T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART)

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

Changes in thymic function with age and during the treatment of HIV infection

1998 • 1,887 citations

Positive Effects of Combined Antiretroviral Therapy on CD4 ⁺ T Cell Homeostasis and Function in Advanced HIV Disease

1997 • 1,812 citations

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

1998 • 1,426 citations

Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

1997 • 1,391 citations

Programmed Death of T Cells in HIV-1 Infection

1992 • 932 citations

Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67.

1991 • 891 citations

Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation

1998 • 722 citations

Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

1999 • 598 citations

CD8 naive T cell counts decrease progressively in HIV-infected adults.

1995 • 495 citations

Rapid Turnover of T Lymphocytes in SIV-Infected Rhesus Macaques

1998 • 375 citations

Cell cycle dependent expression and stability of the nuclear protein detected by Ki‐67 antibody in HL‐60 cells

1992 • 368 citations

Initial increase in blood CD4+ lymphocytes after HIV antiretroviral therapy reflects redistribution from lymphoid tissues

1999 • 339 citations

Alterations in the Immune Response of Human Immunodeficiency Virus (HIV)-Infected Subjects Treated with an HIV-Specific Protease Inhibitor, Ritonavir

1996 • 338 citations

Turnover of CD4+ and CD8+ T Lymphocytes in HIV-1 Infection as Measured by Ki-67 Antigen

1998 • 337 citations

T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4 ⁺ T Cell Turnover

1996 • 288 citations

Failure of T-cell homeostasis preceding AIDS in HIV-1 infection

1995 • 235 citations

Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection

1998 • 224 citations

Limited CD4+ T-cell renewal in early HIV-1 infection: Effect of highly active antiretroviral therapy

1998 • 153 citations

Programmed death of T cells in human immunodeficiency virus infection. No correlation with progression to disease.

1994 • 152 citations

Determination of the growth fraction in cell suspensions by flow cytometry using the monoclonal antibody Ki-67

1986 • 150 citations

Heterogeneity of the circulating human CD4+ T cell population. Further evidence that the CD4+CD45RA-CD27- T cell subset contains specialized primed T cells.

1995 • 117 citations

Increased rates of CD4⁺and CD8⁺T lymphocyte turnover in simian immunodeficiency virus-infected macaques

1998 • 104 citations

A Novel Mechanism of CD4 Lymphocyte Depletion Involves Effects of HIV on Resting Lymphocytes: Induction of Lymph Node Homing and Apoptosis Upon Secondary Signaling Through Homing Receptors

1999 • 79 citations

T Cell Dynamics in HIV-1 Infection

1999 • 72 citations

Rapid CD4+ T-cell turnover in HIV-1 infection: A paradigm revisited

1998 • 71 citations

Randomized trial comparing saquinavir soft gelatin capsules versus indinavir as part of triple therapy (CHEESE study)

1999 • 58 citations

HIV infection: where have all the T cells gone?

1999 • 55 citations

T Cell Turnover in SIV Infection

1999 • 46 citations

Cryopreservation of cells for immunological typing of non-Hodgkin's lymphomas.

1980 • 39 citations

Normal Telomere Lengths in Naive and Memory CD4+ T Cells in HIV Type 1 Infection: A Mathematical Interpretation

1999 • 33 citations

Lymphocyte Kinetics and Precursor Frequency-Dependent Recovery of CD4+CD45RA+CD62L+ Naive T Cells Following Triple-Drug Therapy for HIV Type 1 Infection

1999 • 31 citations

Normal T-Cell Telomerase Activity and Upregulation in Human Immunodeficiency Virus-1 Infection

1999 • 23 citations