Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu

Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors

1992 • 3,344 citations

de la Chapelle, A.

1997 • 3,184 citations

Multicolor Spectral Karyotyping of Human Chromosomes

1996 • 1,780 citations

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1988 • 1,160 citations

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

1994 • 982 citations

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1984 • 906 citations

Centrosome Amplification and a Defective G2–M Cell Cycle Checkpoint Induce Genetic Instability in BRCA1 Exon 11 Isoform–Deficient Cells

1999 • 814 citations

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation

1999 • 744 citations

ERBB2 oncogene in human breast cancer and its clinical significance

1998 • 457 citations

The Promise of Comparative Genomics in Mammals

2001 • 387 citations

Comparative genomic hybridization reveals a specific pattern of chromosomal gains and losses during the genesis of colorectal tumors

1996 • 377 citations

Molecular cytogenetics of primary breast cancer by CGH

1998 • 362 citations

THE CENTROSOME AND CELLULAR ORGANIZATION

1994 • 361 citations

Multicolour spectral karyotyping of mouse chromosomes

1996 • 313 citations

Genomic changes defining the genesis, progression, and malignancy potential in solid human tumors: A phenotype/genotype correlation

1999 • 282 citations

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

2000 • 281 citations

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

2000 • 274 citations

Comparative genomic hybridization of formalin-fixed, paraffin-embedded breast tumors reveals different patterns of chromosomal gains and losses in fibroadenomas and diploid and aneuploid carcinomas.

1995 • 230 citations

Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis

2000 • 220 citations

Specific Chromosomal Aberrations and Amplification of the AIB1 Nuclear Receptor Coactivator Gene in Pancreatic Carcinomas

1999 • 200 citations

Micronuclei: a biological indicator of radiation damage

1996 • 101 citations

p73 is transcriptionally regulated by DNA damage, p53, and p73

2001 • 92 citations

Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability

1998 • 90 citations

Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis.

1995 • 89 citations

ACUTE MYELOGENOUS LEUKAEMIA WITH C-MYC AMPLIFICATION AND DOUBLE MINUTE CHROMOSOMES

1985 • 87 citations

A recurring pattern of chromosomal aberrations in mammary gland tumors of MMTV-cmyc transgenic mice

1999 • 79 citations

Spectral karyotyping

1996 • 67 citations

A tumor suppressor gene on chromosome 1p32-pter controls the amplification of MYC family genes in breast cancer.

1994 • 48 citations

Rules and guidelines for nomenclature of mouse genes

1994 • 45 citations

Amplification of Ki-ras and elevation of MAP kinase activity during mammary tumor progression in C3(1)/SV40 Tag transgenic mice

1998 • 44 citations

The murine homolog of the human breast and ovarian cancer susceptibility geneBrca1 maps to mouse chromosome 11D

1996 • 13 citations