Involvement of distinct cellular compartments in the abnormal lymphoid organogenesis in lymphotoxin-alpha-deficient mice and alymphoplasia (aly) mice defined by the chimeric analysis.

Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm

1994 • 7,068 citations

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1999 • 3,340 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

‘Green mice’ as a source of ubiquitous green cells

1997 • 2,586 citations

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

1996 • 1,167 citations

A Putative Chemokine Receptor, BLR1, Directs B Cell Migration to Defined Lymphoid Organs and Specific Anatomic Compartments of the Spleen

1996 • 1,125 citations

Two TNF receptors

1992 • 1,048 citations

Requirement for NF-κB in osteoclast and B-cell development

1997 • 994 citations

The ikaros gene is required for the development of all lymphoid lineages

1994 • 976 citations

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1995 • 881 citations

Teratocarcinomas and embryonic stem cells : a practical approach

1987 • 878 citations

Development of peripheral lymphoid organs and natural killer cells depends on the helix–loop–helix inhibitor Id2

1999 • 841 citations

Characterization of tumor necrosis factor-deficient mice

1997 • 792 citations

LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator

1998 • 760 citations

The Lymphotoxin β Receptor Controls Organogenesis and Affinity Maturation in Peripheral Lymphoid Tissues

1998 • 710 citations

Developing Lymph Nodes Collect CD4 + CD3 − LTβ + Cells That Can Differentiate to APC, NK Cells, and Follicular Cells but Not T or B Cells

1997 • 654 citations

Distinct Roles in Lymphoid Organogenesis for Lymphotoxins α and β Revealed in Lymphotoxin β–Deficient Mice

1997 • 590 citations

Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface

1993 • 468 citations

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase

1999 • 448 citations

Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness.

1995 • 436 citations

Unraveling Function in the TNF Ligand and Receptor Families

1994 • 431 citations

Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs.

1996 • 392 citations

Role of Lymphotoxin and the Type I TNF Receptor in the Formation of Germinal Centers

1996 • 386 citations

Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice

1997 • 365 citations

A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice

1994 • 327 citations

Affinity maturation without germinal centres in lymphotoxin-α-deficient mice

1996 • 322 citations

Mature Follicular Dendritic Cell Networks Depend on Expression of Lymphotoxin β Receptor by Radioresistant Stromal Cells and of Lymphotoxin β and Tumor Necrosis Factor by B Cells

1999 • 314 citations

B Lymphocytes Induce the Formation of Follicular Dendritic Cell Clusters in a Lymphotoxin α–dependent Fashion

1998 • 296 citations

Lymph Node Genesis Is Induced by Signaling through the Lymphotoxin β Receptor

1998 • 294 citations

The Ligands and Receptors of the Lymphotoxin System

1995 • 262 citations

Hox11 controls the genesis of the spleen

1994 • 261 citations

A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+ CD3- cells to colonize lymph nodes.

1996 • 240 citations

The Sequential Role of Lymphotoxin and B Cells in the Development of Splenic Follicles

1998 • 232 citations

Essential role of IL-7 receptor alpha in the formation of Peyer's patch anlage

1998 • 161 citations

Lymphotoxin‐α‐deficient and TNF receptor‐I‐deficient mice define developmental and functional characteristics of germinal centers

1997 • 149 citations

Distinct Roles of Lymphotoxin α and the Type I Tumor Necrosis Factor (TNF) Receptor in the Establishment of Follicular Dendritic Cells from Non–Bone Marrow–derived Cells

1997 • 131 citations

Mouse lymphotoxin-beta receptor. Molecular genetics, ligand binding, and expression.

1995 • 118 citations

To ‘B’ or not to ‘B’ a germinal center?

1997 • 114 citations

The splenic marginal zone is absent in alymphoplastic aly mutant mice

1996 • 94 citations

A Role for Tumor Necrosis Factor Receptor Type 1 in Gut-associated Lymphoid Tissue Development: Genetic Evidence of Synergism with Lymphotoxin β

1998 • 74 citations

Crucial Role of Tumor Necrosis Factor Receptor 1 Expression on Nonhematopoietic Cells for B Cell Localization within the Splenic White Pulp

1998 • 65 citations

Defects of somatic hypermutation and class switching in alymphoplasia (aly) mutant mice

1996 • 63 citations

Complementation of Lymphotoxin α Knockout Mice with Tumor Necrosis Factor–expressing Transgenes Rectifies Defective Splenic Structure and Function

1998 • 61 citations

Absence of lymph nodes in lymphotoxin-alpha(LT alpha)-deficient mice is due to abnormal organ development, not defective lymphocyte migration.

1995 • 53 citations

The postnatal development of high‐endothelial venules in lymph nodes of mice

1975 • 43 citations

Transgenic expression of lymphotoxin restores lymph nodes to lymphotoxin-alpha-deficient mice.

1997 • 33 citations

Lymphotoxins: From cytotoxicity to lymphoid organogenesis

1997 • 23 citations

The alymphoplasia (aly) mutation co-segregates with the intercellular adhesion molecule-2 (lcam-2) on mouse chromosome 11

1994 • 22 citations

Pluripotency of Homozygous‐Diploid Mouse Embryos in Chimeras

1987 • 18 citations