Angiotensin Induces Inflammatory Activation of Human Vascular Smooth Muscle Cells

Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure

1991 • 8,296 citations

Effect of Captopril on Mortality and Morbidity in Patients with Left Ventricular Dysfunction after Myocardial Infarction

1992 • 5,885 citations

Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men

1997 • 5,442 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

Effect of Enalapril on Mortality and the Development of Heart Failure in Asymptomatic Patients with Reduced Left Ventricular Ejection Fractions

1992 • 3,708 citations

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

1994 • 2,753 citations

Molecular Bases of the Acute Coronary Syndromes

1995 • 2,049 citations

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

1992 • 1,956 citations

Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology.

1994 • 1,913 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.

1990 • 1,377 citations

Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells.

1990 • 1,147 citations

Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells.

1988 • 1,077 citations

A Prospective Evaluation of an Angiotensin-Converting–Enzyme Gene Polymorphism and the Risk of Ischemic Heart Disease

1995 • 920 citations

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

1996 • 795 citations

Elevated Levels of Interleukin-6 in Unstable Angina

1996 • 744 citations

Detection of activated T lymphocytes in the human atherosclerotic plaque.

1989 • 739 citations

Association of the Renin-Sodium Profile with the Risk of Myocardial Infarction in Patients with Hypertension

1991 • 734 citations

The Pathogenesis of Atherosclerosis: Atherogenesis and Inflammation

1989 • 701 citations

Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II.

1992 • 648 citations

Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells.

1989 • 632 citations

Endothelial nuclear factor-kappa B and the initiation of the atherosclerotic lesion.

1993 • 525 citations

Angiotensin-Converting Enzyme Inhibition Prevents Arterial Nuclear Factor-κB Activation, Monocyte Chemoattractant Protein-1 Expression, and Macrophage Infiltration in a Rabbit Model of Early Accelerated Atherosclerosis

1997 • 502 citations

Interleukin 6: A Multifunctional Cytokine Regulating Immune Reactions and the Acute Phase Protein Response

1990 • 483 citations

Multiple autocrine growth factors modulate vascular smooth muscle cell growth response to angiotensin II.

1993 • 470 citations

Increased Accumulation of Tissue ACE in Human Atherosclerotic Coronary Artery Disease

1996 • 431 citations

Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit.

1990 • 419 citations

Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis.

1992 • 381 citations

Cytokines Regulate Vascular Functions Related to Stability of the Atherosclerotic Plaque

1995 • 374 citations

Proliferating or interleukin 1-activated human vascular smooth muscle cells secrete copious interleukin 6.

1990 • 364 citations

Effects of captopril on ischemic events after myocardial infarction. Results of the Survival and Ventricular Enlargement trial. SAVE Investigators.

1994 • 337 citations

Human vascular smooth muscle cells. Target for and source of tumor necrosis factor.

1989 • 333 citations

Stimulation of Collagen and Glycosaminoglycan Production in Cultured Human Adult Dermal Fibroblasts by Recombinant Human Interleukin 6

1991 • 315 citations

Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease

1995 • 310 citations

Effects of angiotensin II and vasopressin on human smooth muscle cells in vitro

1981 • 306 citations

Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells

1991 • 288 citations

Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1, and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobulin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase.

1993 • 275 citations

The Nuclear Factor κ-B Signaling Pathway Participates in Dysregulation of Vascular Smooth Muscle Cells in Vitroand in Human Atherosclerosis

1997 • 265 citations

Angiotensin II induces plasminogen activator inhibitor-1 and -2 expression in vascular endothelial and smooth muscle cells.

1995 • 262 citations

HHF35, a muscle actin-specific monoclonal antibody. II. Reactivity in normal, reactive, and neoplastic human tissues.

1987 • 258 citations

Functional and Biochemical Analysis of Angiotensin II–Forming Pathways in the Human Heart

1997 • 246 citations

Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells

1991 • 230 citations

Human interleukin 1 induces interleukin 1 gene expression in human vascular smooth muscle cells.

1987 • 223 citations

Culture of quiescent arterial smooth muscle cells in a defined serum‐free medium

1983 • 220 citations

Activation of human peripheral monocytes by angiotensin II

1994 • 210 citations

Plasma Renin Activity: A Risk Factor for Myocardial Infarction in Hypertensive Patients

1997 • 197 citations

Expression of monocyte chemotactic protein and interleukin-8 by cytokine-activated human vascular smooth muscle cells.

1991 • 191 citations

Cytokines and growth factors in atherogenesis.

1992 • 183 citations

Nitric Oxide Attenuates Vascular Smooth Muscle Cell Activation by Interferon-γ

1996 • 145 citations

Thrombin Potently Stimulates Cytokine Production in Human Vascular Smooth Muscle Cells but Not in Mononuclear Phagocytes

1996 • 119 citations

Plasma Renin Activity and Ischemic Heart Disease

1993 • 111 citations

Angiotensin II stimulates interleukin-6 release from cultured mouse mesangial cells.

1995 • 100 citations

Angiotensin II Stimulation of Vascular Smooth Muscle Cells: Secondary Signalling Mechanisms

1989 • 46 citations

Role of Endothelial Kinins in Control of Coronary Nitric Oxide Production

1997 • 44 citations

Introduction to a structural basis for renal and vascular complications in diabetes and hypertension

1992 • 17 citations