Increased Expression of CYR61, an Extracellular Matrix Signaling Protein, in Human Benign Prostatic Hyperplasia and Its Regulation by Lysophosphatidic Acid

Integrin Signaling

1999 • 3,705 citations

Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins

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Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger

1995 • 592 citations

The Connective Tissue Growth Factor/Cysteine- Rich 61/Nephroblastoma Overexpressed (CCN) Family*

1999 • 567 citations

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1‐phosphate

1998 • 516 citations

The CCN family: a new stimulus package

2003 • 495 citations

CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

1998 • 487 citations

Cyr61, a Product of a Growth Factor-Inducible Immediate-Early Gene, Promotes Cell Proliferation, Migration, and Adhesion

1996 • 339 citations

Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.

2001 • 299 citations

Lysophosphatidic acid is a bioactive mediator in ovarian cancer

2002 • 271 citations

Lysophospholipid Growth Factors in the Initiation, Progression, Metastases, and Management of Ovarian Cancer

2000 • 243 citations

Identification of integrin αMβ2 as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions

2002 • 232 citations

Lysophospholipid receptor nomenclature

2002 • 225 citations

Molecular Cloning and Characterization of a Lysophosphatidic Acid Receptor, Edg-7, Expressed in Prostate

2000 • 206 citations

Dysregulated expression of growth factors and their receptors in the development of prostate cancer

2000 • 171 citations

Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator

1994 • 152 citations

Factor VIIa and Thrombin Induce the Expression of Cyr61 and Connective Tissue Growth Factor, Extracellular Matrix Signaling Proteins That Could Act as Possible Downstream Mediators in Factor VIIa·Tissue Factor-induced Signal Transduction

2000 • 149 citations

Breast Cancer

2001 • 146 citations

Symptomatic and asymptomatic benign prostatic hyperplasia: Molecular differentiation by using microarrays

2002 • 127 citations

The angiogenic factor CYR61 in breast cancer: molecular pathology and therapeutic perspectives.

2003 • 118 citations

Expression of CYR61, an Angiogenic Immediate Early Gene, in Arteriosclerosis and Its Regulation by Angiotensin II

2002 • 113 citations

Role for 18:1 Lysophosphatidic Acid as an Autocrine Mediator in Prostate Cancer Cells

2002 • 108 citations

Benign Prostatic Hyperplasia

1994 • 108 citations

Cyr61, a Member of the CCN Family, Is Required for MCF-7 Cell Proliferation: Regulation by 17β-Estradiol and Overexpression in Human Breast Cancer

2001 • 99 citations

Physiological responses to lysophosphatidic acid and related glycero-phospholipids

2001 • 93 citations

Mitogenic action of LPA in prostate

2002 • 83 citations

Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA‐binding proteins in activation of LPA receptors

2002 • 82 citations

Expression of the extracellular matrix signaling molecule Cyr61 is downregulated in prostate cancer

1998 • 81 citations

Aberrant Expression of Cyr61, a Member of the CCN (CTGF/Cyr61/Cef10/NOVH) Family, and Dysregulation by 17β-Estradiol and Basic Fibroblast Growth Factor in Human Uterine Leiomyomas

2001 • 75 citations

Human CYR61-mediated enhancement of bFGF-induced DNA synthesis in human umbilical vein endothelial cells

1998 • 73 citations

MITOGENIC SIGNALING IN ANDROGEN SENSITIVE AND INSENSITIVE PROSTATE CANCER CELL LINES

2000 • 71 citations

Lysophospholipid mediators of immunity and neoplasia

2002 • 65 citations

ESSENTIAL ROLE FOR G PROTEINS IN PROSTATE CANCER CELL GROWTH AND SIGNALING

2000 • 63 citations

Lysophosphatidic acid stimulates phospholipase D activity and cell proliferation in PC-3 human prostate cancer cells

1998 • 63 citations

Lysophosphatidic acid in airway function and disease

2002 • 55 citations

Report on the second international workshop on the CCN family of genes

2003 • 50 citations

Lysophosphatidic acid stimulates proliferation of cultured smooth muscle cells from human BPH tissue: Sildenafil and papaverin generate inhibition

2002 • 45 citations

Characterization of differential gene expression in monkey arterial neointima following balloon catheter injury.

2000 • 25 citations

Regulation of Expression of EDG Family Receptors in Human Prostate Cancer Cell Lines

2000 • 16 citations

Development of Quantitative Detection Assays for CYR61 as a New Marker for Benign Prostatic Hyperplasia

2003 • 14 citations

Conference summary on prostate growth and aging, 13–15 September 2000*

2001 • 7 citations

International Congress on Hormonal Steroids and Hormones and Cancer The angiogenic factor CYR61 in breast cancer: molecular pathology and therapeutic perspectives

2003 • 4 citations