Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger rna in response to kainate-induced excitation

Excitotoxic cell death

1992 • 2,307 citations

Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy

1985 • 1,730 citations

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors.

1990 • 899 citations

BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF

1991 • 699 citations

Limbic Seizures Increase Neuronal Production of Messenger RNA for Nerve Growth Factor

1989 • 624 citations

Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs

1992 • 564 citations

Kainic acid induced seizures: Neurochemical and histopathological changes

1983 • 526 citations

Excitatory amino acid receptors in epilepsy

1990 • 428 citations

Glial Cell Line-Derived Neurotrophic Factor Is Expressed in the Developing but Not Adult Striatum and Stimulates Developing Dopamine Neurons in Vivo

1993 • 384 citations

Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus

1990 • 332 citations

Hippocampal damage and kainic acid injection induce a rapid increase in mRNA for BDNF and NGF in the rat brain

1991 • 295 citations

Kainic acid-induced seizures stimulate increased expression of nerve growth factor mRNA in rat hippocampus

1991 • 280 citations

IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage

1992 • 253 citations

Regionally specific and rapid increases in brain-derived neurotrophic factor messenger RNA in the adult rat brain following seizures induced by systemic administration of kainic acid

1992 • 174 citations

TGF-β1 mRNA Increases in Macrophage/Microglial Cells of the Hippocampus in Response to Deafferentation and Kainic Acid-Induced Neurodegeneration

1993 • 174 citations

Limbic seizures induce a differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3, in the rat hippocampus

1992 • 148 citations

Basic fibroblast growth factor mRNA increases in specific brain regions following convulsive seizures

1992 • 97 citations

Regulation of brain neurctrophin expression by physiological activity

1992 • 77 citations

Fast and widespread increase of basic fibroblast growth factor messenger RNA and protein in the forebrain after kainate-induced seizures

1993 • 65 citations

MK801 pretreatment reduces kainic acid-induced spontaneous seizures in prepubescent rats

1993 • 28 citations