LFA-1 is sufficient in mediating neutrophil emigration in Mac-1-deficient mice.

Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro.

1989 • 1,115 citations

Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mo1, anti-CD11b) that inhibits leukocyte adhesion.

1988 • 650 citations

Recognition of an endothelial determinant for CD 18-dependent human neutrophil adherence and transendothelial migration.

1988 • 626 citations

Structure and Function of Leukocyte Integrins

1990 • 620 citations

Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11/CD18 integrins.

1989 • 577 citations

Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1.

1993 • 563 citations

Cloning of the $beta; subunit of the leukocyte adhesion proteins: Homology to an extracellular matrix receptor defines a novel supergene family

1987 • 520 citations

Fibrin(ogen) mediates acute inflammatory responses to biomaterials.

1993 • 446 citations

Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: structure-function assessments employing subunit-specific monoclonal antibodies.

1986 • 423 citations

Mac-1 (CD11b/CD18) mediates adherence-dependent hydrogen peroxide production by human and canine neutrophils.

1990 • 421 citations

Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1.

1989 • 413 citations

Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo.

1987 • 370 citations

Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage.

1994 • 328 citations

Interleukin 1 and tumor necrosis factor stimulate human vascular endothelial cells to promote transendothelial neutrophil passage.

1989 • 327 citations

Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence.

1992 • 304 citations

Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily.

1989 • 285 citations

The human leukocyte adhesion glycoprotein Mac-1 (complement receptor type 3, CD11b) alpha subunit. Cloning, primary structure, and relation to the integrins, von Willebrand factor and factor B.

1988 • 281 citations

LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor.

1996 • 277 citations

CD11c/CD18 on neutrophils recognizes a domain at the N terminus of the A alpha chain of fibrinogen.

1991 • 275 citations

Abnormalities of polymorphonuclear leukocyte function associated with a heritable deficiency of high molecular weight surface glycoproteins (GP138): common relationship to diminished cell adherence.

1984 • 273 citations

Motility and Adhesiveness in Human Neutrophils

1979 • 264 citations

A novel leukointegrin, αdβ2, binds preferentially to ICAM-3

1995 • 255 citations

Gene targeting yields a CD18-mutant mouse for study of inflammation.

1993 • 240 citations

Neutrophil-induced liver cell injury in endotoxin shock is a CD11b/CD18-dependent mechanism

1991 • 237 citations

Anti‐CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat

1994 • 231 citations

Genomic DNA microextraction: A method to screen numerous samples

1992 • 221 citations

Neutrophil migration across monolayers of cytokine-prestimulated endothelial cells: a role for platelet-activating factor and IL-8.

1992 • 213 citations

Monoclonal antibodies to leukocyte integrins CD11a/CD18 and CD11b/CD18 or intercellular adhesion molecule-1 inhibit chemoattractant-stimulated neutrophil transendothelial migration in vitro

1991 • 210 citations

Molecular determinants of acute inflammatory responses to biomaterials.

1996 • 206 citations

Recruitment of CD11b/CD18 to the neutrophil surface and adherence-dependent cell locomotion.

1992 • 193 citations

Amino acid sequence of the murine Mac-1 alpha chain reveals homology with the integrin family and an additional domain related to von Willebrand factor.

1988 • 160 citations

Monoclonal Antibodies to the Leukocyte Membrane CD18 Glycoprotein Complex and to Intercellular Adhesion Molecule-1 Inhibit Leukocyte-Endothelial Adhesion in Rabbits

1991 • 153 citations

Functional interaction between the integrin antagonist neutrophil inhibitory factor and the I domain of CD11b/CD18

1994 • 128 citations

Experimental chronic renal ischemia: Morphologic and immunologic studies

1992 • 106 citations

The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat.

1992 • 98 citations

Role of Mac-1 and ICAM-1 in ischemia-reperfusion injury in a microcirculation model of BALB/C mice

1994 • 91 citations

Subcellular distribution and mobilization of MAC-1 (CD11b/CD18) in neonatal neutrophils

1990 • 84 citations

Lysosomal elastase and cathepsin G in beige mice. Neutrophils of beige (Chediak-Higashi) mice selectively lack lysosomal elastase and cathepsin G.

1986 • 65 citations

Molecular determinants of lipid mediator-induced leukocyte adherence and emigration in rat mesenteric venules

1994 • 65 citations

Co-stimulation of T cell proliferation by transforming growth factor-beta 1.

1991 • 62 citations

Recurrent Infection in Glycogenosis Type Ib: Abnormal Neutrophil Motility Related to Impaired Redistribution of Adhesion Sites

1981 • 60 citations

The Role of Protected Extracellular Compartments in Interactions between Leukocytes, and Platelets, and Fibrin/Fibrinogen Matricesa

1992 • 50 citations

Efficacy of antibodies to adhesion molecules, CDlla or CD18, in rabbit models of uveitis

1993 • 33 citations

The in vivo and in vitro effects of antibodies against rabbit beta 2-integrins.

1994 • 26 citations

Contribution of LFA-1 and Mac-1 to CD18-dependent neutrophil emigration in a neonatal rabbit model

1996 • 23 citations

The role of CD11/CD18 integrins in the reverse passive Arthus reaction in rat dermal tissue

1996 • 13 citations

Comparative studies of microscopically determined aggregation, degranulation, and light transmission after chemotactic activation of adult and newborn neutrophils

1990 • 12 citations

Subcellular distribution and mobilization of MAC-1 (CD11b/CD18) in neonatal neutrophils

1990 • 6 citations

Comparative studies of microscopically determined aggregation, degranulation, and light transmission after chemotactic activation of adult and newborn neutrophils

1990 • 3 citations

Adhesion Molecules in the Shwartzman Response

1993 • 1 citations

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