A recurring pattern of chromosomal aberrations in mammary gland tumors of MMTV-cmyc transgenic mice

Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors

1992 • 3,344 citations

Multicolor Spectral Karyotyping of Human Chromosomes

1996 • 1,780 citations

Atm-Deficient Mice: A Paradigm of Ataxia Telangiectasia

1996 • 1,467 citations

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1992 • 1,358 citations

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1984 • 906 citations

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization.

1994 • 748 citations

Genetic variants and strains of the Laboratory mouse

1996 • 500 citations

Consequences of widespread deregulation of the c-myc gene in transgenic mice: Multiple neoplasms and normal development

1986 • 427 citations

Molecular cytogenetics of primary breast cancer by CGH

1998 • 362 citations

Multicolour spectral karyotyping of mouse chromosomes

1996 • 313 citations

Quantitative analysis of comparative genomic hybridization

1995 • 304 citations

Comprehensive and definitive molecular cytogenetic characterization of HeLa cells by spectral karyotyping.

1999 • 300 citations

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.

1995 • 280 citations

Comparative genomic hybridization of formalin-fixed, paraffin-embedded breast tumors reveals different patterns of chromosomal gains and losses in fibroadenomas and diploid and aneuploid carcinomas.

1995 • 230 citations

Specific Chromosomal Aberrations and Amplification of the AIB1 Nuclear Receptor Coactivator Gene in Pancreatic Carcinomas

1999 • 200 citations

Genetic alterations in primary breast cancers and their metastases: Direct comparison using modified comparative genomic hybridization

1997 • 183 citations

Defining a role for c-Myc in breast tumorigenesis

1997 • 125 citations

Two distinct amplified regions at 17q11-q21 involved in human primary breast cancer.

1996 • 108 citations

Increased copy number at 17q22-q24 by CGH in breast cancer is due to high-level amplification of two separate regions

1997 • 97 citations

Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability

1998 • 90 citations

Synergistic interaction of transforming growth factor alpha and c-myc in mouse mammary and salivary gland tumorigenesis.

1995 • 89 citations

The MMTV/c-myc transgene and p53 null alleles collaborate to induce T-cell lymphomas, but not mammary carcinomas in transgenic mice.

1995 • 80 citations

Allelic loss on chromosome 1p is associated with progression and lymph node metastasis of primary breast carcinoma.

1998 • 70 citations

Allelic loss on chromosome 1p is Associated with progression and lymph node metastasis of primary breast carcinoma

1998 • 54 citations

Previously hidden chromosome aberrations in T(12;15)-positive BALB/c plasmacytomas uncovered by multicolor spectral karyotyping.

1997 • 48 citations

A tumor suppressor gene on chromosome 1p32-pter controls the amplification of MYC family genes in breast cancer.

1994 • 48 citations

DNA copy number changes associated with characteristic LOH in islet cell carcinomas of transgenic mice

1997 • 22 citations

c-Myc Dependent Initiation of Genomic Instability During Neoplastic Transformation

1997 • 14 citations