ACUTE MYELOGENOUS LEUKAEMIA WITH C-MYC AMPLIFICATION AND DOUBLE MINUTE CHROMOSOMES

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

1982 • 1,424 citations

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

1983 • 1,407 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia

1979 • 905 citations

Expression of Cellular Oncogenes in Human Malignancies

1984 • 840 citations

Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.

1983 • 764 citations

Evolution of tumours and the impact of molecular oncology

1985 • 666 citations

Gene amplification in cultured animal cells

1984 • 639 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line

1982 • 630 citations

Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas

1982 • 624 citations

Viral oncogenes

1985 • 605 citations

Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.

1982 • 570 citations

A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells

1983 • 485 citations

Metaphase Chromosome Anomaly: Association with Drug Resistance and Cell-Specific Products

1976 • 396 citations

Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia

1985 • 372 citations

Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion

1984 • 358 citations

Two human c-onc genes are located on the long arm of chromosome 8.

1982 • 329 citations

MINUTE CHROMATIN BODIES IN MALIGNANT TUMOURS OF CHILDHOOD

1965 • 286 citations

Transduction and rearrangement of the myc gene by feline leukaemia virus in naturally occurring T-cell leukaemias

1984 • 196 citations

Double minutes in human tumor cells

1982 • 194 citations

Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29.

1983 • 184 citations

Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma.

1984 • 182 citations

Unstable Methotrexate Resistance in Human Small-Cell Carcinoma Associated with Double Minute Chromosomes

1983 • 178 citations

Proviruses are adjacent to c-myc in some murine leukemia virus-induced lymphomas.

1984 • 177 citations

Amplification of the c- myb Oncogene in a Case of Human Acute Myelogenous Leukemia

1984 • 170 citations

Chromosomal sublocalization of human c-myb and c-fes cellular onc genes

1983 • 154 citations

Resistance to methotrexate due to gene amplification in a patient with acute leukemia.

1984 • 145 citations

Viral transduction of c-myc gene in naturally occurring feline leukaemias

1984 • 141 citations

Gene amplification in a leukemic patient treated with methotrexate.

1984 • 139 citations

Structure and Expression of the Oncogene c-myc in Fresh Tumor Material from Patients with Hematopoietic Malignancies

1984 • 128 citations

Isolation of a feline leukaemia provirus containing the oncogene myc from a feline lymphosarcoma

1984 • 109 citations

Chromosomal assignment of the human homologues of feline sarcoma virus and avian myeloblastosis virus onc genes.

1982 • 100 citations

Culture of bone marrow reveals more cells with chromosomal abnormalities than the direct method in patients with hematologic disorders

1981 • 93 citations

GENOMIC ALTERATIONS INVOLVING THE C-MYC PROTO-ONCOGENE LOCUS DURING THE EVOLUTION OF A CASE OF CHRONIC GRANULOCYTIC LEUKAEMIA

1984 • 91 citations

Structure and expression of the oncogene c-myc in fresh tumor material from patients with hematopoietic malignancies.

1984 • 89 citations

Oncogene expression in human leukemia

1984 • 87 citations

Chromosomes in acute nonlymphocytic leukemia

1986 • 77 citations

Double minutes in acute myeloid leukemia

1983 • 46 citations

Oncogenic intelligence: Oncogene activation by fusion of chromosomes in leukaemia

1985 • 36 citations

Mapping of amplified c-myb oncogene, sister chromatid exchanges, and karyotypic analysis of the COLO 205 colon carcinoma cell line

1985 • 17 citations