The Use of Lymphocyte Function–Associated Antigen (Lfa)-1–Deficient Mice to Determine the Role of Lfa-1, Mac-1, and α4 Integrin in the Inflammatory Response of Neutrophils

Adhesion molecules and inflammatory injury

1994 • 1,023 citations

α4 integrins mediate lymphocyte attachment and rolling under physiologic flow

1995 • 1,018 citations

A Novel Role for the β2 Integrin CD11b/CD18 in Neutrophil Apoptosis: A Homeostatic Mechanism in Inflammation

1996 • 645 citations

Hematopoietic Progenitor Cell Rolling in Bone Marrow Microvessels: Parallel Contributions by Endothelial Selectins and Vascular Cell Adhesion Molecule 1

1998 • 453 citations

Relative Contribution of LFA-1 and Mac-1 to Neutrophil Adhesion and Migration

1999 • 403 citations

Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo.

1987 • 370 citations

Lymphocyte Migration in Lymphocyte Function-associated Antigen (LFA)-1–deficient Mice

1999 • 329 citations

Subsecond Induction of α4 Integrin Clustering by Immobilized Chemokines Stimulates Leukocyte Tethering and Rolling on Endothelial Vascular Cell Adhesion Molecule 1 under Flow Conditions

2000 • 327 citations

Leukocyte interactions with vascular endothelium. New insights into selectin-mediated attachment and rolling.

1995 • 295 citations

LFA-1 is sufficient in mediating neutrophil emigration in Mac-1-deficient mice.

1997 • 291 citations

LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor.

1996 • 277 citations

Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice

1997 • 275 citations

L-selectin function is required for beta 2-integrin-mediated neutrophil adhesion at physiological shear rates in vivo

1992 • 239 citations

L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo.

1994 • 199 citations

Differential surface expression of cell adhesion molecules during granulocyte maturation

1993 • 188 citations

Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: Effect of lipocortin 1

1998 • 177 citations

Leukocyte Arrest During Cytokine-Dependent Inflammation In Vivo

2000 • 170 citations

Functional α4-integrin: A newly identified pathway of neutrophil recruitment in critically ill septic patients

2001 • 142 citations

Sequential binding of CD11a/CD18 and CD11b/CD18 defines neutrophil capture and stable adhesion to intercellular adhesion molecule–1

2000 • 132 citations

The LFA-1 Integrin Supports Rolling Adhesions on ICAM-1 Under Physiological Shear Flow in a Permissive Cellular Environment

2000 • 131 citations

Optimal selectin-mediated rolling of leukocytes during inflammationin vivorequires intercellular adhesion molecule-1 expression

1998 • 127 citations

Transendothelial migration and trafficking of leukocytes in LFA-1-deficient mice

1998 • 125 citations

Neutrophils Can Adhere Via α4β1 -Integrin Under Flow Conditions

1997 • 112 citations

Neutrophils Can Adhere Via α4β1 -Integrin Under Flow Conditions

1997 • 105 citations

The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat.

1992 • 98 citations

The α4-integrin: an alternative pathway for neutrophil recruitment?

1999 • 81 citations

Hydrodynamic Shear Shows Distinct Roles for LFA-1 and Mac-1 in Neutrophil Adhesion to Intercellular Adhesion Molecule-1

1998 • 72 citations

The Lymphocyte Function–associated Antigen 1 I Domain Is a Transient Binding Module for Intercellular Adhesion Molecule (ICAM)-1 and ICAM-3 in Hydrodynamic Flow

1997 • 71 citations

Mac‐1 (CD11b/CD18) is the predominant β₂ (CD18) integrin mediating human neutrophil migration through synovial and dermal fibroblast barriers

1996 • 40 citations

The in vivo and in vitro effects of antibodies against rabbit beta 2-integrins.

1994 • 26 citations