth factor‐like regions in proteins

1988 • 305 citations

Isolation of the pericellular matrix of human fibroblast cultures.

1979 • 302 citations

Role for carbohydrate structures inTGF-β1 latency

1989 • 270 citations

Role of the latent TGF-beta binding protein in the activation of latent TGF-beta by co-cultures of endothelial and smooth muscle cells.

1993 • 241 citations

Type 1 Transforming Growth Factor Beta: Amplified Expression and Secretion of Mature and Precursor Polypeptides in Chinese Hamster Ovary Cells

1987 • 224 citations

Site-directed Mutagenesis of Cysteine Residues in the Pro Region of the Transforming Growth Factor β1 Precursor

1989 • 220 citations

Release of transforming growth factor-beta 1 from the pericellular matrix of cultured fibroblasts and fibrosarcoma cells by plasmin and thrombin.

1992 • 204 citations

The many faces of epidermal growth factor repeats.

1990 • 197 citations

Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.

1994 • 192 citations

Transforming growth factor-beta 1, -beta 2, and -beta 3 secreted by a human glioblastoma cell line. Identification of small and different forms of large latent complexes.

1992 • 181 citations

Characterization and autoregulation of latent transforming growth factor beta (TGF beta) complexes in osteoblast-like cell lines. Production of a latent complex lacking the latent TGF beta-binding protein.

1994 • 173 citations

Molecular cloning of the large subunit of transforming growth factor type beta masking protein and expression of the mRNA in various rat tissues.

1990 • 162 citations

Construction of a Novel Oncogene Based on Synthetic Sequences Encoding Epidermal Growth Factor

1987 • 162 citations

Isolation of a Novel Latent Transforming Growth Factor-β Binding Protein Gene (LTBP-3)

1995 • 147 citations

Macrophage and foam cell release of matrix-bound growth factors. Role of plasminogen activation

1993 • 137 citations

Activation of Latent Transforming Growth Factor ß

1993 • 118 citations

The mechanism for the activation of latent TGF-beta during co-culture of endothelial cells and smooth muscle cells: cell-type specific targeting of latent TGF-beta to smooth muscle cells.

1993 • 114 citations

Thrombin-induced release of active basic fibroblast growth factor- heparan sulfate complexes from subendothelial extracellular matrix

1993 • 95 citations

Retention of the transforming growth factor-beta 1 precursor in the Golgi complex in a latent endoglycosidase H-sensitive form.

1992 • 92 citations

The many faces of epidermal growth factor repeats.

1990 • 68 citations

Lack of the latent transforming growth factor beta binding protein in malignant, but not benign prostatic tissue.

1993 • 61 citations

Transforming growth factors-beta as regulators of cellular growth and phenotype.

1992 • 51 citations

Mapping of human and murine genes for latent TGF-? binding protein-2 (LTBP2)

1995 • 25 citations