Mitogenic effect of transforming growth factor-β1 on human ito cells in culture: Evidence for mediation by endogenous platelet-derived growth factor

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

1990 • 756 citations

Transforming Growth Factors β1 and α in Chronic Liver Disease

1991 • 655 citations

Cells of the hepatic sinusoid

1989 • 589 citations

Cells of the hepatic sinusoid

1998 • 557 citations

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

1986 • 541 citations

Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells.

1989 • 481 citations

Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo.

1990 • 432 citations

cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.

1989 • 413 citations

Immunocytochemical Detection of Desmin in Fat-Storing Cells (Ito Cells)

1984 • 393 citations

Cellular distribution of transforming growth factor-beta 1 and procollagen types I, III, and IV transcripts in carbon tetrachloride-induced rat liver fibrosis.

1990 • 354 citations

Maintenance of Differentiated Phenotype of Cultured Rat Hepatic Lipocytes by Basement Membrane Matrix

1989 • 353 citations

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.

1988 • 338 citations

Isolated hepatic lipocytes and kupffer cells from normal human liver: Morphological and functional characteristics in primary culture

1992 • 288 citations

In situ hybridization for procollagen types I, III and IV mRNA in normal and fibrotic rat liver: Evidence for predominant expression in nonparenchymal liver cells

1989 • 281 citations

Alcoholic liver injury in baboons: Transformation of lipocytes to transitional cells

1984 • 275 citations

Cellular Sources of Noncollagenous Matrix Proteins: Role of Fat-Storing Cells in Fibrogenesis

1990 • 227 citations

Role of PDGF-A expression in the control of vascular smooth muscle cell growth by transforming growth factor-beta.

1990 • 214 citations

Cellular Sources of Collagen and Regulation of Collagen Production in Liver

1990 • 197 citations

Procollagen expression by nonparenchymal rat liver cells in experimental biliary fibrosis

1990 • 192 citations

Lipocytes and transitional cells in alcoholic liver disease: A morphometric study

1988 • 187 citations

Differential effects of interleukin‐1α, tumor necrosis factor α, and transforming growth factor β1 on cell proliferation and collagen formation by cultured fat‐storing cells

1989 • 178 citations

In vitro differentiation of fat-storing cells parallels marked increase of collagen synthesis and secretion

1989 • 175 citations

Collagen measured in primary cultures of normal rat hepatocytes derives from lipocytes within the monolayer.

1988 • 157 citations

TGF‐β stimulates primary human skin fibroblast DNA synthesis via an autocrine production of PDGF‐related peptides

1989 • 154 citations

Regulation of TGFβ gene expression in rat liver intoxicated with carbon tetrachloride

1990 • 137 citations

Appearance of α‐smooth‐muscle‐actin‐positive cells in hepatic fibrosis

1991 • 127 citations

Transforming growth factor β responsiveness is modulated by the extracellular collagen matrix during hepatic ito cell culture

1988 • 125 citations

Structure and sequence of the human c-sis/platelet-derived growth factor 2 (SIS/PDGF2) transcriptional unit.

1986 • 117 citations

Early alcoholic liver injury

1986 • 115 citations

Mechanism of γ-glutamyl transpeptidase release in serum during intrahepatic and extrahepatic cholestasis in the rat: A histochemical, biochemical and molecular approach

1990 • 113 citations

Mitogenic signals for platelet-derived growth factor isoforms in liver fat-storing cells

1991 • 112 citations

Immunohistochemical detection of transforming growth factor-β1 in fibrotic liver diseases

1991 • 111 citations

Modulation of hepatic lipocyte proteoglycan synthesis and proliferation by Kupffer cell-derived transforming growth factors type β1 and type α

1990 • 103 citations

Desmin distinguishes cultured fat-storing cells from myofibroblasts, smooth muscle cells and fibroblasts in the rat

1988 • 80 citations

Liver fat storing cell proliferation is stimulated by epidermal growth factor/transforming growth factor alpha and inhibited by transforming growth factor beta

1989 • 76 citations

Phenotypic modulation in lipocytes in experimental liver fibrosis

1991 • 74 citations

Inhibition of normal rat kidney cell growth by transforming growth factor-β is mediated by collagen

1989 • 68 citations

Retinoic acid and transforming growth factor β differentially inhibit platelet-derived-growth-factor-induced Ito-cell activation

1991 • 60 citations

Differential expression of platelet-derived growth factor α- and β-receptors on fat-storing cells and endothelial cells of rat liver

1991 • 59 citations

Transforming Growth Factor-β Induces Platelet-Derived Growth Factor (PDGF) Messenger RNA and PDGF Secretion while Inhibiting Growth in Normal Human Mammary Epithelial Cells

1990 • 50 citations

Modulation of extracellular matrix components during dimethylnitrosamine-induced cirrhosis

1990 • 44 citations

Minor contribution of hepatocytes to collagen production in normal and early fibrotic rat livers

1991 • 36 citations

Isolation, culture and main characteristics of mouse fat-storing cells: Interaction with viruses

1989 • 32 citations

Effect of fasting on organic anion uptake by isolated rat liver cells

1981 • 31 citations