LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor.

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

1991 • 2,806 citations

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

1984 • 1,518 citations

The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System

1987 • 1,104 citations

Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.

1982 • 740 citations

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

1990 • 689 citations

The Severe and Moderate Phenotypes of Heritable Mac-1, LFA-1 Deficiency: Their Quantitative Definition and Relation to Leukocyte Dysfunction and Clinical Features

1985 • 644 citations

The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions.

1983 • 583 citations

Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1.

1993 • 563 citations

Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

1990 • 558 citations

The Virology and Immunobiology of Lymphocytic Choriomeningitis Virus Infection

1980 • 554 citations

CD8 is needed for development of cytotoxic T but not helper T cells

1991 • 528 citations

The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester.

1986 • 487 citations

Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells

1989 • 423 citations

A human lymphocyte‐associated antigen involved in cell‐mediated lympholysis

1983 • 315 citations

Fibroblasts as Efficient Antigen-Presenting Cells in Lymphoid Organs

1995 • 308 citations

CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide.

1995 • 303 citations

Evidence for an accessory role of LFA-1 in lymphocyte-high endothelium interaction during homing.

1988 • 302 citations

Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA-1): mechanism of blockade of T lymphocyte-mediated killing and effects on other T and B lymphocyte functions.

1981 • 292 citations

Lymphocyte function-associated antigen 1 (LFA-1): a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte-mediated killing.

1981 • 287 citations

Inhibition of murine T cell‐mediated cytolysis and T cell proliferation by a rat monoclonal antibody immunoprecipitating two lymphoid cell surface polypeptides of 94000 and 180000 molecular weight

1982 • 237 citations

Regulatory properties of LFA-1 α and β chains in human T-lymphocyte activation

1988 • 225 citations

Deficiency of a leukocyte surface glycoprotein (LFA-1) in two patients with Mo1 deficiency. Effects of cell activation on Mo1/LFA-1 surface expression in normal and deficient leukocytes.

1984 • 224 citations

LFA‐1 and Lyt‐2,3, Molecules Associated with T Lymphocyte‐Mediated Killing; and Mac‐1, an LFA‐1 Homologue Associated with Complement Receptor Function¹

1982 • 223 citations

Defective natural killer cytotoxicity and polymorphonuclear leukocyte antibody-dependent cellular cytotoxicity in patients with LFA-1/OKM-1 deficiency.

1984 • 146 citations

Identification of a Cell Surface Protein Complex Mediating Phorbol Ester‐Induced Adhesion (Binding) among Human Mononuclear Leukocytes

1985 • 139 citations

ABSENCE OF MONOCLONAL-ANTIBODY-DEFINED PROTEIN COMPLEX IN BOY WITH ABNORMAL LEUCOCYTE FUNCTION

1984 • 135 citations

Triggering of co-mitogenic signals in T cell proliferation by anti-LFA-1 (CD18, CD11a), LFA-3, and CD7 monoclonal antibodies.

1988 • 121 citations

Reduced contact sensitivity reactions in mice treated with monoclonal antibodies to leukocyte function-associated molecule-1 and intercellular adhesion molecule-1.

1993 • 120 citations

A novel canine leukointegrin, alpha d beta 2, is expressed by specific macrophage subpopulations in tissue and a minor CD8+ lymphocyte subpopulation in peripheral blood.

1995 • 103 citations

Subnormal serum concentrations of IgG2 in children with frequent infections associated with varied patterns of immunologic dysfunction

1990 • 87 citations

Intercellular adhesion molecule‐3 is the predominant co‐stimulatory ligand for leukocyte function antigen‐1 on human blood dendritic cells

1995 • 81 citations

Abnormal adherence-related functions of neutrophils, monocytes, and Epstein-Barr virus-transformed B cells in a patient with C3bi receptor deficiency

1985 • 59 citations

Lymphocytic Choriomeningitis Virus Infection is Associated with Long‐Standing Perturbation of LFA‐1 Expression on CD8⁺ T Cells

1995 • 58 citations

Monoclonal Antibodies That Block the Activity of Leukocyte Function-associated Antigen 1 Recognize Three Discrete Epitopes in the Inserted Domain of CD11a

1995 • 51 citations

Mouse thymic epithelial cell lines interact with and select a CD3^lowCD4⁺ CD8⁺ thymocyte subset through an LFA-1-dependent adhesion -de-adhesion mechanism

1990 • 34 citations

The Function of LFA-1 in Cell-Mediated Killing and Adhesion: Studies on Heritable LFA-1, Mac-1 Deficiency and on Lymphoid Cell Self-Aggregation

1985 • 24 citations

Analysis of the role of leukocyte function-associated antigen-1 in activation of human influenza virus-specific T cell clones.

1990 • 18 citations

Differences between Primed Allogeneic T‐Cell Responses and the Primary Mixed Leucocyte Reaction

1988 • 15 citations

The role of CD18 in phorbol ester-induced human monocyte-mediated cytotoxicity

1988 • 8 citations

Novel tumor-associated accessory molecules involved in the gamma/delta cytotoxic t-lymphocyte-Burkitt's lymphoma interaction

1995 • 5 citations

The in vivo role of leukocyte function-associated antigen-1 in cytotoxic cell activity against tumors induced by Moloney-murine sarcoma/leukemia retroviral complex.

1992 • 1 citations